CAS: 6627-89-0; Tert-Butyl Phenyl Carbonate

该化合物是一种有机化合物,其特征是其酯类功能组,其成分是乙丁基酒精和苯基碳酸酯,其成分一般是淡黄色液体的无色,在标准条件下以其相对低的挥发性和稳定性而闻名,在乙醚和丙酮等有机溶剂中溶解,但水溶解度有限. 丁基苯碳酸酯经常被用作有机合成的试剂,特别是在保护各种化学反应中的氢氧基组方面,其稳定性使其适合于聚合化学应用,并成为制药和农用化学品生产的中间体.此外,它表现出良好的热稳定性,在高温应用中具有优势.然而,与许多有机化合物一样,它应该受到谨慎处理,因为如果吸入或摄取,它可能会对健康造成危害,因此在使用过程中必须采取适当的安全措施.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号24424-99-5 二碳酸二叔丁酯 | CAS号108-95-2 苯酚 | CAS号404586-94-3 B°C-1-叔丁氧基-1,2-二氢异喹啉 | CAS号1885-14-9 氯甲酸苯酯 | CAS号75-65-0 叔丁醇 | CAS号865-47-4 叔丁醇钾 | CAS号88345-85-1 phenyl 5-bromo-... | CAS号90731-83-2 phenyl 3-bromop... | CAS号60142-89-4 7-(B°C-氨基)庚酸 | CAS号51644-96-3 N-(5-氨基戊基)氨基甲酸叔丁酯 | CAS号142348-04-7 tert-butyl N-(3... | CAS号149632-73-5 2-N-B°C-1,2-丙二胺 | CAS号255735-88-7 (2-氨基丙基)氨基甲酸叔丁酯 | CAS号92-53-5 4-苯基吗啉 | CAS号480424-71-3 碳酸叔丁基-2-(4,4,5,... | CAS号5176-27-2 N-B°C-吡咯 | CAS号132128-00-8 B°Cdien*HCl | CAS号193206-49-4 N1-B°C-2,2′-亚氨基二乙胺

合成工艺路线路线简述

    📜氯甲酸苯酯 以 四氢呋喃 作为反应溶剂,化学反应 2.5H,反应生成 叔丁基苯基碳酸酯
    参考文献:Comins,Daniel L.; Mantlo,Nathan B.,Journal Of Heterocyclic Chemistry,1983,Vol. 20,P. 1239-1243
    标题:Comins,Daniel L.; Mantlo,Nathan B.,Journal Of Heterocyclic Chemistry,1983,Vol. 20,P. 1239-1243

    海关参考信息

    专利信息


    专利号:US-10597340-B2
    优先权日:2013-05-10
    标 题:Synthesis of fluorinated radiopharmaceuticals via electrochemical fluorination
    发明人:SADEGHI SAMAN; HE QINGGANG; LEBEDEV ARTEM
    权利人:UNIV CALIFORNIA
    摘要:Provided herein are methods and compositions for the electrochemical selective radiofluorination of aromatic molecules. The resulting fluorine-18 labeled compounds are ideal radionuclides for use in Positron Emission Tomography (PET); they are also difficult to radiolabel efficiently and with high specific activity using existing approaches. For example, radiopharmaceuticals such as [F18]L-DOPA, which is indispensable in PET brain disease imaging, may be made electrochemically with high radiochemical yield and high specific activity using 18F-. The invention process described herein opens new possibilities and provides wider access to PET tracers such as 18F-L-Dopa, since 18F- is much more widely available than the 18F 2 , currently used for synthesis of electron rich substrates.

    专利号:US-6410643-B1
    优先权日:2000-03-09
    标题 :Solid phase synthesis method and reagent
    发明人:SWANSON MELVIN J
    权利人:SURMODICS INC
    摘要:A reagent composition adapted to be coated onto a support surface in order to provide that surface with a high density of reactive groups. The surface, thus coated, can be used for any suitable purpose, and is particularly well suited for use as a solid phase synthesis support surface. The synthesis support surface, in turn, can be used in repetitive and combinatorial syntheses such as the synthesis of polynucleotides, polypeptides and polysaccharides. The polymeric coating can be used to provide increased effective surface area, particularly in situations in which the effective area of the support surface is itself limited, as on the surface of a silicon wafer. In so doing, the polymeric coating provides an optimal combination of such properties as reactive density and surface area or volume.

    专利号:US-12122769-B2
    优先权日:2017-10-19
    标题 :Synthesis of antibacterial aminoglycoside analogs
    发明人:TREND RAISSA; DAPPEN MICHAEL; HENRY CHRISTOPHER E; GOLDBLUM ADAM AARON; AGGEN JAMES BRADLEY; MENDONÇA RICARDO FILIPE DE JESUS GONÇALVES; SARDINHA JOÃO CARLOS FALCÃO
    权利人:CIPLA USA INC
    摘要:The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.

    专利号:AU-2022253019-A1
    优先权日:2021-04-09
    标题:Synthesis of rapamycin analog compounds

    专利号:EP-3697797-A1
    优先权日:2017-10-19
    标题 :Synthesis of antibacterial aminoglycoside analogs

    专利号:CN-111655709-A
    优先权日:2017-10-19
    标 题:Synthesis of Antibacterial Aminoglycoside Analogs

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Jesper Stergaard, Et Al. Determination Of Octanol-Water Partition Coefficients For Carbonate Esters And Other Small Organic Molecules By Microemulsion Electrokinetic Chromatography. Electrophoresis. 2003 Mar;24(6):1038-46.

    合成参考文献


    摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 161.
    摘要:Ros, A.; Fernández, R.; Lassaletta, J. M., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 417.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知