CAS: 25229-42-9; Cicrotoic Acid

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Ethyl 3-Cyclohexylbut-2-Enoate 28811-79-2

📜乙酰基环己烷置于sodium Hydride,二异丁基氢化铝体系中,用 四氢呋喃 用作溶剂,化学反应生成环丁烯酸
参考文献:铱催化 1,1-二烷基乙烯与乙醇的对映选择性转移氢化:范围和机制
标题:铱催化 1,1-二烷基乙烯与乙醇的对映选择性转移氢化:范围和机制
摘要:尽管过渡金属催化的不对称烯烃氢化领域取得了半个世纪的进步,但纯烷基取代的1,1-二烷基乙烯的对映选择性氢化仍然是一个未解决的挑战.在此,我们描述了一种手性 Pcn Ox-钳铱络合物,用于用乙醇对此类烯烃进行不对称转移氢化,提供全烷基取代的叔立体中心.在底物与仲/伯和伯/伯烷基组合的反应中可以实现高水平的对映选择性.该催化剂进一步应用于二取代烯醇的氧化还原异构化,产生远离所得羰基的叔立体中心.机理研究揭示了二氢化物 (Pcn Ox )Ir(H) 2作为催化活性中间体,可以衰变成二聚体 (κ 3-Pcn Ox )Irh(μ-H) 2 Irh(κ 2-Pcn) Ox ) 通过配体重金属化途径. H 2加氢条件下的催化剂失活比etoh转移加氢条件下的催化剂失活快得多,这解释了为什么(Pcn Ox )Ir催化剂对转移加氢有效但对加氢无效.通过区域选择性 1,2-插入抑制二取代到三取代的烯烃异构
Doi:10.1021/jacs.3C12985

专利信息

专利号:US-5629394-A
优先权日:1992-12-17
标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers
发明人：CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R
权利人:EXXON CHEMICAL PATENTS INC
摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

专利号:CN-116854744-A
优先权日:2023-06-13
标 题 :Synthesis and Application of Chiral Spiro[Chroman-4,1'-Indene]Bidentate Ligand Iridium Complex

专利号:US-5444135-A
优先权日:1992-12-17
标 题:Direct synthesis by living cationic polymerization of nitrogen-containing polymers