CAS: 6302-02-9; 1-(Pyridin-2-yl)Propan-2-One

该化合物是一种有机化合物,其特征为环和氯酮功能组,典型的是一种黄色至褐色液体,具有独特的芳香味,该化合物在乙醇和乙醚等有机溶剂中溶解,但由于其水中具有疏水性,溶解性有限,该化合物在水中呈现一种分子配方,该分子配方表明存在一种碳基类,该碳基组与氮相邻,有助于其作为皮丝和化学协调体的再活性和潜力. 1-2-(2-丙烯基)-2-丙酮经常用于有机合成,特别是用于制作各种药品和农用化学品.此外,该化合物可参与各种化学反应,包括凝聚和氧化,使其成为合成有机化学中有价值的中间体.在处理该化合物时,应注意安全防范措施,因为如果吸入或浸入,可能会对健康造成危害.

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5307-19-7 65702-08-1 42508-80-5

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pyridine 2-(Trimethylsilyloxy)propene 2-chloropyridine acetone 1-(methyl-2-pyridin-2-ylethyl)amine 3-methyl-6-[2]pyridyl-cyclohex-2-enone N-methylpelletierine 3,5-diphenyl-6-[2]pyridyl-cyclohex-2-enone

合成工艺路线路线简述

    📜碳酸甲丙酯置于盐酸,正丁基锂体系中,用 四氢呋喃,正己烷,异丁酰胺,水,乙酸乙酯 作为反应溶剂,化学反应生成 1-吡啶-2-基-2-丙酮
    参考文献:Novel Compounds
    标题:Novel Compounds
    摘要:这项发明涉及到式(I)的杂环芳香族羧酰胺,其中a,R1,R2和x如规范中定义,以及用于它们制备的过程和中间体,含有它们的药物组合物以及它们在治疗中的应用.

    海关参考信息

    专利信息


    专利号:US-6281245-B1
    优先权日:1996-10-28
    标 题:Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
    发明人:PATEL DINESH V; NGU KHEHYONG
    权利人:VERSICOR INC
    摘要:A novel method for generating hydroxylamine, hydroxamic acid, hydroxyurea, and hydroxylsulfonamide compounds is disclosed. The method involves the nucleophilic attack of an alkoxyamine on a suitable solid phase support. Techniques of combinatorial chemistry can then be applied to the immobilized alkoxyamine to generate a diverse set of compounds. Cleavage of the compounds from the support yields a library of hydroxylamine or hydroxylamine derivative compounds, which can be screened for biological activity (e.g., inhibition of metalloproteinases).

    专利号:US-6541276-B2
    优先权日:1996-10-28
    标题:Methods for solid-phase synthesis of hydroxylamine compounds and derivatives and combinatorial libraries thereof
    发明人:PATEL DINESH V; NGU KHEHYONG
    权利人:VERSICOR INC
    摘要:A novel method for generating hydroxylamine, hydroxamic acid, hydroxyurea, and hydroxylsulfonamide compounds is disclosed. The method involves the nucleophilic attack of an alkoxyamine on a suitable solid phase support. Techniques of combinatorial chemistry can then be applied to the immobilized alkoxyamine to generate a diverse set of compounds. Cleavage of the compounds from the support yields a library of hydroxylamine or hydroxylamine derivative compounds, which can be screened for biological activity (e.g., inhibition of metalloproteases).

    专利号:CN-1081180-A
    优先权日:1992-07-10
    标题:Synthesis of Hydrazine Hydrate by Catalyzed Oxidation of Ammonia Sodium Hypochlorite

    专利号:US-5252309-A
    优先权日:1991-06-12
    标 题 :Azine synthesis in the absence of CO2
    发明人:KREMPF GERARD; COLLIER BERTRAND; TELLIER PIERRE; SCHIRMANN JEAN-PIERRE
    权利人:ATOCHEM ELF SA
    摘要:Azines, well suited for hydrolysis into hydrazine, are prepared in high yields by reacting ammonia, aqueous hydrogen peroxide and a carbonyl compound reactant in the presence of a catalytically effective amount of a catalyst medium therefor, i.e., an aqueous solution of ammonium acetate and acetamide or of acetamide and acetic acid, but in the absence of CO 2 .

    专利号:US-2001053555-A1
    优先权日:1996-10-28
    标题 :Methods for solid-phase synthesis of hydroxylamine compounds and derivatives and combinatorial libraries thereof

    专利号:CN-101234996-B
    优先权日:2008-02-29
    标题:A kind of green synthesis method of ketazine

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Hari, Y.; Aoyama, T.; Shioiri, T., Science of Synthesis Knowledge Updates, (2010) 4, 30.
    摘要:Balzer, J.; Tost, M.; Gulder, T., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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