CAS: 402-50-6; 1-(Trifluoromethyl)-4-Vinylbenzene

该化合物是一种有机化合物,其特征是存在一个带有三氟甲基组(-CF3)且附在苯环的副位置上的苯基柱质(-CF3),该化合物在室内温度下无色可粉黄,以其独特的芳香味闻名;由于存在三氟甲基组,该化合物相对非极性,因为它会增加其脂度,并可能影响其在有机溶剂中的再活性和溶解性;该三氟甲基组还具有独特的电子特性,使4-(三氟甲基)苯成为有机合成和材料科学中有价值的建筑块;该化合物可经受各种化学反应,包括聚合,在那里可以用来制造具有理想热和化学抗力的氟聚合物;在处理该化合物时,应采取安全防范措施,因为如果吸入或浸入,可能会对健康造成危害.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

2-(p-Trifluoromethylphenyl)-aethyltrimethylammoniumbromid 1-(4-trifluorophenyl)ethanol 1-(4-trifluoromethylphenyl)-2-trimethylsilylethanol ethyl>trimethylammonium iodide2-ethyltrimethylammonium iodide 2-Methyl-4-(p-trifluormethyl)-1-penten 2-Methyl-5-(p-trifluormethylphenyl)-1-penten 1-(1,2-dibromoethyl)-4-(trifluoromethyl)benzene 1-(2-bromovinyl)-4-(trifluoromethyl)benzene

合成工艺路线路线简述

    📜4-三氟甲基苯基溴化镁置于potassium Hydrogensulfate体系中,化学反应生成 对三氟甲基苯乙烯
    参考文献:A New Method Of Evaluating Ortho σ-Constants
    标题:A New Method Of Evaluating Ortho σ-Constants
    摘要:
    DOI:10.1021/ja00904A042

    海关参考信息

    专利信息


    专利号:US-6710208-B2
    优先权日:1996-12-19
    标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARMA INC
    摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-9243008-B1
    优先权日:2015-02-11
    标 题 :Functionalized unsaturated derivatives of (dimethylvinylgermoxy)heptasubstituted silsesquioxanes and the method of their synthesis
    发明人:FRÄ„CKOWIAK DAWID; Å»AK PATRYCJA; MARCINIEC BOGDAN
    权利人:UNIV ADAM MICKIEWICZ
    摘要:The invention relates to new functionalized unsaturated derivatives of (dimethylvinylgermoxy)heptasubstituted silsesquioxanes of the general formula 1, n nand the method in which:n R are the same and represent linear and branched C 2 to C 8 alkyl groups, or cyclopentyl and cyclohexyl groups, or phenyl groups R′ represents an unsubstituted aryl group containing between 1 and 2 rings or an aryl group substituted in any position in the ring. nn The invention also relates to the method of synthesis of functionalized unsaturated derivatives of (dimethylvinylgermoxy)heptasubstituted silsesquioxanes.

    专利号:US-8541524-B2
    优先权日:2006-07-04
    标 题 :Free-radical polymerization process in aqueous dispersion for the preparation of a block copolymer at least one block of which is a block of a halogenated polymer
    发明人:FRINGANT CHRISTOPHE; VANDERVEKEN YVES; LACROIX-DESMAZES PATRICK; TONNAR JEFF
    权利人:FRINGANT CHRISTOPHE; VANDERVEKEN YVES; LACROIX-DESMAZES PATRICK; TONNAR JEFF; SOLVAY
    摘要:Process of controlled free-radical polymerization in aqueous dispersion for the preparation of a block copolymer at least one block of which is a block of a halogenated polymer using molecular iodine and at least one oxidant whose solubility in water is at least 10 g/l for the synthesis of the first block of the block copolymer.

    专利号:EP-2647639-A1
    优先权日:2012-04-06
    标题:ß-boration of alkene and alkyne intermediates
    权利人:LEK PHARMACEUTICALS
    摘要:The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.

    专利号:EP-2647640-A1
    优先权日:2012-04-06
    标 题:ß-boration of alkene and alkyne intermediates
    权利人:LEK PHARMACEUTICALS
    摘要:The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-boated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.

    专利号:UA-71917-C2
    优先权日:1998-06-24
    标题:A PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDE OF a, b- UNSATURATED ALKENOATE RESIN

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Black, D. A.; Fagnou, K., Science of Synthesis, (2010) 45, 629.
    摘要:Amatore, M.; Aubert, C.; Malacria, M.; Petit, M., Science of Synthesis Knowledge Updates, (2012) 3, 88.
    摘要:Li, Y.; Xie, W.; Jiang, X., Science of Synthesis Knowledge Updates, (2016) 2, 16.
    摘要:Hannedouche, J., Science of Synthesis Knowledge Updates, (2013) 4, 31.
    摘要:de Haro, T.; Garayalde, D.; Nevado, C., Science of Synthesis Knowledge Updates, (2012) 2, 202.
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