CAS: 10034-96-5; Manganese(Ii) Sulfate Hydrate

相似化合物

19513-05-4 15244-38-9 95838-16-7

专利信息

专利号:US-2009197311-A1
优先权日:2006-06-20
标题:Method for the production of simvastatin
发明人：BERG MARCO ALEXANDER VAN DEN; HANS MARCUS; STREEKSTRA HUGO
权利人:BERG MARCO ALEXANDER VAN DEN; HANS MARCUS; STREEKSTRA HUGO
摘要:The present invention provides a fermentative process for the synthesis of simvastatin by providing a host capable of incorporating the 2,2-dimethylbutyrate side chain into simvastatin, i.e. by customizing a polyketide synthase gene optimized for synthesis and/or incorporation of 2,2-dimethylbutyrate; optionally feeding said host with the appropriate substrate for 2,2-dimethylbutyrate synthesis; fermenting said host to obtain simvastatin or analogues or derivatives thereof, i.e. by producing simvastatin on an industrial scale by a fed-batch process.

专利号:US-12049655-B2
优先权日:2021-08-06
标 题 :Construction method and application of microorganism capable of realizing high production of lacto-N-tetrose
发明人：MU WANMENG; ZHU YINGYING; LI ZEYU; ZHANG WENLI
权利人:UNIV JIANGNAN
摘要:Disclosed are a construction method and application of a microorganism capable of realizing high production of lacto-N-tetrose, belonging to the field of microbial genetic engineering. The present disclosure employs a strain which has been constructed in the early stage for efficiently producing a precursor lacto-N-triose II as an original strain to synthesize a key gene of the lacto-N-tetrose via over-expression, thus enabling the strain to have a synthesis capability of producing the lacto-N-tetrose. The present disclosure improves the synthesis of the lacto-N-tetrose by screening a high-efficiency β-1,3-galactosyl transferase gene, and reasonably designing the co-expression of the β-1,3-galactosyl transferase gene and a key UDP-glucose 4 epimerase gene (galE) for strengthening a UDP-galactose pathway on a vector pCDFDuet-1. In a shake flask experiment, the lacto-N-tetrose production capacity of Escherichia coli is 3.04 g/L. The lacto-N-tetrose yield in a 3 L fermentation tank reaches 25.49 g/L. Therefore, the microorganism has an industrial application prospect.

专利号:US-11390890-B2
优先权日:2015-02-15
标 题:Dibasic organic acid producing strain and preparation and application of same
发明人：TIAN CHAOGUANG; LI JINGEN; LONG CHUANNAN; SUN TAO; LIN LIANGCAI; XU JING; LIU QIAN; JI JINGXIAO; SUN WENLIANG; MA YANHE
权利人:TIANJIN INST IND BIOTECHNOLOGY CAS
摘要:Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or up-regulates expression of a positive regulator gene for synthesis of a dibasic organic acid, and/or down-regulates expression of a negative regulator gene for synthesis of a dibasic organic acid, as compared with the origin strain of the engineered strain, the producing capability for producing the dibasic organic acid is improved. The dibasic organic acid comprises malic acid, succinic acid, fumaric acid, oxaloacetic acid, glutaric acid, and adipic acid; the expression product of the positive regulator gene comprises aspartate aminotransferase, glutamic acid-aspartate transporter, C4-dicarboxylic acid transporter, pyruvate carboxylase and malate dehydrogenase, glucose transporter; the expression product of the negative regulatory gene comprises succinyl-CoA synthase, and malic acid-alpha ketoglutarate transporter, and the original strain comprises Myceliophthora thermophila, Thielavia terrestris, Aspergillus , and Rhizopus.

专利号:US-2004128713-A1
优先权日:1997-04-08
标题 :Soybean plant producing seeds with reduced levels of raffinose saccharides and phytic acid
发明人：HITZ WILLIAM D; SEBASTIAN SCOTT ANTHONY; GRACE DORMAN JOHN; STREIT LEON GEORGE
摘要:A soybean enzyme, myo-inositol 1-phosphate synthase, whose manipulation results in the alteration of raffinose saccharide, sucrose, phytic acid and inorganic phosphate content of soybean seeds, thus leading to valuable and useful soybean products, has been identifed. Soybean lines with decreased capacity for the synthesis of myo-inositol 1-phosphate in the tissue of developing seeds in comparison to seeds of other soybean lines, have been developed. As taught herein, reduction of myo-inositol 1-phosphate synthase enzymatic activity by any of several means will result in soybean seeds displaying this desirable phenotype.

专利号:US-2017204442-A1
优先权日:2014-05-29
标题 :Enzymatic synthesis of soluble glucan fiber
发明人：DICOSIMO ROBERT; CHENG QIONG; ELIOT ANDREW C; OUWEHAND ARTHUR; PAYNE MARK S; YOU ZHENG
权利人:DU PONT
摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.

专利号:US-2025034607-A1
优先权日:2021-12-03
标题 :Process of Synthesizing (R)-3-aminobutan-1-ol
发明人：BOBKO MARK; FUERST DOUGLAS; MORGAN CHRISTOPHER
权利人:VIIV HEALTHCARE CO
摘要:The present invention relates to an aminotransaminase useful in the synthesis of (R)-3-aminobutan-1-ol (RABO). The present invention also provides a process of preparing (R)-3-aminobutan-1-ol (RABO) with the disclosed aminotransaminase.