CAS: 352-91-0; 1-Bromo-3-Fluoropropane

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462-72-6 407-97-6

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CAS号109-64-8 1,3-二溴丙烷 | CAS号462-43-1 3-氟丙醇 | CAS号2623-87-2 4-溴丁酸 | CAS号109-70-6 1-溴-3-氯丙烷 | CAS号103935-48-4 3-bromopropyl-1... | CAS号107-21-1 乙二醇 | CAS号462-39-5 1,3-二氟丙烷 | CAS号462-40-8 3-氟-1-碘代丙烷 | CAS号63636-89-5 吡啶-2-磺酰胺 | CAS号133120-18-0 3-(3-fluoroprop... | CAS号155797-99-2 8-AZABICYCLO[3.... | CAS号648956-81-4 2-(3-fluoroprop... | CAS号462-74-8 4-Fluorobutyral... | CAS号407-83-0 4-fluorobutanen... | CAS号408-00-4 Thi°Cyanic acid...

3-溴丙基三氟甲烷磺酸酯置于四丁基氟化铵体系中,用 邻二氯苯 用作溶剂,化学反应 0.05H,反应生成1-溴-3-氟丙烷
参考文献:A Rapid And Efficient Method For The Fluoroalkylation Of Amines And Amides. Development Of A Method Suitable For Incorporation Of The Short-Lived Positron Emitting Radionuclide Fluorine-18
标题:A Rapid And Efficient Method For The Fluoroalkylation Of Amines And Amides. Development Of A Method Suitable For Incorporation Of The Short-Lived Positron Emitting Radionuclide Fluorine-18
摘要:
Doi:10.1021/jo00380A030

专利信息

专利号:US-8975427-B2
优先权日:2010-04-28
标题 :Synthesis of alkyl cyclopentadiene compounds
发明人：HARLAN C JEFF; CAO XIANYI; RIX FRANCIS C
权利人:HARLAN C JEFF; CAO XIANYI; RIX FRANCIS C; UNIVATION TECH LLC
摘要:A method of synthesizing an alkyl cyclopentadiene compound is disclosed. The method includes contacting at least one cyclopentadienyl anion source and at least one alkyl group source to form at least one alkyl cyclopentadiene compound. The method further includes extracting the alkyl cyclopentadiene compound with a hydrocarbon solvent. The alkyl cyclopentadiene compound may be converted to a metallocene catalyst compound.

专利号:US-9371334-B2
优先权日:2010-09-22
标题:Synthesis of substituted salicylaldehyde derivatives
发明人：FARMER JAY J; JOB GABRIEL E
权利人:NOVOMER INC
摘要:Among other things, the present invention encompasses methods of synthesizing salicylaldehyde derivatives comprising the steps of: a) providing salicylaldehyde or a derivative thereof, b) forming an anhydro dimer of the provided salicylaldehyde compound, c) performing one or more chemical transformations on the anhydro dimer and d) hydrolyzing the anhydro dimer to provide a salicylaldehyde derivative different from that provided in step (a).

专利号:US-2022009919-A1
优先权日:2009-12-17
标题:Preparation of n-monofluoroalkyl compounds
发明人：WILLIAMS LORENZO; KEILEN GUNNAR; HAUGAN JARLE ANDRE
权利人:GE HEALTHCARE LTD
摘要:The present invention relates to an improved synthesis of N-monofluoroalkyl tropanes using fluoroalkyl iodide. The invention also provides the use of such method to prepare the non-radioactive tropane intermediate FP-CIT, and its subsequent conversion to the 123 I-labelled radiopharmaceutical DaTSCANâ„¢ ( 123 I-ioflupane). Also provided is the use of fluoroalkyl iodide in the alkylation method of the invention.

专利号:US-8895741-B2
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidinones
发明人：WU YUSHENG; CHEN SHILI; CHEN YI; HANSELMANN ROGER; LOU RONGLIANG; ZHOU JIACHENG
权利人:WU YUSHENG; CHEN SHILI; CHEN YI; HANSELMANN ROGER; LOU RONGLIANG; ZHOU JIACHENG; MELINTA THERAPEUTICS INC
摘要:The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

专利号:US-5985844-A
优先权日:1992-03-26
标题:Homoerythromycin A derivatives modified at the 4'-and 8A-positions
发明人：HECK JAMES V; LEANZA WILLIAM J; RATCLIFFE RONALD W; SALZMANN THOMAS N; SHANKARAN KOTHANDARAMAN; SZYMONIFKA MICHAEL J; WILKENING ROBERT R
权利人:MERCK & CO INC
摘要:Compounds of the formula: where R is hydrogen, hydroxyl, alkyl or acyl, R' and R'' together are oxo, hydroxyimino or alkoxyimino, and R' and R'' independently are hydrogen, hydroxyl, acyloxy, or amino substituted by any of hydrogen, alkylcarbonyl, arylcarbonyl, aralkylcarbonyl, alkoxycarbonyl, aralkoxycarbonyl, alkylsulfonyl or arylsulfonyl, and n is 0 or 1, and the pharmaceutically acceptable salts thereof. The compounds are macrolide antibiotics and are also useful as intermediates to the synthesis of other macrolide antibiotics. Pharmaceutical compositions and methods of their use are also provided for.

专利号:US-2010022772-A1
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidnones