CAS: 959-66-0; N-Phenylbenzoylacetamide

该化合物是一种多用途有机化合物,其分子配方为C15H13NO2,通常用作制药和精美化学合成的中间体,其结构以苯并二甲二烯为特点,能够用于制作各种三环化合物和活性药物成分(APIs),产品具有很高的纯度和稳定性,适合精确的合成应用,在温和条件下的活性允许有效衍生,有助于其在染料,农用化学品和药剂开发中的作用. 2-苯并氯二烯二烯因其一贯性能和与一系列反应条件的兼容性而受到重视.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号201230-82-2 carbon monoxide | CAS号3282-32-4 2-二氮杂-1-苯乙酮 | CAS号94-02-0 苯甲酰乙酸乙酯 | CAS号100-52-7 苯甲醛 | CAS号614-20-0 苯甲酰乙酸 | CAS号103-71-9 异氰酸苯酯 | CAS号536-74-3 苯乙炔 | CAS号104705-39-7 1-oxido-4-oxo-N... | CAS号93-89-0 苯甲酸乙酯 | CAS号495-40-9 苯丁酮 | CAS号212517-39-0 1-Phenyl-2,4(1H... | CAS号93-98-1 N-苯甲酰替苯胺 | CAS号725-12-2 2,5-二苯基-1,3,4-噁二唑 | CAS号98-86-2 苯乙酮 | CAS号103-84-4 N-乙酰苯胺 | CAS号134-81-6 联苯甲酰 | CAS号102-07-8 |N|,|N|'-二苯基脲

合成工艺路线路线简述

  • 69857-80-3 = 959-66-0
    反应条件:1.1 Reagents: Hydrochloric Acid
    标题:Nucleophilic Behavior Of 1-Substituted Morpholino Ethenes
    作者:Ferri,R. A.; Pitacco,G.; Valentin,E.
    参考文献:Tetrahedron 日期:1978 卷标:34(16) 页码:2537-43]

    98-86-2 = 959-66-0
    反应条件:1.1 Reagents: Lithium Diisopropylamide Solvents: Diethyl Ether
    标题:New Synthesis Of β-Keto Amides Via Reaction Of Ketone Lithium Enolates With Isocyanates
    作者:Hendi,Shivakumar B.; Hendi,Mukta S.; Wolfe,James F.
    参考文献:Synthetic Communications 日期:1987 卷标:17(1) 页码:13-18]

    1236069-51-4 = 959-66-0
    反应条件:1.1 Reagents: Trifluoroacetic Acid Solvents: Trifluoroacetic Acid; 40 Min,Rt1.2 Reagents: Sodium Acetate Solvents: Water; Rt
    标题:Enamine-Based Domino Strategy For C-Acylation/deacetylation Of Acetoacetamides. A Practical Synthesis Of β-Keto Amides
    作者:Angelov,Plamen
    参考文献:Synlett 日期:2010 卷标:(8) 页码:1273-1275]

    94-02-0 = 959-66-0
    反应条件:1.1 Catalysts: 1-Butyl-3-Methylimidazolium Hydroxide Solvents: Toluene; 2 H,Reflux1.2 Reagents: Hydrochloric Acid Solvents: Water; 2 H,Rt
    标题:Selective Exploitation Of Acetoacetate Carbonyl Groups Using Imidazolium Based Ionic Liquids: Synthesis Of 3-Oxo-Amides And Substituted Benzimidazoles
    作者:Chakraborty,Ankita; Majumdar,Swapan; Maiti,Dilip K.
    参考文献:Tetrahedron Letters 日期:2016 卷标:57(30) 页码:3298-3302]

