74982-59-5 = 90921-11-2 反应条件:1.1 Reagents: Acetic Anhydride Catalysts: Sulfuric Acid Solvents: Acetic Acid,Acetic Anhydride 标题:Oxidative Substitution Reactions Of Organostannyl Compounds With Lead Tetraacetate. A Convenient Route To 5-Alkylidene-2(5H)-Furanones 作者:Yamamoto,Makoto; Munakata,Hiroshi; Kishikawa,Keiki; Kohmoto,Shigeo; Yamada,Kazutoshi 参考文献:Bulletin Of The Chemical Society Of Japan 日期:1992 卷标:65(9) 页码:2366-70
专利号:US-8673371-B2 优先权日:2010-12-17 标题:Composition for treating vitiligo or canities comprising extract from sophora japonica as active ingredient 发明人:KIM YOUNG CHUL; KANG CHUL HO; PARK EUN YE; KIM SANG NAM 权利人:KIM YOUNG CHUL; KANG CHUL HO; PARK EUN YE; KIM SANG NAM; KEIMYUNG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION 摘要:Disclosed is a composition for treating or preventing vitiligo or canities comprising Sophora japonica extract as an active ingredient. The Sophora japonica extract enhances melanin synthesis by increasing the activity of tyrosinase which is critical in intracellular melanin synthesis and promoting the expression of tyrosinase and TRP-2 mRNA. Furthermore, since the Sophora japonica extract is a natural substance with little cytotoxicity, it may be developed into a therapeutic agent for vitiligo and canities caused by depigmentation in skin and hair.
专利号:CN-109694377-A 优先权日:2019-03-08 标 题:Synthesis method of Pulsatilla
[参考文献]: Jiang L, Et Al. Anti-Inflammatory Effects Of Anemonin On Acute Ulcerative Colitis Via Targeted Regulation Of Protein Kinase C-θ. Chin Med. 2022 Mar 28;17(1):39. [参考文献]: Lee Th, Et Al. Anemonin, From Clematis Crassifolia, Potent And Selective Inducible Nitric Oxide Synthase Inhibitor. J Ethnopharmacol. 2008 Mar 28;116(3):518-27.
合成参考文献
参考文献:10.1007/bf02980120 摘要:Bang SC, Kim Y, Yun MY, Ahn BZ. 5-Arylidene-2(5H)-furanone derivatives: synthesis and structure-activity relationship for cytotoxicity. Arch Pharm Res. 2004 May;27(5):485–94. doi: 10.1007/bf02980120.