CAS: 216766-13-1; 5-Methoxy-2-(Trifluoromethyl)Pyridine

相似化合物

216766-12-0 1806767-74-7 1184172-41-5

上下游产品

sodium methylate 5-bromo-2(trifluoromethyl)pyridine 2,5-dibromopyridine 2-iodo-5-bromopyridine 5-methoxy-2-trifluoromethyl-pyridine-4-carbaldehyde 4-propyl-6-trifluoromethyl-pyridin-3-ol {2-methyl-4-[3-(4-propyl-6-trifluoromethyl-pyridin-3-yloxy)-propoxy]-phenoxy}-acetic acid methyl ester

2,5-二溴吡啶置于potassium Fluoride,Copper(L) Iodide,氢碘酸体系中,用 N-甲基吡咯烷酮,N,N-二甲基甲酰胺 用作溶剂,化学反应 38.0H,反应生成5-甲氧基-2-三氟甲基吡啶
参考文献:Studies Towards The Conception Of New Selective Pparβ/δ Ligands
标题:Studies Towards The Conception Of New Selective Pparβ/δ Ligands
摘要:In Order To Define New Ppar Beta/delta Ligands,Sar Study On The Selective Ppar Beta/delta Activator L-165,041 Led To The Identification Of One Key Functional Group For Selective Ppar Beta/delta Activation. Further-More,Taking Advantage Of Sar Studies Done Elsewhere On The Most Selective Ppar Beta/delta Ligand Gw501516,The Conception Of New Ligands Showing Good Affinity For Ppar Beta/delta Is Reported. Finally,Synthesis And Biological Evaluation Of Pyridine Analogues Have Shown The Benefical Effect Of The Pyridine Ring On The Ppar Beta/ Delta Subtype Selectivity. (C) 2006 Published By Elsevier Ltd.
Doi:10.1016/j.Bmcl.2006.06.028

专利信息

专利号:US-9745298-B2
优先权日:2015-05-06
标题:Synthesis of a compound that modulates kinases
发明人：IBRAHIM PRABHA N; JIN MASAYOSHI; MATSUURA SHINJI
权利人:PLEXXIKON INC; DAIICHI SANKYO CO LTD
摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nor a salt thereof, active on the receptor protein kinases c-Kit and/or c-Fms and/or Flt3. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.

专利号:US-2018305358-A1
优先权日:2015-05-06
标 题:Synthesis of a compound that modulates kinases

专利号:US-10399975-B2
优先权日:2015-05-06
标题:Synthesis of a compound that modulates kinases

专利号:US-10040792-B2
优先权日:2015-05-06
标 题 :Synthesis of a compound that modulates kinases

专利号:US-2017334909-A1
优先权日:2015-05-06
标 题:Synthesis of a compound that modulates kinases

专利号:US-2016326169-A1
优先权日:2015-05-06
标题 :Synthesis of a compound that modulates kinases