    614-20-0 = 959-66-0
    反应条件:1.1 Reagents: Dicyclohexylcarbodiimide Solvents: Dichloromethane; Rt
    标题:One-Pot Synthesis Of 3-Hydroxyquinolin-2(1H)-Ones From N-Phenylacetoacetamide Via Phi(Ococf3)2-Mediated α-Hydroxylation And H2So4-Promoted Intramolecular Cyclization
    作者:Yuan,Yucheng; Yang,Rui; Zhang-Negrerie,Daisy; Wang,Junwei; Du,Yunfei; Et Al
    参考文献:Journal Of Organic Chemistry 日期:2013 卷标:78(11) 页码:5385-5392]

    3282-32-4 = 959-66-0
    反应条件:1.1 Catalysts: Tris(Dibenzylideneacetone)Dipalladium Solvents: Toluene; 6 H,60 °C
    标题:Pd-Catalyzed Carbonylation Of Diazo Compounds At Atmospheric Pressure: A Catalytic Approach To Ketenes
    作者:Zhang,Zhenhua; Liu,Yiyang; Ling,Lin; Li,Yuxue; Dong,Yian; Et Al
    参考文献:Journal Of The American Chemical Society 日期:2011 卷标:133(12) 页码:4330-4341]

    98-86-2 = 959-66-0
    反应条件:1.1 Reagents: Lithium Diisopropylamide Solvents: Diethyl Ether; -78 °C; 25 Min,-78 °C1.2 Solvents: Diethyl Ether; -78 °C; 2 H,-78 °C -> Rt1.3 Reagents: Ammonium Chloride Solvents: Water; Rt
    标题:Scaffold Hopping Approach On The Route To Selective Tankyrase Inhibitors
    作者:Liscio,Paride; Carotti,Andrea; Asciutti,Stefania; Ferri,Martina; Pires,Maira M.; Et Al
    参考文献:European Journal Of Medicinal Chemistry 日期:2014 卷标:87 页码:611-623]

    94-02-0 = 959-66-0
    反应条件:1.1 Solvents: Dimethylformamide; 3 H,Reflux
    标题:Synthesis Of Some New Pyrazole,Pyrimidine,Pyridazine,And Their Fused Derivatives From 3-Oxo-3,N-Diphenylpropionamide
    作者:Abdelrazek,Fathy M.; Elkholy,Yehia M.; Salah,Ali M.; Abdelazeem,Nagwa M.; Metz,Peter
    参考文献:Journal Of Heterocyclic Chemistry 日期:2014 卷标:51(3) 页码:824-829]

    94-02-0 = 959-66-0 [标题:Reaction Conditions
    标题:Benzoylacetanilide
    作者:Allen,C. F. H.; Humphlett,W. J.
    参考文献:Organic Syntheses 日期:1957 卷标:37 页码:2-5]

    77092-12-7 = 959-66-0
    反应条件:1.1 3 Min,178 °C
    标题:An Efficient And Rapid Synthesis Of β-Carboxamide Derivatives,Using 2,2-Dimethyl-2H,4H-1,3-Dioxin-4-Ones,By Microwave Irradiation
    作者:Miriyala,Bruhaspathy; Williamson,John S.
    参考文献:Tetrahedron Letters 日期:2003 卷标:44(43) 页码:7957-7959]

    94-02-0 = 959-66-0
    反应条件:1.1 Catalysts: Sodium Ethoxide; Rt -> 130 °C; 6 - 12 H,120 - 130 °C
    标题:Preparation Method Of Benzoylacetanilide Organic Intermediate With High Purity And Yield From Ethyl Benzoylacetate And Aniline
    参考文献:China]

    94-02-0 = 959-66-0
    反应条件:1.1 Catalysts: Silver Triflate Solvents: Nitromethane; 8 H,80 °C
    标题:Silver(I)-Catalyzed Tandem Approach To β-Oxo Amides
    作者:Vandavasi,Jaya Kishore; Hsiao,Cheng-Tien; Hu,Wan-Ping; Boominathan,Siva Senthil Kumar; Wang,Jeh-Jeng
    参考文献:European Journal Of Organic Chemistry 日期:2015 卷标:2015(14) 页码:3171-3177]

