📜2-甲基庚烷-1-醛置于盐酸,氢碘酸,锌体系中,化学反应生成4-甲基-癸烷 参考文献:Hydrogenation Of Vitamin B1 And Other Quaternary Thiazoles1 标题:Hydrogenation Of Vitamin B1 And Other Quaternary Thiazoles1 摘要: Doi:10.1021/ja01278A005
专利号:US-9988349-B2 优先权日:2014-01-03 标 题:Direct stereospecific synthesis of unprotected aziridines from olefins 发明人:ESS DANIEL HALSELL; FALCK JOHN RUSSELL; JAT JAWAHAR LAL; KURTI LASZLO 权利人:ESS DANIEL HALSELL; FALCK JOHN RUSSELL; JAT JAWAHAR LAL; KURTI LASZLO 摘要:A method for the direct stereospecific conversion of structurally diverse mono-, di-, tri- and tetra-substituted olefins to N—H, N-alkyl, N-cycloalkyl, or N-aralkyl aziridines using a hydroxylamine amination agent with transition metal catalyst. The method is operationally simple (i.e., one-pot), scalable and fast at ambient temperature.
专利号:US-2004053999-A1 优先权日:1997-09-17 标题 :Novel compounds and methods for synthesis and therapy 发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A 摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-9963685-B2 优先权日:2013-02-28 标题 :Engineered transaminase polypeptides for industrial biocatalysis 发明人:QUINTANAR-AUDELO MARTINA; EBERHARD ELLEN; NAZOR JOVANA; SMITH DEREK; WANG CUIXIA 权利人:CODEXIS INC 摘要:The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
专利号:US-6225341-B1 优先权日:1995-02-27 标 题:Compounds and methods for synthesis and therapy 发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A 权利人:GILEAD SCIENCES INC 摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-2017191043-A1 优先权日:2011-09-08 标题 :Biocatalysts and methods for the synthesis of substituted lactams
专利号:US-2023313155-A1 优先权日:2011-09-08 标题 :Biocatalysts and methods for the synthesis of substituted lactams
参考文献:10.1007/s12010-015-1898-2 摘要:Hinge V, Patil H, Nadaf A. Comparative Characterization of Aroma Volatiles and Related Gene Expression Analysis at Vegetative and Mature Stages in Basmati and Non-Basmati Rice (Oryza sativa L.) Cultivars. Applied Biochemistry and Biotechnology. 2015 Oct 19;178(4):619–39. doi: 10.1007/s12010-015-1898-2. 参考文献:10.1007/b94830