N-{(1S,2R,3S,4R)-4-((2R,3R,4R,5R)-3,5-Dihydroxy-5-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-3-hydroxy-2-[(2R,3R,6S)-6-(1-methylamino-ethyl)-3-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-2-yloxy]-5-oxo-cyclohexyl}-2,2,2-trifluoro-acetamide; compound with sulfuric acid
合成工艺路线路线简述
📜(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[(2R,3R,6S)-3-Amino-6-(1-Aminoethyl)Oxan-2-Yl]Oxy-2-Hydroxycyclohexyl]Oxy-5-Methyl-4-(Methylamino)Oxane-3,5-Diol;(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[(2R,3R,6S)-3-Amino-6-(Aminomethyl)Oxan-2-Yl]Oxy-2-Hydroxycyclohexyl]Oxy-5-Methyl-4-(Methylamino)Oxane-3,5-Diol;(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[(2R,3R,6S)-3-Amino-6-[1-(Methylamino)Ethyl]Oxan-2-Yl]Oxy-2-Hydroxycyclohexyl]Oxy-5-Methyl-4-(Methylamino)Oxane-3,5-Diol;Sulfuric Acid 以 水 用作溶剂,化学反应 228.0H,反应生成庆大霉素c1五乙酸酯盐 参考文献:Method For Making Solvent Dilution Microcarriers 标题:Method For Making Solvent Dilution Microcarriers 摘要:本申请公开了一种制备被命名用作溶剂稀释微载体(sdmcs)的包封乘客分子的车辆的方法及其产品,该方法允许在通过溶解两性亲和性双层形成材料,适当的溶剂和乘客分子,加入水溶液和进一步加入溶剂形成的货架稳定的成型溶液后,立即或延迟形成包封车辆.通过将成型溶液稀释成水系,气溶胶化或在原位重水化,可以从成型溶液中组织sdmcs.
专利号:US-2024287564-A1 优先权日:2021-06-07 标题 :Acholetin biopolymers and methods for enzymatic synthesis 发明人:WITHERS STEPHEN G; MACDONALD SPENCER S S 权利人:UNIV BRITISH COLUMBIA 摘要:Provided herein are β-1,3-linked biopolymers (acholetin polysaccharides). Furthermore, provided herein are enzymatic methods and systems for producing β-1,3-linked oligosaccharides and polysaccharides using β-1,3-N-acetylglucosaminide phosphorylase (Acholetin phosphorylase (AchP)). The AchP was sourced from the genome of the cell wall-less Mollicute bacterium, Acholeplasma laidlawii and was found to synthesize β-1,3-linked N-acetylglucosamine (GlcNAc) or N-acetylgalactosamine (GalNAc) oligomers using the donor. α-N-acetylglucosamine 1-phosphate (GlcNAc1-P) or N-acetylgalactosamine 1-phosphate (GalNAc1-P).
专利号:CN-118638197-A 优先权日:2024-04-30 标题:DkBBX3 transcription factor for regulating and controlling synthesis of plant procyanidine, nucleic acid molecule and application
专利号:US-7179794-B2 优先权日:1998-06-08 标题 :Multivalent macrolide antibiotics 发明人:GRIFFIN JOHN H; PACE JOHN L 权利人:THERAVANCE INC 摘要:Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial ribosomal RNA and/or to one or more proteins involved in ribosomal protein synthesis in the bacterium, which are useful in treating bacterial infections. The compounds adversely affect protein expression and have an antibacterial effect. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is macrolide antibiotic, aminoglycoside, lincosamide, oxazolidinone, streptogramin, tetracycline or other compound which binds to bacterial ribosomal RNA and/or one or more proteins involved in ribosomal protein synthesis in the bacterium.
专利号:WO-2024205297-A1 优先权日:2023-03-29 标题:Novel bifidobacterium and/or lactobacillus strain or combination thereof and uses thereof 发明人:PARK DOO-SANG; LEE KWANG-PYO; YANG YONG RYOUL; KIM MINJU; KIM SEUNG HYUN; YANG JAEWON 权利人:KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY 摘要:The present invention relates to two types of novel Bifidobacterium animalis subspecies lactis strains, a Lactobacillus paracasei strain, a Lactobacillus gasseri strain, or a combination thereof and uses thereof. The strains increase mitochondrial synthesis by increasing the activity of AMP-activated protein kinase (AMPK) protein present in muscle cells, thereby improving the ability of muscles to perform exercise, and thus can be used for the improvement of muscle function or can be effectively used as a medicine, a health functional food, or a food, for the prevention, amelioration or treatment of muscle diseases.
专利号:CN-112626075-B 优先权日:2019-10-08 标题 :Cloning primer, function and application of a SmAP2/ERF152 gene regulating tanshinone synthesis
专利号:CN-119410676-A 优先权日:2025-01-07 标题:Hopane synthesis gene combination and application thereof in enhancing environmental stress tolerance of rhizobia in wide hosts
参考文献:10.1007/s00253-010-2464-z 摘要:Zhou Q, Su J, Jiang H, Huang X, Xu Y. Optimization of phenazine-1-carboxylic acid production by a gacA/qscR-inactivated Pseudomonas sp. M18GQ harboring pME6032Phz using response surface methodology. Applied Microbiology and Biotechnology. 2010 Feb 13;86(6):1761–73. doi: 10.1007/s00253-010-2464-z. 参考文献:10.1007/s00417-009-1282-4 摘要:Hata Y, Miura M, Asato R, Kita T, Oba K, Kawahara S, Arita R, Kohno R, Nakao S, Ishibashi T. Antiangiogenic mechanisms of simvastatin in retinal endothelial cells. Graefe's Archive for Clinical and Experimental Ophthalmology. 2010 Feb 13;248(5):667–73. doi: 10.1007/s00417-009-1282-4. 参考文献:10.1007/s00423-010-0601-x 摘要:Binnebösel M, Ricken C, Klink CD, Junge K, Jansen M, Schumpelick V, Lynen Jansen P. Impact of gentamicin-supplemented polyvinylidenfluoride mesh materials on MMP-2 expression and tissue integration in a transgenic mice model. Langenbecks Arch Surg. 2010 Apr;395(4):413–20. doi: 10.1007/s00423-010-0601-x. 参考文献:10.1007/s11095-009-0042-9 摘要:Eljarrat-Binstock E, Pe’er J, Domb AJ. New Techniques for Drug Delivery to the Posterior Eye Segment. Pharmaceutical Research. 2010 Feb 13;27(4):530–43. doi: 10.1007/s11095-009-0042-9. 参考文献:10.1007/s00792-010-0303-x 摘要:Romano I, Dipasquale L, Orlando P, Lama L, d'Ippolito G, Pascual J, Gambacorta A. Thermoanaerobacterium thermostercus sp. nov., a new anaerobic thermophilic hydrogen-producing bacterium from buffalo-dung. Extremophiles. 2010 Mar;14(2):233–40. doi: 10.1007/s00792-010-0303-x.