CAS: 640-61-9; N,4-Dimethylbenzenesulfonamide

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CAS号1634-04-4 甲基叔丁基醚 | CAS号70-55-3 对甲苯磺酰胺 | CAS号3558-60-9 甲基苯乙基醚 | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号74-89-5 氨基甲烷 | CAS号824-79-3 对甲苯亚磺酸钠 | CAS号80-11-5 N-甲基-N-亚硝基对甲苯磺酰胺 | CAS号120-72-9 吲哚 | CAS号591-50-4 碘苯 | CAS号1099-76-9 Benzenesulfonam... | CAS号21230-34-2 N-(2-cyanoethyl... | CAS号23114-01-4 N,4-dimethyl-N-... | CAS号22547-51-9 Benzenesulfonic... | CAS号273208-11-0 2-iodo-N,4-dime... | CAS号26862-22-6 N,4-dimethyl-N-... | CAS号88303-12-2 4-甲苯基-N-氟-N-甲基磺胺 | CAS号80-48-8 对甲苯磺酸甲酯 | CAS号80-11-5 N-甲基-N-亚硝基对甲苯磺酰胺 | CAS号36323-18-9 3-butyl-1-methy...

N-甲基-N-亚硝基对甲苯磺酰胺置于氢气,β-环糊精体系中,用 水,乙腈 作为反应溶剂,化学反应生成 N-甲基对甲苯磺酰胺
参考文献:β-环糊精-胶束混合体系作为反应介质.n-甲基-N-亚硝基对甲苯磺酰胺的脱硝化
标题:β-环糊精-胶束混合体系作为反应介质.n-甲基-N-亚硝基对甲苯磺酰胺的脱硝化
摘要:在含有不同阳离子胶束聚集体(月桂基三甲基溴化铵,十四烷基三甲基溴化铵和十六烷基三甲基氯化铵)和 β-环糊精 (β-Cd) 的介质中研究了 N-甲基-N-亚硝基-对甲苯磺酰胺 (Mnts) 的酸水解动力学.结果用伪相模型解释.该模型考虑了 β-Cd-表面活性剂和 β-Cd-Mnts 复合物的形成.β-Cd 的存在对现有胶束没有影响,但会提高 Cmc.β-Cd 与表面活性剂的络合使 Cmc 依赖于 β-Cd 浓度,因为 Cmc 现在是胶束开始形成时游离和络合表面活性剂浓度的总和.在高于 Cmc 的表面活性剂浓度下,胶束化和络合过程之间的竞争导致存在显着浓度的游离环糊精.版权所有 © 2000 John Wiley & Sons,Ltd.
DOI:10.1002/1099-1395(200010)13:10<664::Aid-Poc264>3.0.Co;2-U

专利信息

专利号:US-9708317-B2
优先权日:2013-11-25
标 题 :Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivatives
发明人：ZAMBON ALFONSO; NICULESCU-DUVAZ DAN; CHUBB RICHARD; SPRINGER CAROLINE JOY
权利人:CANCER RES TECH LTD; INST OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE); OXY SCIENT LTD; THE INST OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
摘要:The present invention pertains generally to the field of organic chemical synthesis, and in particular to certain methods for the synthesis of 8-(4-aminophenyoxy)-4H-pyrido[2,3-b]pyrazin-3-one and related compounds (denoted herein as (3)) from 4-(4-aminophenyoxy)pyridine-2,3-diamine and related compounds (denoted herein as (1)), by reaction with glyoxylic acid (denoted herein as (2)). The compounds (3) are useful in the synthesis of known anti-cancer agents, such as 1-(5-tert-butyl-2-(4-methyl-phenyl)-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea.

专利号:US-8779207-B2
优先权日:2012-08-31
标题 :Method for synthesis of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) and fullerene derivatives
发明人：NG KA MING; ZHUANG JIANLE; TSENG NAI WEN; YU YONG
权利人:NG KA MING; ZHUANG JIANLE; TSENG NAI WEN; YU YONG; NANO & ADVANCED MATERIALS INST LTD
摘要:The present subject matter relates to methods for the synthesis of [6,6]-phenyl-C 61 -butyric acid methyl ester (PCBM) and fullerene derivatives in a yield of at least 40%.

专利号:US-12180182-B2
优先权日:2021-12-01
标题 :(Di)amination of activated allene compounds, derivatives thereof, and methods for synthesis of the same
发明人：DAI MINGJI
权利人:PURDUE RESEARCH FOUNDATION
摘要:One-pot synthesis methods for producing amines from activated allenes and derivatives thereof are provided, as well as the compounds produced thereby.

专利号:US-2009162290-A1
优先权日:2005-09-09
标 题 :Method for the synthesis of penta-pendant enantiomer-pure chelators and process for therapeutically active bioconjugates preparation by a covalent binding thereof
发明人：BENES IVAN; CIHELNIK SIMON; DROZ LADISLAV; SRAMEK MARTIN
权利人:THERAPHARM GMBH
摘要:The present invention provides a method for synthesis and binding methods of pentapendant enantiomer-pure chelators of formula (VII) wherein R 1 , R 2 , R 3 , R 4 are groups forming an adequate enantiomer of the chelator; and X 1 -X 5 , Y 1 -Y 5 , Z 1 -Z 5 each individually forming pendant chelating groups.

专利号:US-8981092-B2
优先权日:2008-09-19
标题 :Substituted 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-ones as modulators of protein kinase activity
发明人：MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO
权利人:MIRIZZI DANILO; CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; FERGUSON RON; CASUSCELLI FRANCESCO; NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds, n nor pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

专利号:US-RE41614-E
优先权日:1998-09-30
标题 :Synthetic analogs of ecteinascidin-743
发明人：COREY ELIAS J
权利人:HARVARD COLLEGE
摘要:The present invention is directed to the synthesis and characterization of compounds having the formula: n n wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are each independently selected from the group consisting of H, OH, OR′, SH, SR′, SOR′, SO 2 R′, NO 2 , NH 2 , NHR′, N(R′) 2 , NHC(â•?O)R′ NHC( â•?O ) R′ , CN, halogen, â•?O, C(â•?O)H, C(â•?O)R′, CO 2 H, CO 2 R′, C 1 -C 12 alkyl, C 2 -C 12 alkenyl, C 2 -C 12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, and substituted or unsubstituted heteroaromatic; wherein each of the R′ groups is independently selected from the group consisting of H, OH, NH 2 , NO 2 , SH, CN, halogen, â•?O, C(â•?O)H, C(â•?O)CH 3 , CO 2 H, CO 2 CH 3 , C 1 -C 12 alkyl, C 2 -C 12 alkenyl, C 2 -C 12 alkynyl, aryl, aralkyl, and heteroaromatic; wherein each dotted circle represents one, two or three optional double bonds; wherein R 7 and R 8 may be are joined into a carbocyclic or heterocyclic ring system; and wherein X 1 and X 2 are each independently defined as above for R 1 -R 8 R 1 - R 6 and R 9 , an each further includes specific preferred groups as defined herein.