CAS: 67306-00-7; 1-[3-(4-Tert-Butylphenyl)-2-Methylpropyl]Piperidine

该化合物是一种属于管虫类的系统性杀真菌剂,主要用于控制微量粉和其他谷类和园艺作物中的真菌病原体,其作用方式包括抑制乙醇生物合成物,特别是C14-demothase酶酶(CYP51),该酶会破坏真菌细胞膜的完整性;芬丙丁表现出强烈的跨月和植物类运动,确保有效保护新生长;主要优势包括长效残留活动,耐雨性以及符合综合虫害管理方案;特别重视其低应用率的功效和在用作指导时对非目标生物的影响最小;由于其独特的生物化学目标,适合抗药管理战略.

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欧盟法规

[ECHA物质ECHA物质C&L通报REACH预注册

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CAS号67306-24-5 1-[3-(p-tert.bu... | CAS号74879-98-4 1-(2-methyl-3-p... | CAS号115-11-7 2-甲基丙烯 | CAS号75-65-0 叔丁醇

合成工艺路线路线简述

    📜1-<3-(P-Tert.Butylphenyl)-2-Methyl-2-Propenyl>-Piperidin置于palladium-Carbon 盐酸,Sodium Hydroxide体系中,化学反应生成 苯锈啶
    参考文献:Heterocyclics Useful As Fungicides And Fungicidal Compositions Thereof
    标题:Heterocyclics Useful As Fungicides And Fungicidal Compositions Thereof
    摘要:以公式##str1##为特征的杂环化合物,其中r1,R3,R4,R5,R6,X和z如后文所述,通过至少与一种公比为##str2##的化合物与一种公比为##str3##的胺反应而制备,其中r1,R3,R4,R5,R6,X和y如后文所述.所述最终产品可用作杀真菌剂.

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-2016073631-A1
    优先权日:2013-03-04
    标 题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-9233920-B2
    优先权日:2010-06-11
    标题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-5733755-A
    优先权日:1995-11-24
    标题 :Method for the enantioselective synthesis of chiral derivatives of S-3-(4'-t
    发明人:SUNJIC VITOMIR; MAJERIC MAJA; HAMERSAK ZDENKO; AVDAGIC AMIR
    权利人:CAFFARO SPA IND CHIM
    摘要:A method for manufacturing S-3-(4'-tert-butyl)-phenyl-2-methyl propylamines having the structure I ##STR1## where NR 1 R 2 is a dialkylamine group, pyrrolidine, piperidine, or cis-3,5-dimethyl morpholine, comprising a reduction of the compound having the structure II ##STR2##

    专利号:US-10906880-B2
    优先权日:2016-01-26
    标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
    发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
    权利人:UNIV NANKAI
    摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

    专利号:US-9968097-B2
    优先权日:2012-05-30
    标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
    发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
    权利人:BAYER CROPSCIENCE AG
    摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Zhao H, Xue J, Jiang N, Peng W, Liu F. Dissipation and residue of fenpropidin in wheat and soil under field conditions. Ecotoxicol Environ Saf. 2012 Mar;77:52-6. doi: 10.1016/j.ecoenv.2011.10.017. Epub 2011 Nov 9. doi: 10.1021/acs.jafc.6b00919. Epub 2016 Jun 24. Epub 2005 Oct 26. doi: 10.1021/acsmedchemlett.5b00245. eCollection 2015 Nov 12.
    5: Bro E, Devillers J, Millot F, Decors A. Residues of plant protection products in grey partridge eggs in French cereal ecosystems. Environ Sci Pollut Res Int. 2016 May;23(10):9559-73. doi: 10.1007/s11356-016-6093-7. Epub 2016 Feb 3.
    6: Bedos C, Rousseau-Djabri MF, Loubet B, Durand B, Flura D, Briand O, Barriuso E. Fungicide volatilization measurements: inverse modeling, role of vapor pressure, and state of foliar residue. Environ Sci Technol. 2010 Apr 1;44(7):2522-8. doi: 10.1021/es9030547. doi: 10.1007/s11356-009-0284-4. Epub 2010 Jan 15. doi: 10.1099/mic.0.045690-0. Epub 2011 Mar 24. doi: 10.1080/19440049.2016.1209575. Epub 2016 Jul 25. doi: 10.1016/j.scitotenv.2016.01.058. Epub 2016 Feb 6. Epub 2007 Nov 7.

    合成参考文献


    摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
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