专利号:US-2024092787-A1 优先权日:2022-08-24 标 题:Pharmaceutical process and intermediates 发明人:GRAHAM MARK ANDREW; CARNEY JONATHAN ROBERT; BISHOP THOMAS GEORGE; COOPER KATIE 权利人:ASTRAZENECA AB 摘要:There is provided a new and improved synthetic route for the synthesis of the compound 1-{2-[(1R)-1-aminoethyl]-4-chlorobenzyl}-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one (Formula (I)) that is readily scalable for commercial production.Also provided are important intermediate compounds that are formed in the new and improved synthetic route for the synthesis of the compound of formula (I).
专利号:CN-114807249-A 优先权日:2022-03-25 标题 :A multi-enzyme cascade pathway for the synthesis of 2C or 4C compounds from CO2
专利号:CN-114540318-B 优先权日:2021-11-01 标题 :Enzyme with the function of catalyzing the synthesis of glycolic acid from glycolaldehyde and its application
专利号:RU-2012554-C1 优先权日:1989-01-24 标 题:Method of synthesis of benzocycloalkenyldihydrooxyalkanoic acid derivatives
专利号:CN-114807249-B 优先权日:2022-03-25 标题:Multi-enzyme cascade pathway that catalyzes the synthesis of 2C or 4C compounds from CO2
专利号:CN-114540318-A 优先权日:2021-11-01 标题:Enzyme with the function of catalyzing the synthesis of glycolic acid from glycolaldehyde and its application