氯酯醒置于三乙胺体系中,用 氯仿 作为反应溶剂,以78%的收率获得产物甲氯芬酯 参考文献:Esterquat Herbicidal Ionic Liquids (Hils) With Two Different Herbicides: Evaluation Of Activity And Phytotoxicity 标题:Esterquat Herbicidal Ionic Liquids (Hils) With Two Different Herbicides: Evaluation Of Activity And Phytotoxicity 摘要:新型除草剂控制剂,以两种不同的除草剂作为阳离子和阴离子的形式. DOI:10.1039/c8Nj01239C
专利号:US-7300639-B2 优先权日:2002-12-03 标 题:Process for removing metals from liquids 发明人:LIU WANSHENG 权利人:BRISTOL MYERS SQUIBB CO 摘要:A process is provided for removing one or more metals from liquids. Also provided is a process for the synthesis of aP2 inhibiting compounds having the formula (I) n nwherein R 1 , R 2 , R 3 , R 4 , HET, and X-Z are as described herein, which process comprising the step of removing one or more metals from a solution of the compound of formula I or an intermediate or precursor thereof. The processes for removing metal comprise the step of contacting the liquid with a solid extractant comprising a metal-binding functionality.
专利号:US-2009176740-A1 优先权日:2007-11-30 标题:Treatment of neurological conditions by the co-administration of aniracetam and l-alpha glycerylphosphorylcholine 发明人:PHILLIPS II DAUGLAS JAMES 权利人:PHILLIPS II DAUGLAS JAMES 摘要:Aniracetam (1-[(4-methoxybenzoyl)]-2-pyrrolidinone) is co-administered with the acetylcholine precursor 1-alpha glycerylphosphorylcholine (Alpha GPC, choline alfoscerate, choline alphoscerate) to potentiate cognition enhancing effects in healthy subjects and patients suffering from neurological conditions including Alzheimer's Disease (AD), attention deficit disorder (ADD), Parkinson's Disease, schizophrenia, vascular dementia, post stroke aphasia, anxiety disorders, cerebral atrophy, chronic alcoholism, Down syndrome, dyslexia, and various other neurodegenerative conditions. The co-administration of aniracetam (and other racetam derivatives including oxiracetam) with the acetylcholine precursor 1-alpha glycerylphosphorylcholine decreases negative side-effects such as severe headaches while increasing the synthesis and release of the neurotransmitters acetylcholine and glutamate to facilitate proper brain functioning.
专利号:WO-2010081731-A4 优先权日:2009-01-14 标 题 :Derivatives of syringolin a 发明人:KAISER MARKUS; CLERC JEROME 权利人:MAX PLANCK GESELLSCHAFT; KAISER MARKUS; CLERC JEROME 摘要:The present invention relates to syringolin A derivatives, the use of the syringolin A derivatives for prophylaxis and treatment of neurodegenerative diseases and proliferative diseases such as cancer, pharmaceutical compositions containing at least one syringolin A derivative as well as to a synthesis for preparing the syringolin A derivatives.
1: El-Nashar RM, Abdel Ghani NT, Hassan SM. Construction and performance characteristics of new ion selective electrodes based on carbon nanotubes for determination of meclofenoxate hydrochloride. Anal Chim Acta. 2012 Jun 12;730:99-111. doi: 10.1016/j.aca.2011.10.069. Epub 2011 Nov 15. German. German. Japanese. doi: 10.1016/j.clinthera.2008.09.013.
合成参考文献
参考文献:10.1007/s10545-011-9375-8 摘要:Breuer ME, Willems PHGM, Russel FGM, Koopman WJH, Smeitink JAM. Modeling mitochondrial dysfunctions in the brain: from mice to men. J of Inher Metab Disea. 2011 Jul 14;35(2):193–210. doi: 10.1007/s10545-011-9375-8.