CAS: 6940-78-9; 1-Bromo-4-Chlorobutane

相似化合物

54512-75-3 6294-17-3 110-52-1

上下游产品

CAS号30379-55-6 苄氧乙酸 | CAS号109-70-6 1-溴-3-氯丙烷 | CAS号928-51-8 4-氯-1-丁醇 | CAS号109-65-9 正溴丁烷 | CAS号110-56-5 1,4-二氯丁烷 | CAS号6334-96-9 双(4-氯丁基)醚 | CAS号109-99-9 四氢呋喃 | CAS号109-69-3 1-氯丁烷 | CAS号7782-50-5 氯气 | CAS号7791-25-5 磺酰氯 | CAS号107355-86-2 [5-(5-chloropen... | CAS号104605-71-2 methyl 4-(4-chl... | CAS号4830-93-7 1-氯-4-苯基丁烷 | CAS号14467-68-6 1-nitro-4-[4-(4... | CAS号14467-62-0 1-(4-nitropheno... | CAS号36865-43-7 4-乙氧基氯丁烷 | CAS号927-73-1 4-氯-1-丁烯 | CAS号929-21-5 7-氯-1-庚烯 | CAS号21098-11-3 8-(4-氯丁基)-8-氮杂螺... | CAS号18719-44-3 2-(4-氯丁基)丙二酸二乙酯

1,4-二氯丁烷置于1,4-二溴丁烷,四丁基溴化铵体系中,化学反应 19.5H,以49.7%的收率获得产物1-溴-4-氯丁烷
参考文献:Homogeneous Nucleophile Exchange. 1. Simple,High-Yield Synthesis Of Some Heterodihalides
标题:Homogeneous Nucleophile Exchange. 1. Simple,High-Yield Synthesis Of Some Heterodihalides
摘要:
DOI:10.1021/jo00241A045

专利信息

专利号:US-4026911-A
优先权日:1976-02-23
标 题:Process for the preparation of ketoalkynoic acids and use of the process in an improved synthesis of 2-(substituted)-cyclo-pentane-1,3,4-triones
发明人：REVERMAN LAWRENCE FRANCIS
权利人:MILES LAB
摘要:Reaction of a 2-methyl-2-(alkenyl)-1,3-dioxolane with an α,ω-dihalogenoalkane to obtain a 2-methyl-2-(ω-chloroalkynyl)-dioxolane, conversion of the latter to a corresponding nitrile, and hydrolysis of the nitrile to form a ketoalkynoic acid is a novel process for preparing the acid. n Use of the process in the synthesis of 2-(substituted)-cyclopentane-1,3,4-triones improves that synthesis.

专利号:US-2007149782-A1
优先权日:2005-12-23
标 题:Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of Aripiprazole
发明人：BRAND MICHAEL; SHOOKRUN MOTY; GRIBUN IRINA; ADIN ITAI; IUSTAIN CARMEN; BRAVERMAN OLEG; UDIS NATALIA; ARAD ODED; KASPI JOSEPH
权利人:BRAND MICHAEL; SHOOKRUN MOTY; GRIBUN IRINA; ADIN ITAI; IUSTAIN CARMEN; BRAVERMAN OLEG; UDIS NATALIA; ARAD ODED; KASPI JOSEPH
摘要:The present invention relates to methods of preparing a highly pure crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone, which is a chemical intermediate useful in the preparation of Aripiprazole thereof in high quality and yield, and provides data that characterizes the crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-(1H)-quinolinone.

专利号:US-12006301-B1
优先权日:2021-05-13
标题 :And synthesis of dual 5-HT1A and 5-HT7 receptor ligands
发明人：ABLORDEPPEY SETH Y
权利人:FLORIDA A&M UNIV
摘要:Novel dual 5-HT1A and 5-HT7 receptor ligands and methods of using the novel ligands to treat a neurological disorder are presented.

专利号:US-6989401-B2
优先权日:2000-07-19
标题:Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products
发明人：MAEDA KAZUHIRO; SONDA SHUJI; TAKEMOTO TADAHIRO; GOTO TOMOKAZU; KOBAYASHI FUJIO; KAJII MASAHIKO; KOMORITA NARUYASU; HIRAYAMA FUMIHIRO
权利人:MITSUBISHI PHARMA CORP
摘要:The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof, which is useful as an inhibitor of lipopolysaccharides (LPS). In addition, the present invention relates to a novel intermediate compound useful for the synthesis of this sulfonic acid derivative of hydroxamic acid.

专利号:US-5232929-A
优先权日:1990-11-28
标 题 :3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
发明人：DESAI MANOJ C; ROSEN TERRY J
权利人:PFIZER
摘要:The present invention relates to novel 3-aminopiperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , Y and m are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of the formula I.

专利号:WO-2007072476-A2
优先权日:2005-12-23
标题 :Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of aripiprazole