CAS: 52522-99-3; 5-Iodo-2,4-Dimethoxypyrimidine

该化合物是一种环状的杂交有机化合物,其特征是:六人组成的芳香环,含有1和3号位置的两个氮原子;2和4号位置的5个位置组和甲氧基组中存在碘有助于其独特的化学特性;该化合物一般在室内温度下是固体,在有机溶剂中可能表现出中等溶解性;其结构表明,由于碘原子的存在,它有可能产生反应,并可能参与核分裂性替代反应;甲氧基组可能影响该化合物的电子特性和阻力,影响其与其他分子的再活动与互动. 5-Iodo-2,4-甲氧基苯丙胺可能对医药化学和物质科学感兴趣,特别是制药或农用化学物的开发,因为其潜在的生物活动以及作为合成途径的建筑块体的能力.

结构式图片

相似化合物

219915-13-6 3551-55-1 4330-22-7

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报

上下游产品

2,4-dimethoxypyrimidine 5-Acetoxymercuri-2,4-dimethoxypyrimidine 5,5'-Mercuri-bis-(2,4-dimethoxypyrimidine) methanol 5-(2-benzoylethynyl)-2,4-dimethoxypyrimidine 5-(3-hydroxy-3-phenylprop-1-ynyl)-2,4-dimethoxypyrimidine pyrimidine2,4-dimethoxy-5-2-(p-methoxybenzoyl)ethynylpyrimidine 1,2-dihydro-5-iodo-4-methoxy-2-oxo-1-(2'-benzoyloxyethoxymethyl)pyrimidine

合成工艺路线路线简述

    📜2,4-二甲氧基嘧啶置于n-碘代丁二酰亚胺体系中,用35%的收率获得产物2,4-二甲氧基-5-碘嘧啶
    参考文献:Synthesis Of Substituted 5-(3-Oxobutyl)Pyrimidines Via Palladium-Catalyzed Coupling Reactions Of Iodopyrimidines With Methyl Vinyl Ketone
    标题:Synthesis Of Substituted 5-(3-Oxobutyl)Pyrimidines Via Palladium-Catalyzed Coupling Reactions Of Iodopyrimidines With Methyl Vinyl Ketone
    摘要:研究了几种取代卤嘧啶与醋酸双苯基磷酸钯-酮复合物在三乙胺存在下与甲基乙烯反应的情况.在溴嘧啶的反应中,获得了通常的烯烃取代产物.但使用碘嘧啶时,嘧啶与甲基乙烯酮的碳碳双键发生加成,反应生成取代的5-(3-氧代丁基)嘧啶.提出了可能的反应机制.
    DOI:10.1055/s-1988-27703

    海关参考信息

    专利信息


    专利号:WO-2021062168-A1
    优先权日:2019-09-25
    标 题 :Synthetic sphingolipid inspired molecules with heteroaromatic appendages, methods of their synthesis and methods of treatment
    发明人：EDINGER AIMEE; HANESSIAN STEPHEN
    权利人:UNIV CALIFORNIA; UNIV MONTREAL
    摘要:Small molecules compounds and methods of their synthesis are provided. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, neoplasms, cancers, and other diseases. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.

    专利号:WO-2024185814-A1
    优先权日:2023-03-06
    标题:Method for producing aryl compound containing tritylsulfanyl group
    发明人：OKAZOE TAKASHI; NOZAKI KYOKO; GATZENMEIER Tim; LIU YUE
    权利人:AGC INC; UNIV TOKYO
    摘要:The present invention provides: a substrate for achieving the highly efficient synthesis of an aryl compound containing a tritylsulfanyl group; a method for producing a compound containing an SF 5 group using the substrate; and others. The present invention is a method for producing an aryl compound containing a tritylsulfanyl group, the method comprising thiotritylating a halogenated aryl compound represented by general formula (1) [wherein A 1 represents an aryl group that may have a substituent or a heteroaryl group that may have a substituent; and X represents a halogen atom] using [(triphenylmethyl)sulfanyl]potassium or [(triphenylmethyl)sulfanyl]sodium to produce an aryl compound containing a tritylsulfanyl group, the aryl compound being represented by general formula (2) [wherein A 1 is the same as A 1 in general formula (1); and Ph represents a phenyl group].

    专利号:WO-2016123318-A2
    优先权日:2015-01-30
    标题:Design synthesis and methods of use of acyclic fleximer nucleoside analogues having anti-coronavirus activity

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 358.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知