CAS: 83-26-1; Pindone

上下游产品

3,3-dimethyl-butan-2-one phthalic acid dimethyl ester 28H32O8C28H32O8 13H15IO2C13H15IO2pyrazol-4(1H)-one3-(1,1-dimethylethyl)indeno1,2-cpyrazol-4(1H)-one pyrazol-4-one1-carbamoyl-3-tert-butyl-3a,8b-dihydro-8b-hydroxyindeno1,2-cpyrazol-4-one 3-tert-Butyl-1-phenyl-1H-indeno[1,2-c]pyrazol-4-one isoxazol-4-one3-t-Butylindeno1,2-cisoxazol-4-one

📜2,13-Ditert-Butyl-3,14-Dioxapentacyclo[13.7.0.04,12.05,10.016,21]Docosa-1(22),5,7,9,11,16,18,20-octaene-2,4,11,13,15,22-Hexol置于盐酸体系中,用 乙醇 作为反应溶剂,化学反应 0.08H,反应生成 鼠完
参考文献:Lemke,Thomas L.; Sawhney,Kailash N.; Lemke,B. Kaye,Journal Of Heterocyclic Chemistry,1982,Vol. 19,P. 363-368
标题:Lemke,Thomas L.; Sawhney,Kailash N.; Lemke,B. Kaye,Journal Of Heterocyclic Chemistry,1982,Vol. 19,P. 363-368

专利信息

专利号:US-8293930-B1
优先权日:2004-06-25
标题 :One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:NAIDU RAGINA; CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.

专利号:US-7893283-B2
优先权日:2004-06-04
标题:Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates.

专利号:EP-0443532-B1
优先权日:1990-02-20
标题:Temporary minimal protection synthesis of LH-RH analogs
发明人：NESTOR JOHN J JR; MCCLURE NATALIE L
权利人:SYNTEX INC
摘要:A solid phase synthesis of LH-RH analogs in which the amino acids serine and histidine, if present, are side chain protected during the synthesis with groups labile to selected alpha -amino or deprotecting agents.

专利号:WO-2008032104-A1
优先权日:2006-09-15
标题:One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：WALKER ROSS THOMSON; NAIDU RAGINA
权利人:CHATHAM BIOTEC LTD; WALKER ROSS THOMSON; NAIDU RAGINA
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction, of protecting the C-10 and attaching a side chain at C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and intermediates used therein.

专利号:US-7838694-B2
优先权日:2004-04-23
标题 :Semi-synthesis and isolation of taxane intermediates from a mixture of taxanes
发明人：NAIDU RAGINA; FOO SAMUEL SIANG KIANG
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis and isolation of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis and isolation of 10-deacetylbaccatin III, the semi-synthesis of a mixture of 10-deacetylbaccatin III and baccatin III, and protected derivatives thereof, from a mixture of taxanes.

专利号:US-7906661-B2
优先权日:2004-06-29
标 题 :Semi-synthetic conversion of paclitaxel to docetaxel
发明人：NAIDU RAGINA; FOO SAMUEL SIANG KIANG; XUE BAOYU; FAN BO
权利人:CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane derivatives useful in the preparation of docetaxel, in particular, the semi-synthesis of protected taxane derivatives in a one pot reaction of protecting the C-2′, C-7 and C-10 positions and introducing a t-Boc group at the nitrogen of the amide group at the C-3′ position in paclitaxel and subsequently conversion to docetaxel, and derivatives used therein.