CAS: 879-39-0; 2,3,4,5-Tetrachloronitrobenzene
该化合物是一种氯化硝化化合物,其分子式为C6HCl4NO2,其特点是存在四个氯原子和一个与苯环相连的硝基组,促使其在有机合成中具有高度的回活动性和实用性.该化合物由于电子抽取特性,通常被用作生产农用化学品,染料和药品的中间体,有助于进一步实现功能化.其稳定的芳香结构和可预测的再活动使其成为替代电子生物和核细胞迁移反应的有价值的试剂.由于它潜在的毒性和环境持久性,适当的处理是必不可少的.
- 相似结构搜索
- 产品信息参考
- InChIKey: MTBYTWZDRVOMBR-UHFFFAOYSA-N
- InChI=1S/C6HCl4NO2/c7-2-1-3(11(12)13)5(9)6(10)4(2)8/h1H
- 计算化学: 氢键受体数2.0氢键供体数*可旋转键数1.0
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别急性毒性 类别4(吸入)
急性毒性 类别4(经皮)
急性毒性 类别4(经口)
特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
皮肤致敏 类别1
水生急性毒性 类别1
水生慢性毒性 类别1 - 警示词Warning(警告)
- 危险描述H332 |吸入有害.
H312 |皮肤接触有害.
H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H317 |可能引起皮肤过敏反应.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响. - 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
- UN编号2811.0
- 危险品标志Xn
- 安全声明26-36/37/39-36
- 危险类别码20/21/22-36/37/38
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号634-66-2 1,2,3,4-四氯苯 | CAS号6627-34-5 2,5-二氯-4-硝基苯胺 | CAS号38411-17-5 N-(2,5-Dichloro... | CAS号62406-69-3 2,3,6-trichloro... | CAS号172215-92-8 2,3,4-trichloro... | CAS号611-06-3 2,4-二氯硝基苯 | CAS号40321-76-4 1,2,3,7,8-五氯二苯并对二恶英 | CAS号634-83-3 2,3,4,5-四氯苯胺 | CAS号15952-70-2 2,4-二氟-3,5-二氯硝基苯 | CAS号2691-93-2 1,2,3,4-tetrach... | CAS号781-15-7 1,2,3,4-四氯-5,6-二硝基苯 | CAS号654-36-4 2,3,4,6-tetrach...合成工艺路线路线简述
📜1,2,3,4-四氯苯置于二氧化氮,臭氧体系中,用 二氯甲烷 作为反应溶剂,化学反应 2.0H,反应生成 2,3,4,5-四氯硝基苯
参考文献:Ozone-Mediated Reaction Of Polychlorobenzenes And Some Related Halogeno Compounds With Nitrogen Dioxide: A Novel Non-Acid Methodology For The Selective Mononitration Of Moderately Deactivated Aromatic Systems
标题:Ozone-Mediated Reaction Of Polychlorobenzenes And Some Related Halogeno Compounds With Nitrogen Dioxide: A Novel Non-Acid Methodology For The Selective Mononitration Of Moderately Deactivated Aromatic Systems
摘要:在臭氧的存在下,最好使用美克磺酸作为催化剂,聚氯苯在低温下与二氧化氮选择性地单硝化,得到相应的聚氯硝基苯,在大多数情况下,几乎以定量产率得到.
DOI:10.1055/s-1994-25586
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-4517129-A
优先权日:1983-02-15
标 题 :Process for the preparation of cyanotetrachlorobenzenes
发明人：MILNER DAVID J
权利人:ICI PLC
摘要:Cyanotetrachlorobenzenes, especially ortho- and para- dicyanotetrachlorobenzenes, are prepared by reacting in a liquid medium at 20 DEG -100 DEG C. a corresponding nitrotetrachlorobenzene with, in solution, an inorganic cyanide. Preferably the liquid medium is a two-phase water/water-immiscible organic solvent system, e.g. water/chloroform, a phase transfer catalyst is present and the inorganic cyanide is an alkali metal or alkaline earth metal cyanide. The compounds are useful chemical intermediates in the synthesis of, for instance, pesticidal compounds.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 7-4, 7-5, 8-12 (1990)
摘要:White-Stevens, R. (ed.). Pesticides in the Environment: Volume 1, Part 1, Part 2. New York: Marcel Dekker, Inc., 1971., p. 18
摘要:Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 14th Edition. John Wiley & Sons, Inc. New York, NY 2001., p. 713
摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)
摘要:Mill T et al; Environmental Fate and Exposure Studies Development of a PC-SAR for Hydrolysis: Esters, Alkyl Halides and Epoxides. EPA Contract No. 68-02-4254. Menlo Park, CA: SRI International (1987)
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