CAS: 52757-95-6; Sevelamer

📜盐酸司维拉姆,Sodium Hydroxide 反应 1.0H,反应生成 司维拉姆
参考文献:Process For Preparation Of Sevelamer Carbonate
标题:Process For Preparation Of Sevelamer Carbonate
摘要:本发明公开了一种简单的制备聚烯丙胺聚合物盐的过程.

专利信息

专利号:US-2017283878-A1
优先权日:2015-12-11
标题:Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
发明人：WONG CHI-HUEY; WU CHUNG-YI; CHEUNG SARAH K C; CHUANG PO-KAI; HSU TSUI-LING
权利人:ACADEMIA SINICA
摘要:The present disclosure relates to methods and compositions which can modulate the globoseries glycosphingolipid synthesis. Particularly, the present disclosure is directed to glycoenzyme inhibitor compound and compositions and methods of use thereof that can modulate the synthesis of globoseries glycosphingolipid SSEA-3/SSEA-4/GloboH in the biosynthetic pathway; particularly, the glycoenzyme inhibitors target the alpha-4GalT; beta-4GalNAcT-I; or beta-3GalT-V enzymes in the globoseries synthetic pathway. Additionally, the present disclosure is also directed to vaccines, antibodies, and/or immunogenic conjugate compositions targeting the SSEA-3/SSEA-4/GLOBO H associated epitopes (natural and modified) which elicit antibodies and/or binding fragment production useful for modulating the globoseries glycosphingolipid synthesis. Moreover, the present disclosure is also directed to the method of using the compositions described herein for the treatment or detection of hyperproliferative diseases and/or conditions. Furthermore, the instant disclosure also relates to cancer stem cell biomarkers for diagnostic and therapeutic uses.

专利号:EP-1616964-B1
优先权日:2004-06-30
标 题 :Process for preparative in vitro protein biosynthesis
发明人：STREY JAN DR; MERK HELMUT DR; STIEGE WOLFGANG DR
权利人:QIAGEN GMBH
摘要:Preparative in vitro synthesis of an expression product (I) in a cell-free transcription and translation system (A). Preparative in vitro synthesis of an expression product (I) in a cell-free transcription and translation system (A) comprises: (A) filling a reaction vessel with a solution containing components of (A) for a selected (I), amino acids and metabolic components that provide energy and are required for synthesis of (I); (B) performing synthesis of (I) for a predetermined time (T), without separation of substances formed and without addition of consumed synthesis substrates; (C) after expiry of T, low molecular weight metabolic products and/or reaction inhibitors are removed from solution; (D) immediately before, after or during step (c), the synthesis components that have been consumed are replaced; and (E) steps (b)-(d) are repeated, at least once, and in the last cycle, steps (c) and (d) may be omitted. An independent claim is also included for a similar method in which the reaction vessel may also include a system (A') for synthesis of a second, different product (I'), plus amino acids and required metabolic components; step (b) is as above; step (c) is omitted and step (d) is similar but includes addition of (A'), if not already present, and the final step is synthesis of (I') for a predetermined time, with separation of substances formed or addition of consumed synthesis substrates.

专利号:CN-108434151-A
优先权日:2008-01-11
标题 :Synthesis of triterpenoids and method for treating diseases

专利号:CN-102675510-A
优先权日:2012-05-28
标 题 :Synthesis of Sevelamer

专利号:CN-104739841-B
优先权日:2008-01-11
标题:Synthesis of triterpenoids and method for treating diseases

专利号:US-2007148246-A1
优先权日:2005-08-11
标题:Nucleic Acid-Based Matrixes
发明人：LUO DAN; LI YOUGEN
权利人:LUO DAN; LI YOUGEN
摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include delivery of biologically active agents, cell and tissue culture, and cell-free protein synthesis.