专利号:WO-2016111658-A1 优先权日:2015-01-07 标 题:Synthesis of thiosemicarbazone derivatives comprising sulphonamide group with potential anticonvulsant activity 发明人:IYIDOGAN AYSEGUL; EMRE EMINE ELCIN; TOPALFAKIOGÄžLU RAHIME BETÜL; KAYMAKÇIOÄžLU BEDIA; ARICIOÄžLU FEYZA 权利人:IYIDOGAN AYSEGUL; EMRE EMINE ELCIN 摘要:The present invention relates to the synthesis method of thiosemicarbazone derivatives comprising sulphonamide group and having high anticonvulsant/antiepileptic activity.
专利号:US-10975048-B2 优先权日:2015-12-14 标题 :Composition of 1,3,4-selenadiazole containing compounds with pharmacological activity 发明人:RUAN BENFANG HELEN; RUAN JENNIFER JIN 权利人:HANGZHOU JENNIFER BIOTECH CO LTD 摘要:The invention belongs to the field of biomedical research involving the 1,3,4-selenyldiazo derivatives that have cell protective activity. Because there are not so many heterocyclic selenium compounds, we synthesized a new type of selenium analog of BPTES. As the isoacceptor of BPTES, the compounds have antitumor activity, anti-oxidation and cell protection function. Currently many drugs contain the thiodiazo motif, so synthesis of selenyldiazo functional group could further optimize these drugs and are important in new drug development and application.
专利号:CN-112250661-A 优先权日:2020-11-18 标题 :A kind of method for catalyzing synthesis of lactide
专利号:US-7045503-B1 优先权日:1996-07-12 标 题 :Radiometal-binding peptide analogues 发明人:MCBRIDE WILLIAM J; GRIFFITHS GARY L 权利人:IMMUNOMEDICS INC 摘要:Novel metal binding ligands are disclosed that may be coupled to peptides for use in methods of diagnosis and therapy. Peptides containing the ligands are produced using a method wherein ligand introduction or cyclization can be conducted at any point during the synthesis of the peptide. Such peptide derivatives are readily labeled with radiometals, such as isotopes of rhenium or technetium, while retaining their ability to tightly bind specific peptide receptors.
专利号:CN-112250661-B 优先权日:2020-11-18 标题:A kind of method for catalyzing synthesis of lactide
专利号:US-2006211603-A1 优先权日:2004-08-18 标 题:Ramoplanin derivatives possessing antibacterial activity 发明人:RAJU BORE G; CIABATTI ROMEO; MAFFIOLI SONIA I; SINGH UPINDER; ROMANO GABRIELLA; MICHELUCCI ELENA; TISENI PAOLO S; CANDIANI GIANPAOLO; KIM BUM; O'DOWD HARDWIN 权利人:VICURON PHARM INC 摘要:Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
[参考文献]: Derya Kara, Et Al. Determination Of Trace Heavy Metals In Soil And Sediments By Atomic Spectrometry Following Preconcentration With Schiff Bases On Amberlite Xad-4. J Hazard Mater. 2009 Jun 15;165(1-3):1165-9.
合成参考文献
参考文献:10.1107/s1600536811008920 摘要:Dzulkifli NN, Farina Y, Yamin BM, Baba I, Tiekink ER. 3-[(E)-(4-Chloro-benzyl-idene)amino]-1-phenyl-thio-urea. Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 01;67(Pt 4):o872.