CAS: 431-47-0; Methyl Trifluoroacetate

上下游产品

CAS号34557-54-5 methane | CAS号407-25-0 三氟乙酸酐(TFAH) | CAS号76-05-1 三氟乙酸(TFA) | CAS号67-56-1 甲醇 | CAS号31181-64-3 2-甲基-5-溴吡啶 N-氧化物 | CAS号82817-12-7 [(1-chloro-2,2,... | CAS号75-11-6 二碘甲烷 | CAS号358-23-6 三氟甲磺酸酐 | CAS号124-38-9 二氧化碳 | CAS号74-98-6 丙烷 | CAS号109872-87-9 methyl 2,2-difl... | CAS号75-89-8 三氟乙醇 | CAS号431-46-9 三氟乙醛甲基半缩醛 | CAS号507-52-8 2-三氟甲基-2-丙醇 | CAS号387-89-3 2-(三氟乙酰基)环己酮 | CAS号50632-83-2 4-[(三氟乙酰基)氨基]丁酸 | CAS号383-70-0 L-三氟乙酰甘氨酸 | CAS号56915-87-8 N-(3-乙酰基苯基)-2,2... | CAS号58808-59-6 4-(三氟乙酰基)苯甲酸 | CAS号379-18-0 Α-(三氟甲基)二苯甲醇

在 六甲基二硅氧烷体系中,用 氘代乙腈 作为反应溶剂,90.0 °C,308.18 Kpa 条件下,反应 48.0H,以59%的收率获得产物三氟乙酸甲酯
参考文献:Rh Iii-Me 键的功能化:使用"封端芳烃"配体促进 Me-X 还原消除
标题:Rh Iii-Me 键的功能化:使用"封端芳烃"配体促进 Me-X 还原消除
摘要:我们展示了如何通过使用"封端芳烃"配体将来自 Ch 4活化催化剂的 Mex 产率从 12% 提高到 90%.四个 (Fp)Rh Iii (Me)(Tfa) 2 {fp ="封端芳烃"配体,包括 8,8'-(1,2-亚苯基)二喹啉 (6-Fp),8,8'-(1,2-萘)二喹啉 (6-Np Fp),1,2-双(N-7-氮杂吲哚基)苯 (5-Fp) 和 1,2-双(N-7-氮杂吲哚基)萘 (5-Np Fp))} 复合体.这些配合物和 (Dpe)Rh Iii (Me)(Tfa) 2(Dpe = 1,2-Di-2-Pyridylethane) 被合成并测试它们在 Mex(x = Tfa 或卤化物)的还原消除方面的性能.使用 Fp 配体的目的是阻断配位位点,使 Rh Iii复合物不稳定并促进 Mex 还原消除.基于单晶 X 射线衍射研究,6-Fp 和 6-Np Fp 连接的 Rh 配合物的
DOI:10.1021/acs.Organomet.1C00223

专利信息

专利号:US-6252105-B1
优先权日:1998-07-06
标题:Synthesis of low-fluoride organic compounds
发明人：BRAUN MAX; EICHER JOHANNES; JANSSENS FRANCINE; EICHHOLZ KERSTIN; PALSHERM STEFAN
权利人:SOLVAY FLUOR & DERIVATE
摘要:Organic compounds, e.g. fluorinated organic compounds such as fluorinated carboxylic acids or fluorinated carboxylic acid chlorides, may contain small amounts of carboxylic acid fluorides, hydrogen fluoride or hydrolyzable fluoride, which during the preparation of derivatives of the fluorinated organic compounds, for example by esterification, may yield corrosive fluorides or hydrogen fluoride. The invention is a method for the synthesis and/or purification of preferably fluorinated organic compounds such as carboxylic acids, carboxylic acid chlorides and derivatives such as esters thereof, starting from corresponding carboxylic acid chlorides containing acid fluorides or hydrolyzable fluoride, and alcohols under the catalytic action of 'onium' salts of carboxylic acids, to obtain products which have a low fluoride content. Alternatively, an inorganic oxide adsorbent is utilized. The method is especially suitable for the synthesis of esters of trifluoroacetic acid, chlorodifluoroacetic acid, trifluoroacetoacetic acid and/or difluoroacetoacetic acid.

