CAS: 4779-94-6; Norphenylephrine Hydrochloride
该化合物是一种化学化合物,其结构特征包括苯环,羟基甲基组和氨基组,其特性一般是白色的脱白晶状固体,由于盐酸碱存在,可溶于水中.氨基组有助于其基本性,而氢氧组可以参与氢的结合,影响其再活动及与其他物质的相互作用.该化合物经常因其在制药和生物化学领域的潜在应用,特别是在药物研制和合成方面的潜在应用而加以研究,其特性,如熔点和稳定性,可因环境条件和其他化学实体的存在而不同.与许多有机化合物一样,在处理该物质时,应注意安全防范措施,因为如果采用或不适当地管理,可能会对健康造成危害.
- 英文名称Norphenylephrine Hydrochloride
- 中文名称盐酸去甲苯福林
- IUPAC名称Benzenemethanol, alpha-(aminomethyl)-3-hydroxy-, hydrochloride (9CI)
- 其它别名Benzenemethanol,a-(aminomethyl)-3-hydroxy-,hydr°Chloride (9CI); Benzyl alcohol, a-(aminomethyl)-m-hydroxy-, hydr°Chloride (6CI,8CI); (?à)-Norphenylephrine hydr°Chloride; (?à)-m-°Ctopamine hydr°Chloride; 1-(m-Hydroxyphenyl)-2-aminoethanol hydr°Chloride; 2-Amino-1-(3-hydroxyphenyl)ethanol hydr°Chloride; Coritat; DL-m-°Ctopaminehydr°Chloride; Depot-Novadral; Energona; Esbuphon; Molycor R; Norfenefrin; Norfenefrine hydr°Chloride; Norphenephrine hydr°Chloride; Norphenylephrine hydr°Chloride; Novadral; Stagural; Tonolift; Vingsal; Zondel; dl-Norfenefrine hydr°Chloride; m-°Ctopamine hydr°Chloride; a-(Aminomethyl)-m-hydroxybenzylalcohol hydr°Chloride
- CAS编号4779-94-6
- MFCD编号:MFCD00012879
- EINECS号:225-323-6
- FDA UNII编号:1FCN9TAU6R
- 分子式:C8H11NO2.ClH分子量:189.64
- 产品CID: 1472498
- 同类组份化合物CAS536-21-0 (free base)4779-94-6 (HCl)1420-80-0 (S-isomer)5596-07-6 (R-isomer)
- 产品分类原料药 → 循环系统用药 → 抗休克血管活性药
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号79680-88-9 1-(3-hydroxyphe... | CAS号23824-30-8 1,2,3,4-Tetrahy...合成工艺路线路线简述
📜1-(3-羟基苯基)-2-(苄基氨基)乙醇置于钯 盐酸,氢气体系中,用 乙醇 作为反应溶剂,以98.3%的收率获得产物盐酸去甲苯福林
参考文献:Synthesis And Radioprotectant Properties Of Some 6-Hydroxy-L,2,3,4-Tetrahydroisoquinolines
标题:Synthesis And Radioprotectant Properties Of Some 6-Hydroxy-L,2,3,4-Tetrahydroisoquinolines
摘要:
DOI:10.1007/bf00760706
海关参考信息
- 2902600000-乙苯
2906210000-苄醇
2922110001-单乙醇胺
2908199090-其他酚的卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5405872-A
优先权日:1990-09-22
标 题 :Anti-hypertensive tetralins
发明人：MCDERMED JOHN D; HURLEY KEVIN P; CHANG VINCENT H; TADEPALLI ANJANEYULU S
权利人:BURROUGHS WELLCOME CO
摘要:PCT No. PCT/GB91/01602 Sec. 371 Date Mar. 22, 1993 Sec. 102(e) Date Mar. 22, 1993 PCT Filed Sep. 19, 1991 PCT Pub. No. WO92/05143 PCT Pub. Date Apr. 2, 1992.This invention relates to tetralin derivatives useful in medicine for the treatment of hypertension, to the synthesis of the compounds, to the pharmaceutical formulations containing the compounds and the use of the compounds in medical practice.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Magometschnigg D, Stengele E. Norfenefrine: haemodynamic effects in healthy volunteers at rest and during orthostasis. Eur J Clin Pharmacol. 1983;25(2):167-71. German. German. German. German. German. German. German. Epub 2004 Feb 24.
合成参考文献
摘要:Drugs in Japan, 6(569), 1982
摘要:Gekkan Yakuji. Pharmaceuticals Monthly., 23(1587), 1981
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