CAS: 118276-06-5; 3,5-Difluoro-4-Hydroxybenzaldehyde

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参考文献:1,3-Diphenylprop-2-En-1-One Derivative Compounds,Preparation Method Thereof And Uses Of Same
标题:1,3-Diphenylprop-2-En-1-One Derivative Compounds,Preparation Method Thereof And Uses Of Same
摘要:该发明涉及替代的1,3-二苯基丙烯酮衍生物化合物,含有该化合物的药用和/或化妆品组合物,以及在治疗学和化妆品学中的应用.该发明还涉及一种制备上述衍生物的方法.

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.