CAS: 267006-26-8; Potassium (3,5-Difluorophenyl)Trifluoroborate
该化合物是一种有机有机体化合物,通常用作交叉相交反应,特别是铃木-米亚乌拉相交反应的多用途试剂,其主要优点包括:与黄酸相比稳定性增强,减少蛋白质侧反应,改善环境条件下的处理;苯环上的电排二氟替代成分进一步稳定了黄碱,便利了与卤化物的有效结合;该化合物在极地有机溶剂中表现出良好的溶解性,确保与广泛的反应条件兼容性;其晶体固态形式可以进行精确的称重和长期储存,从而成为合成药物,农用化学品和材料科学方面的可靠选择.
MSDS等安全信息
合成工艺路线路线简述
📜3,5-Difluorophenylmagnesium Bromide置于硼酸三甲酯,盐酸,二氟化氢钾体系中,用 乙醚,甲醇,水 用作溶剂,以58%的收率获得(3,5-二氟苯基)三氟硼酸钾
参考文献:(Fluoroorgano)Fluoroboranes And-Fluoroborates I: Synthesis And Spectroscopic Characterization Of Potassium Fluoroaryltrifluoroborates And Fluoroaryldifluoroboranes
标题:(Fluoroorgano)Fluoroboranes And-Fluoroborates I: Synthesis And Spectroscopic Characterization Of Potassium Fluoroaryltrifluoroborates And Fluoroaryldifluoroboranes
摘要:A Convenient Preparation Of K[arbf3] (Ar= 2-C6H4F,3-C6H4F,4-C6H4F,2,6-C6H3F2,3,5-C6H3F2,2,4,6-C6H2F3,3,4,5-C6H2F3,2,3,4,5-C6Hf4 And C6F5) Is Offered And The Ir And Multinuclear NMR Spectra Of These Salts Are Reported. Treatment Of The Trifluoroborate Salts With Bf3 In Chlorocarbon Solvents Provides An Easy Synthetic Route To The Corresponding Aryldifluoroboranes Arbf2. The Multinuclear NMR Spectra Of Arbf2 Are Presented. The Electron Substituent Effect Of The [-Bf3](-)-Group Shows This Substituent As One Of The Strongest Sigma-Electron Donors,While Its Pi-Electron Influence Is Negligible (Sigma(I) =-0.32,Sigma(R) =-0.07). (C) 2000 Elsevier Science S.A. All Rights Reserved.
Doi:10.1016/s0022-328X(99)00690-7
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Molander, G. A.; Beaumard, F., Science of Synthesis Knowledge Updates, (2013) 3, 108.
📝 需求与反馈
尽可能描述清楚需求与问题信息
