CAS: 261165-05-3; (1S,3R)-3-((Tert-Butoxycarbonyl)Amino)Cyclopentanecarboxylic Acid

相似化合物

489446-85-7 161601-29-2 855863-93-3

上下游产品

CAS号151907-80-1 (1R,4S)-4-((叔丁氧... | CAS号554451-12-6 (1S,3R)-Methyl ... | CAS号693245-53-3 (1R,4S)-tert-bu... | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号71830-07-4 (1S,3R)-3-氨基环戊羧酸 | CAS号49805-30-3 氮杂双环 | CAS号24647-29-8 2-氮杂双环[2,2,1]庚-3-酮 | CAS号21472-89-9 1-氮杂双环[2.2.1]-3-庚酮 | CAS号774212-81-6 (1R,3S)-1-(B°C-... | CAS号554451-12-6 (1S,3R)-Methyl ...

(1R,4S)-N-Boc-4-氨基环戊-2-烯甲酸置于5%-Palladium/activated Carbon 氢气体系中,用 甲醇 用作溶剂,20.0 °C,275.8 Kpa 条件下,反应 2.0H,反应生成(1S,3R)-(+)-3-(Boc-氨基)环戊烷羧酸
参考文献: Novel Dipeptidyl Peptidase Iv Inhibitors; Process For Their Preparation And Compositions Containing Them[fr] Nouveaux Inhibiteurs De La Dipeptidyl Peptidase Iv,Procede De Preparation De Ces Inhibiteurs Et Compositions Contenant Ces Inhibiteurs
标题: Novel Dipeptidyl Peptidase Iv Inhibitors; Process For Their Preparation And Compositions Containing Them[fr] Nouveaux Inhibiteurs De La Dipeptidyl Peptidase Iv,Procede De Preparation De Ces Inhibiteurs Et Compositions Contenant Ces Inhibiteurs
摘要:该发明涉及新型有机化合物,更特别地,一般式(i)的新型二肽基肽酶iv(dpp-Iv)抑制剂,其中:Y为-S(O)M-,-Ch2-,-Chf-或-Cf2;X和z独立地为-C(=o)-,-Nr3-,-O-或-S(O)M-;M的每次出现独立地为0,1或2;A为0,1或2;B为0,1或2;在碳环中的虚线[----]表示一个可选的双键;R1为取代或未取代的烷基,取代或未取代的烯基,取代或未取代的炔基,取代或未取代的环烷基,取代或未取代的环烷基烷基,取代或未取代的环烯基,取代或未取代的芳基,取代或未取代的芳基烷基,取代或未取代的杂芳基,取代或未取代的杂环烷基,或取代或未取代的杂芳基烷基;R2为氢,腈(-Cn),Cooh,或羧基的同分异构体;或其类似物,互变异构体,对映异构体,非对映异构体,位置异构体,立体异构体,多晶型,药学上可接受的盐,N-氧化物,药学上可接受的溶剂化合物和含有它们的药物组合物.

专利信息

专利号:US-2023295613-A1
优先权日:2020-02-14
标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming
发明人：JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J
权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

专利号:US-11814621-B2
优先权日:2018-06-01
标题 :Expanding the chemical substrates for genetic code reprogramming
发明人：JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; MOORE JEFFREY S; SCHWIETER KENNETH E; SCHWARZ KEVIN JEROME
权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.