CAS: 2597-03-7; Phenthoate

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欧盟法规

统一分类与标签ECHA物质ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

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4-anilinophenol

合成工艺路线路线简述

    对羟基二苯胺置于三氯化铁 苯胺体系中,化学反应生成稻丰散
    参考文献:Para-Aminophenol Derivatives
    标题:Para-Aminophenol Derivatives
    摘要:一种从粗对氨基苯酚溶液中制备二芳基对苯二胺的工艺,例如通过在水酸性反应介质中催化加氢硝基苯获得的溶液.该工艺包括将含有对氨基苯酚的酸性溶液与苯胺,混合甲基苯胺,邻甲苯胺,混合二甲苯胺和它们的混合物等芳香胺中选择的一种接触,在芳香胺从粗料溶液中提取对氨基苯酚并与其分离的条件下.然后,含有芳香胺萃取剂,对氨基苯酚和少量杂质的分离溶液与烷基化催化剂接触,以产生二芳基对苯二胺.

    海关参考信息

    专利信息


    专利号:US-2023313255-A1
    优先权日:2020-07-15
    标题:Massively Parallel Enzymatic Synthesis of Polynucleotides
    发明人:HORGAN ADRIAN; LACHAIZE HENRI; VERARDO DOMIANO; GODRON XAVIER
    权利人:DNA SCRIPT
    摘要:The invention is directed to methods and compositions for inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions of the invention include formulations of synthesis reagents for inkjet delivery including, but not limited to, TdT coupling reaction buffers and 3′-O-protected dNTP monomers.

    专利号:US-2011195450-A1
    优先权日:2005-09-27
    标 题 :In Vitro Protein Synthesis Systems for Membrane Proteins that Include Adolipoproteins and Phospholipid Adolipoprotein Particles
    发明人:KUDLICKI WIESLAW; FLETCHER JULIA; KATZEN FEDERICO
    权利人:LIFE TECHNOLOGIES CORP
    摘要:In vitro protein synthesis systems and methods are provided that produce membrane proteins in soluble form. In some aspects, the invention provides methods of synthesizing proteins using in vitro protein synthesis systems that include an apolipoprotein, in which higher yields of soluble protein are produced than in the absence of the apolipoprotein. Apolipoproteins useful in the present invention include naturally occurring apolipoproteins, as well as sequence variants of wild-type apolipoproteins, and engineered apolipoproteins. The apolipoproteins can be provided in an in vitro protein synthesis system associated with lipid or not associated with lipid. The invention also provides compositions and kits for synthesis of proteins in soluble form, in which the compositions and kits include cell extracts for protein translation and at least one apolipoprotein biomolecule.

    专利号:WO-2007038755-A1
    优先权日:2005-09-27
    标 题:In vitro protein synthesis systems for membrane proteins that include apolipoproteins and phospholipid-apolipoprotein particles
    发明人:KUDLICKI WIESLAW; FLETCHER JULIA; KATZEN FEDERICO
    权利人:INVITROGEN CORP; KUDLICKI WIESLAW; FLETCHER JULIA; KATZEN FEDERICO
    摘要:In vitro protein synthesis systems and methods are provided that produce membrane proteins in soluble form. In some aspects, the invention provides methods of synthesizing proteins using in vitro protein synthesis systems that include an apolipoprotein, in which higher yields of soluble protein are produced than in the absence of the apolipoprotein. Apolipoproteins useful in the present invention include naturally occurring apolipoproteins, as well as sequence variants of wild-type apolipoproteins, and engineered apolipoproteins. The apolipoproteins can be provided in an in vitro protein synthesis system associated with lipid or not associated with lipid. The invention also provides compositions and kits for synthesis of proteins in soluble form, in which the compositions and kits include cell extracts for protein translation and at least one apolipoprotein biomolecule.

    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:WO-2024141628-A1
    优先权日:2022-12-31
    标 题:Variable viscosity inks for inkjet delivery of enzyme reagents
    发明人:HORGAN ADRIAN; VERARDO DAMIANO; ADELIZZI BEATRICE
    权利人:DNA SCRIPT
    摘要:The invention is directed to formulations of terminal deoxynucleotidyl transferases (TdTs) inks employing variable viscosity modifiers and their use in inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate.

    专利号:US-2010233782-A1
    优先权日:2005-09-27
    标 题:Isolated phospholipid-protein particles
    发明人:KATZEN FEDERICO; FLETCHER JULIA; KUDLICKI WIESLAW; BEECHEM JOSEPH; WANG LILIN
    权利人:LIFE TECHNOLOGIES CORP
    摘要:Systems and methods are provided for producing a protein of interest that is typically not amenable to expression in soluble form in in vitro expression systems. In some aspects, the invention provides methods of synthesizing proteins using in vitro protein synthesis systems that include a scaffold protein such as apolipoprotein or an amphipathic alpha helix containing (“AAHCâ€?) protein, in which higher yields of soluble protein are produced than in the absence of the scaffold protein. The scaffold proteins may be provided in an in vitro protein synthesis system associated with lipid or not associated with lipid. The scaffold protein may be provided as a protein per se or may be encoded by a nucleic acid template and co-expressed with the protein of interest. The invention also provides compositions and kits for synthesis of proteins in soluble form, in which the compositions and kits include cell extracts for protein expression and isolation.
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    主要参考文献


    1: Li ZY, Zhang ZC, Zhang L, Leng L. Enantioselective degradation and chiral stability of phenthoate in soil. Bull Environ Contam Toxicol. 2007 Aug;79(2):153-7. Epub 2007 May 18. Japanese.

    合成参考文献


    摘要:World Review of Pest Control., 9(119), 1970
    摘要:Toxicology and Applied Pharmacology., 6(147), 1964
    摘要:Chemistry of Pesticides, Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971, -(374), 1971
    摘要:Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -(56), 1982
    摘要:Special Publication of the Entomological Society of America., 78-1(40), 1978
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