CAS: 442-52-4; Clemizole

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CAS号123-75-1 四氢吡咯 | CAS号7189-18-6 1-(4-Chlorobenz... | CAS号622-95-7 4-氯溴苄 | CAS号2948-92-7 2-(pyrrolidin-1... | CAS号4857-04-9 2-氯甲基苯并咪唑 | CAS号718634-79-8 pyrrolidino-ace... | CAS号5822-16-2 N-(p-Chlorobenz... | CAS号5729-18-0 N-(Chlorobenzyl... | CAS号109037-60-7 pyrrolidino-ace... | CAS号104-86-9 4-氯苄胺

📜2-(甲基硫代)苯并咪唑置于hexaammonium Heptamolybdate Tetrahydrate,Eosin Y,双氧水,Sodium Hydride体系中,用 甲醇,乙醇,水,N,N-二甲基甲酰胺,乙腈,Mineral Oil 作为反应溶剂,化学反应 46.0H,反应生成 吡咯咪唑
参考文献:曙红y促进芳香砜的无金属氨基甲基化
标题:曙红y促进芳香砜的无金属氨基甲基化
摘要:报道了杂环与有机染料的光催化氨甲基化.通过氨基甲基自由基形成的 C-C 键可以一步获得一系列功能化的杂环,而无需过渡金属.
DOI:10.1002/chem.202102124

专利信息

专利号:WO-2025019775-A1
优先权日:2023-07-19
标题 :Endoxifen compositions and methods of use thereof and synthesis thereof
发明人：QUAY STEVEN
权利人:ATOSSA THERAPEUTICS INC
摘要:Described herein are endoxifen compositions comprising novel compounds and methods of use thereof. Methods of synthesis for the compositions are described herein. The endoxifen compositions described herein may exhibit aromatase inhibition activity or estrogen receptor activity. The endoxifen compositions described herein may be useful in the treatment of a condition in a subject, such as cancer.

专利号:US-2025241876-A1
优先权日:2023-07-19
标 题:Anti-tumor compounds and methods of use thereof and synthesis thereof
发明人：QUAY STEVEN CARL
权利人:ATOSSA THERAPEUTICS INC
摘要:Described herein are pharmaceutical compounds and compositions and methods of making thereof. Methods of synthesis for the compounds are described herein. The compounds or compositions described herein may exhibit aromatase inhibition activity or estrogen receptor activity. The compounds and compositions described herein may be useful in the treatment of a condition in a subject.

专利号:US-5922335-A
优先权日:1995-05-15
标 题:Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
发明人：PTCHELINTSEV DMITRI
权利人:AVON PROD INC
摘要:Novel uses of 3'-(L-ascorbyl-2-o-phosphoryl)-cholesterol, 3'-(L-ascorbyl-3-o-phosphoryl)-cholesterol, structural or functional isomers thereof and salts thereof (referred to collectively as 'APC compounds') are disclosed. Such novel uses include a method of reducing epidermal synthesis of abnormal elastin, especially epidermal synthesis of abnormal elastin that results from exposure to UV radiation. Also disclosed is a novel method of stimulating keratinocyte formation of triglycerides. In addition, a novel method of achieving antioxidant activity, both in the skin and also in topical compositions, is disclosed.

专利号:WO-2018035281-A1
优先权日:2016-08-17
标 题:Northern-southern route to synthesis of bacteriochlorins

专利号:EP-3104712-A1
优先权日:2014-02-12
标题 :Improved process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones

专利号:WO-2016044243-A1
优先权日:2014-09-16
标题 :Pyrimidine nucleoside phosphoramidate
发明人：PHADKE AVINASH; HASHIMOTO AKIHIRO; ELY RICHARD JAMES
权利人:ACHILLION PHARMACEUTICALS INC
摘要:The disclosure describes methods of synthesis of phosphoramidate ester derivatives. Also disclosed are morphic forms of (S) -isopropyl 2- (((S)-(((2R,3R,4R,5R) -5-(5-deutero-2,4- dioxo-3,4-dihydropyrimidin- 1( 2H )-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2- yl)dideuteromethoxy)-(phenoxy)phosphoryl)amino)propanoate and antiviral therapy using (S) - isopropyl 2- (((S)-(((2R,3R,4R,5R) -5-(5-deutero-2,4-dioxo-3,4-dihydropyrimidin-1( 2H )-yl)-3,4- dihydroxy-4-methyltetrahydrofuran-2-yl)dideuteromethoxy)(phenoxy)phosphoryl)amino)- propanoate (e.g., anti-HCV therapies).