    98-86-2 = 959-66-0
    反应条件:1.1 Reagents: Sodium Hydride Solvents: Toluene; Rt1.2 Rt; 1 - 3 H,Reflux1.3 Reagents: Ammonium Chloride Solvents: Water1.4 Reagents: Hydrochloric Acid Solvents: Water; Ph 7
    标题:Highly Enantioselective Epoxidation Catalyzed By Cinchona Thioureas: Synthesis Of Functionalized Terminal Epoxides Bearing A Quaternary Stereogenic Center
    作者:Russo,Alessio; Galdi,Gerardina; Croce,Gianluca; Lattanzi,Alessandra
    参考文献:Chemistry - A European Journal 日期:2012 卷标:18(20) 页码:6152-6157]

    94-02-0 = 959-66-0
    反应条件:1.1 Catalysts: 4-(Dimethylamino)Pyridine Solvents: Toluene; 1 H,150 °C
    标题:Cooperative Heterogeneous Organocatalysis And Homogeneous Metal Catalysis For The One-Pot Regioselective Synthesis Of 2-Pyridones
    作者:Allais,Christophe; Basle,Olivier; Grassot,Jean-Marie; Fontaine,Maxime; Anguille,Stephane; Et Al
    参考文献:Advanced Synthesis & Catalysis 日期:2012 卷标:354(11-12) 页码:2084-2088]

    94-02-0 = 959-66-0
    反应条件:1.1 Solvents: Xylene; Reflux; 4 H,Reflux
    标题:Synthesis,Characterisation,And Study Of The Photophysical Properties Of Highly Stable Imidazole-Based Novel Solid-State Fluorescent Azo Colourants
    作者:Moolya,Preetam N.; Gadilohar,Balu L.; Shankarling,Ganapati S.
    参考文献:Coloration Technology 日期:2015 卷标:131(2) 页码:104-109]

    614-16-4 + 10182-84-0 + 37181-39-8 = 959-66-0
    反应条件:1.1 Catalysts: Copper(Ii) Triflate Solvents: 1,2-Dichloroethane,Water; 12 H,80 °C
    标题:Chemoselective Cu-Catalyzed Synthesis Of Diverse N-Arylindole Carboxamides,β-Oxo Amides And N-Arylindole-3-Carbonitriles Using Diaryliodonium Salts
    作者:Kumar Mehra,Manish; Malik,Monika; Kumar,Bintu; Kumar,Dalip
    参考文献:Organic & Biomolecular Chemistry 日期:2021 卷标:19(5) 页码:1109-1114]

    98-80-6 + 621-03-4 = 959-66-0
    反应条件:1.1 Reagents: Trifluoroacetic Acid Catalysts: 2,2′-Bipyridine,Palladium Diacetate Solvents: Tetrahydrofuran; 22 - 30 H,80 °C
    标题:Palladium Catalyzed Hydrolysis-Free Arylation Of Aliphatic Nitriles For The Synthesis Of 4-Arylquinolin-2-One/pyrazolone Derivatives
    作者:Krishna Reddy,Singarajanahalli Mundarinti; Prasanna Kumari,Subramaniyan; Selva Ganesan,Subramaniapillai
    参考文献:Tetrahedron Letters 日期:2021 卷标:79]

    94-02-0 = 959-66-0 [标题:Reaction Conditions
    标题:Synthesis Of Ethyl Benzoylacetate
    作者:Zhang,Bin
    参考文献:Huaxue Tongbao 日期:1984 卷标:(9) 页码:22-3]

    77092-12-7 = 959-66-0 [标题:Reaction Conditions
    标题:Reaction Of 6-Aryl-2,2-Dimethyl-1,3-Dioxin-4-Ones With Aromatic Amines And O-Phenylenediamine
    作者:Andreichikov,Yu. S.; Gein,V. L.; Kozlov,A. P.; Vinokurova,O. V.
    参考文献:Zhurnal Organicheskoi Khimii 日期:1988 卷标:24(1) 页码:210-17]

