CAS: 1360628-91-6; 3-Fluoro-4-(7-Methoxy-3-Methyl-8-(1-Methyl-1H-Pyrazol-4-yl)-2-Oxo-2,3-Dihydro-1H-Imidazo[4,5-C]Quinolin-1-yl)Benzonitrile

• 英文名称3-Fluoro-4-(7-Methoxy-3-Methyl-8-(1-Methyl-1H-Pyrazol-4-yl)-2-Oxo-2,3-Dihydro-1H-Imidazo[4,5-C]Quinolin-1-yl)Benzonitrile
• 中文名称3-氟-4-(7-甲氧基-3-甲基-8-(1-甲基-1H-H-4-基)-2-氧代-2,3-二氢-1H-咪唑并[4,5-C]喹啉-1-基)苯甲腈
• IUPAC名称3-fluoro-4-(7-methoxy-3-methyl-8-(1-methyl-1H-pyrazol-4-yl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)benzonitrile
• 其它别名Benzonitrile, 4-[2,3-Dihydro-7-Methoxy-3-Methyl-8-(1-Methyl-1H-Pyrazol-4-yl)-2-Oxo-1H-Imidazo[4,5-C]Quinolin-1-Yl]-3-Fluoro-; 4-[2,3-Dihydro-7-Methoxy-3-Methyl-8-(1-Methyl-1H-Pyrazol-4-yl)-2-Oxo-1H-Imidazo[4,5-C]Quinolin-1-Yl]-3-Fluorobenzonitrile; 3-Fluoro-4-(7-Methoxy-3-Methyl-8-(1-Methyl-1H-Pyrazol-4-yl)-2-Oxo-2,3-Dihydro-1H-Imidazo[4,5-C]Quinolin-1-yl)Benzonitrile
• CAS编号1360628-91-6
• 分子式:C23H17FN6O2分子量:428.43
• 产品CID: 562132
• 产品分类Inhibitors/Agonists → DNA Damage → ATM/ATR

• 相似结构搜索
• InChIKey: OOCGUVCGJIUQKC-UHFFFAOYSA-N
• InChI=1S/C23H17FN6O2/c1-28-12-14(10-27-28)15-7-16-18(8-21(15)32-3)26-11-20-22(16)30(23(31)29(20)2)19-5-4-13(9-25)6-17(19)24/h4-8,10-12H,1-3H3
• 计算化学: 氢键受体数*氢键供体数*可旋转键数*

物理性质

• 沸点634.8±65.0 °C(预测)
• 密度1.41±0.1 g/cm3(预测)
• pKa:5.36±0.20(预测)
• 外观形态类白色至淡黄色固体
• 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• 产品应用该化合物是一种强大的,具有ATP竞争力的和选择性的自动取款机抑制器,IC50为0.25纳米;它抑制双层断裂修复和显示抗振活动.

MSDS等安全信息

• 警示词Warning
• 危险描述H302-H315-H319-
• 防范说明P264-P270-P280-P301+P312+P330-P302+P352-P305+P351+P338-P332+P313-P337+P313-P501-

合成工艺路线路线简述

海关参考信息

• 2902300000-甲苯
  2905110000-甲醇
  2933310010-吡啶
  2908199090-其他酚的卤化衍生物
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管