📜对乙酰胺基苯磺酰氯置于sodium Hydroxide体系中,化学反应生成 磺胺培林 参考文献:Sulfonamido Derivatives Of Pyrimidines 标题:Sulfonamido Derivatives Of Pyrimidines 摘要: DOI:10.1021/ja01856A046
专利信息
专利号:WO-0146695-A1 优先权日:1999-12-08 标 题:Novel supports for solid phase synthesis 发明人:ANTONENKO VALERY V; THIELE JOCHEN; ATUEGBU ANDY E 权利人:GLAXO GROUP LTD; ANTONENKO VALERY V; THIELE JOCHEN; ATUEGBU ANDY E 摘要:Novel solid supports and methods for their use in the synthesis of chemical compounds by the sequential addition of chemical building blocks are provided. The solid support comprises a polymer having reactive groups (for example, poly(styrene-co-vinylbenzyl chloride)) grafted to a chemically inert bulk material (such as a Teflon® membrane).
专利号:US-2007021349-A1 优先权日:2005-04-28 标题:Orthogonally protected bifunctional amino acid 发明人:SRINIVASAN ANANTH; LUYT LEONARD G 权利人:SRINIVASAN ANANTH; LUYT LEONARD G 摘要:The present invention concerns novel orthogonally protected amino acids, there production and use for the synthesis of binding compounds usable in the diagnosis and treatment of proliferative diseases, in particular tumor diseases.
专利号:US-9295731-B2 优先权日:2013-04-01 标题 :Cleavable drug conjugates, compositions thereof and methods of use 发明人:NGUYEN MARK QUANG 权利人:NGUYEN MARK QUANG 摘要:Base-labile crosslinkers, base-labile conjugates comprising such crosslinkers, methods of their synthesis and use are disclosed.
专利号:WO-2006114323-A3 优先权日:2005-04-28 标题 :Orthogonally protected bifunctional amino acid 发明人:SRINIVASAN ANANTH; LUYT LEONARD G 权利人:SCHERING AG; SRINIVASAN ANANTH; LUYT LEONARD G 摘要:The present invention concerns novel orthogonally protected amino acids, there production and use for the synthesis of binding Compounds usable in the diagnosis and treatment of proliferative diseases, in particular tumor diseases.
专利号:CN-1478772-A 优先权日:2002-08-28 标 题:Synthesis method of -N-phenyl-N'-pyridyl substituted carbamide derivative
专利号:CN-1169796-C 优先权日:2002-10-21 标题:Catalytic synthesis process of methyl substituted pyrimidyl urea derivative
1: Losch K. [Pharmacokinetic studies of sulfamerazine-Na, sulfaperine-Na and sulfadimidine-Na in the hen]. Arch Exp Veterinarmed. 1980;34(4):587-94. German. Danish.
合成参考文献
摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664 参考文献:10.1002/cptx.16 摘要:Wages PA. Detecting Protein Sulfenylation in Cells Exposed to a Toxicant. Curr Protoc Toxicol. 2017 Feb 01;71():17.18.1–17.18.12. 参考文献:10.1002/bies.10114 摘要:Bermingham A, Derrick JP. The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery. Bioessays. 2002 Jul;24(7):637–48. doi: 10.1002/bies.10114.