    2579-22-8 + 100-65-2 = 959-66-0
    反应条件:1.1 Solvents: Tetrahydrofuran; 36 H
    标题:Catalyst- And Additive-Free Approach To Constructing Benzo-Oxazine,Benzo-Oxazepine,And Benzo-Oxazocine: O Atom Transfer And C=o,C-N,And C-O Bond Formation At Room Temperature
    作者:Ghosh,Arnab; Hegde,Rajeev V.; Rode,Haridas B.; Ambre,Ram; Mane,Manoj V.; Et Al
    参考文献:Organic Letters 日期:2021 卷标:23(21) 页码:8189-8193
📜苯甲羟肟酸置于potassium Tert-Butylate体系中,用 二氯甲烷,甲苯 作为反应溶剂,化学反应 0.5H,反应生成 2-苯甲酰乙酰苯胺
参考文献:1,4,2-二恶唑-5-酮作为异氰酸酯等价物:通过β-酮酰胺有效合成2-喹啉酮
标题:1,4,2-二恶唑-5-酮作为异氰酸酯等价物:通过β-酮酰胺有效合成2-喹啉酮
摘要:在热条件下,已知 1,4,2-Dioxazol-5-Ones 会先脱羧,然后发生 Lossen 重排,反应生成异氰酸酯.本文描述的是用碳亲核试剂原位捕获所得异氰酸酯以合成β-酮酰胺.此外,还报道了一种将所得 β-酮酰胺转化为喹啉-2-酮的通用且温和的方法.
DOI:10.1055/s-0040-1720889

海关参考信息

专利信息


专利号:US-5919969-A
优先权日:1996-06-05
标 题 :Synthesis of yellow couplers
发明人：CRAWLEY MICHAEL W
权利人:EASTMAN KODAK CO
摘要:The invention provides a method of synthesis of a image-dye forming coupler of formula (I) wherein X is a substituent linked to the coupler by an atom of oxygen, sulfur or nitrogen R1 is an alkyl or aryl group, R2 is a hydrogen atom or an alkyl group; R3 to R7 are the same or different and selected from a hydrogen atom and substituent groups; which method comprises the reaction of a compound of formula (II) wherein R and R1 are the same or different and are as defined above for R1 and X is as defined above with a compound of formula (III) wherein R2 to R7 are as defined above, in the presence of an inert organic solvent.

专利号:US-6159673-A
优先权日:1996-07-17
标 题:Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M is a cation. Other oxonol compounds, a light-sensitive material containing an oxonol compound and a process for the synthesis of an oxonol compound are also disclosed.

专利号:EP-1473330-B1
优先权日:1996-07-17
标题:Process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which each of Z, W<1> and W<2> independently is an atomic group that forms a heterocyclic ring; and M is a cation. A process for the synthesis of an oxonol compound is disclosed.

专利号:EP-1473330-A1
优先权日:1996-07-17
标题:Process for the synthesis of oxonol compound

专利号:EP-0819977-A1
优先权日:1996-07-17
标题 :Oxonol compound, silver halide photographic material and process for the synthesis of oxonol compound

专利号:DE-69737376-T2
优先权日:1996-07-17
标 题:Process for the synthesis of an oxonol compound

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Singh, F. V., Science of Synthesis Knowledge Updates, (2021) 1, 205.
摘要:Xu, L.; Wu, X.; Xiao, J., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 291.
摘要:Rodriguez, J.; Bonne, D.; Coquerel, Y.; Constantieux, T., Science of Synthesis: Multicomponent Reactions, (2013) 2, 1.
摘要:Rodriguez, J.; Bonne, D.; Coquerel, Y.; Constantieux, T., Science of Synthesis: Multicomponent Reactions, (2013) 2, 8.
摘要:C. A. Bishop and L. K. J. Tong, J. Phys. Chem. 66, 1034 (1962).
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知