专利号:US-7619116-B2
优先权日:2003-12-17
标 题:Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation
发明人：DAMBRIN VALERY; LENOIR JEAN-YVES; SCHNEIDER JEAN-MARIE; GUILLAMOT GERARD; FOLLET MICHEL; BECKER ABRAM
权利人:PRODUCTS CHIMIQUES AUXILIAIRES
摘要:A subject matter of the present invention is novel intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts, and also the associated preparation process.

专利号:US-11370736-B2
优先权日:2019-04-01
标 题:Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation
发明人：DUB PAVEL A; BATRICE RAMI J; GORDON JOHN C
权利人:TRIAD NAT SECURITY LLC
摘要:This application is directed to use of transition metal-ligand complexes to hydrogenate fluorinated esters and carboxamides into fluorinated hemiacetals. Methods for synthesis of certain ligands are also provided.

专利号:US-11306157-B2
优先权日:2018-12-21
标 题:Expedient synthesis of core disaccharide building blocks from natural polysaccharides for heparan sulfate oligosaccharide assembly
发明人：HSIEH-WILSON LINDA C; PAWAR NITIN J; WANG LEI
权利人:CALIFORNIA INST OF TECHN
摘要:Methods for the preparation of oligosaccharide products from polysaccharide starting materials are disclosed. The methods include: hydrolyzing a glucosamine-containing polysaccharide starting material, such as heparin or heparosan, under conditions sufficient to form an oligosaccharide intermediate (e.g., a GlcN-IdoA disaccharide intermediate or a GlcA-GlcN disaccharide intermediate), and converting the oligosaccharide intermediate to the oligosaccharide product. Conversion of the oligosaccharide intermediates to the oligosaccharide products may include one or more esterification, acylation, epimerization, protection, and deprotection steps. Preparation of higher-order oligomers is described, as well as methods for selective oligosaccharide sulfation.

专利号:US-2024209018-A1
优先权日:2021-03-22
标题:Universal linker reagents for dna synthesis
发明人：REED MICHAEL W; WU CHENG-HSIEN; COOPER JOHN; DEMPCY ROBERT O
权利人:GENSCRIPT USA INC; CUSTOMARRAY INC
摘要:Provided herein are methods and compositions for oligonucleotide synthesis utilizing universal linker phosphoramidites. Methods and reagents are described with DNA synthesis using controlled pore glass (CPG) solid supports, and on platinum coated electrodes for electrochemical DNA synthesis. The universal linkers can be used as spacers in single-column PCR primer synthesis to generate 2 strands with free 3′-hydroxy termini after cleavage. The methods and compositions utilize a solid support system for synthesis of oligonucleotides, wherein the support has platinum electrodes and a universal linker, optionally wherein the platinum electrode is coated with an amine. The methods and compositions further describe use of universal linker phosphoramidites and the platinum electrode is coated with a monosaccharide, or a disaccharide.

专利号:US-2009234121-A1
优先权日:2008-01-16
标 题 :Tridentate (nnc) catalysts for the selective oxidation of hydrocarbons
发明人：PERIANA ROY A; GODDARD III WILLIAM A; OXGAARD JONAS; YOUNG KENNETH
权利人:PERIANA ROY A; GODDARD III WILLIAM A; OXGAARD JONAS; YOUNG KENNETH
摘要:The synthesis of discrete, air, protic, and thermally stable transition metal NNC complexes that catalyze the CH activation and functionalization of alkanes and arenes is disclosed. Methods for the selective conversion of methane to methanol or methyl esters in acidic and neutral media are disclosed.