CAS: 23500-10-9; (S)-1-(2-Chloroacetyl)Pyrrolidine-2-Carboxylic Acid

上下游产品

CAS号79-04-9 氯乙酰氯 | CAS号147-85-3 脯氨酸 | CAS号79-11-8 氯乙酸 | CAS号2812-47-7 DL-脯氨酰胺 | CAS号214398-99-9 (S)-1-(2-氯乙酰基)吡... | CAS号274901-16-5 维达列汀 | CAS号207557-35-5 (2S)-N-氯乙酰基-2-氰基四氢吡咯 | CAS号704-15-4 甘油-l-脯氨酸

📜Dl-脯氨酰胺置于sodium Hydroxide,Amidase From Pig'S-Kidneys体系中,化学反应生成1-(2-氯乙酰基)脯氨酸
参考文献:Hamer; Greenstein,Journal Of Biological Chemistry,1951,Vol. 193,P. 81,87
标题:Hamer; Greenstein,Journal Of Biological Chemistry,1951,Vol. 193,P. 81,87

专利信息

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-5219741-A
优先权日:1989-09-06
标题:Method of making L-proline using an N-acyl-L-protine acylase
发明人：GROEGER ULRICH; LEUCHTENBERGER WOLFGANG; DRAUZ KARLHEINZ
权利人:DEGUSSA
摘要:A microbiologically produced, thermostable N-acylproline-acylase and a process for obtaining it from Comamonas testosteroni DSM 5416 and Alcaligenes denitrificans DSM 5417. The enzyme is useful for the synthesis of L-proline from various N-acyl-L-proline derivatives.

专利号:US-2008058528-A1
优先权日:2006-07-20
标题 :Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile

专利号:EP-2057145-B1
优先权日:2006-07-20
标 题:Synthesis of (2s,5r)-5-ethynyl-1-{n-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile

专利号:US-2016152600-A1
优先权日:2006-07-20
标题 :Synthesis of (2s,5r)-5-ethynyl-1-pyrrolidine-2-carbonitrile

专利号:US-9260411-B2
优先权日:2006-07-20
标 题 :Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
发明人：MCDERMOTT TODD S; WAGAW SEBLE H; ENGSTROM KENNETH M; GANDARILLA JORGE; KRUGER ALBERT; ROZEMA MICHAEL J; FICKES MICHAEL G; WITTENBERGER STEVEN J; BHAGAVATULA LAKSHMI; BORCHARDT THOMAS B
权利人:MCDERMOTT TODD S; WAGAW SEBLE H; ENGSTROM KENNETH M; GANDARILLA JORGE; KRUGER ALBERT; ROZEMA MICHAEL J; FICKES MICHAEL G; WITTENBERGER STEVEN J; BHAGAVATULA LAKSHMI; BORCHARDT THOMAS B; ABBVIE INC
摘要:A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.