CAS: 394-04-7; 5-Fluoro-2-Methoxybenzoic Acid

上下游产品

CAS号459-60-9 4-氟苯甲醚 | CAS号445-82-9 5-氟-2-甲氧基苯乙酮 | CAS号394-32-1 5-氟-2-羟基苯乙酮 | CAS号399-54-2 4-氟-2-甲基苯甲醚 | CAS号452-71-1 4-氟-2-甲基苯胺 | CAS号452-72-2 4-氟-2-甲基苯酚 | CAS号917-54-4 甲基锂 | CAS号109-72-8 正丁基锂 | CAS号60-29-7 乙醚 | CAS号124-38-9 二氧化碳 | CAS号345-16-4 5-氟水杨酸 | CAS号704-03-0 5-Fluoro-2-meth... | CAS号443-12-9 5-氟-2-羟基苯甲酸乙酯

对氟苯甲醚置于二硫化碳,三氯化铝,Sodium Hypobromide体系中,化学反应生成 5-氟-2-甲氧基苯甲酸
参考文献:Some Syntheses From P-Fluoroanisole
标题:Some Syntheses From P-Fluoroanisole
摘要:
DOI:10.1021/jo01375A009

专利信息

专利号:US-9688644-B2
优先权日:2009-04-30
标 题 :Synthesis of Tetracyclines and intermediates thereto
发明人：MYERS ANDREW G; KUMMER DAVID A; LI DERUN; HECKER EVAN; DION AMELIE; WRIGHT PETER M
权利人:HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

专利号:WO-2010126607-A2
优先权日:2009-04-30
标 题:Synthesis of tetracyclines and intermediates thereto

专利号:US-2016002183-A1
优先权日:2009-04-30
标 题:Synthesis of tetracyclines and intermediates thereto

专利号:US-2012115818-A1
优先权日:2009-04-30
标题:Synthesis of tetracyclines and intermediates thereto

专利号:EP-2424834-A2
优先权日:2009-04-30
标题:Synthesis of tetracyclines and intermediates thereto

专利号:US-9073829-B2
优先权日:2009-04-30
标 题 :Synthesis of tetracyclines and intermediates thereto