Trans-咖啡酸置于rosmarinate Synthase体系中,用 四氢呋喃,水 用作溶剂,化学反应 5.5H,反应生成迷迭香酸 参考文献:Pabsch,K.; Petersen,M.; Rao,N. N.,Recueil Des Travaux Chimiques Des Pays-Bas,1991,Vol. 110,# 5,P. 199-205 标题:Pabsch,K.; Petersen,M.; Rao,N. N.,Recueil Des Travaux Chimiques Des Pays-Bas,1991,Vol. 110,# 5,P. 199-205
专利号:US-10604479-B2 优先权日:2013-11-18 标 题:Continuous process for the one-pot synthesis of metal salts and metal complexes 发明人:LEONARDI GIULIANO; GASPERONI GIOVANNI 权利人:VOLARE & CONNECTING LLC; LEONARDI GIULIANO; NOVUS INT INC 摘要:A continuous process is described for the one-pot synthesis of compounds, such as metal salts and metal complexes, as well as optionally for the protection of the compounds thus obtained by coating and/or impregnation with suitable compounds.
专利号:US-2004110228-A1 优先权日:2002-04-01 标 题:Combinatorial organic synthesis of unique biologically active compounds 发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M 摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.
专利号:US-5922335-A 优先权日:1995-05-15 标 题:Uses for ascorbyl-phosphoryl-cholesterol in topical compositions 发明人:PTCHELINTSEV DMITRI 权利人:AVON PROD INC 摘要:Novel uses of 3'-(L-ascorbyl-2-o-phosphoryl)-cholesterol, 3'-(L-ascorbyl-3-o-phosphoryl)-cholesterol, structural or functional isomers thereof and salts thereof (referred to collectively as 'APC compounds') are disclosed. Such novel uses include a method of reducing epidermal synthesis of abnormal elastin, especially epidermal synthesis of abnormal elastin that results from exposure to UV radiation. Also disclosed is a novel method of stimulating keratinocyte formation of triglycerides. In addition, a novel method of achieving antioxidant activity, both in the skin and also in topical compositions, is disclosed.
专利号:US-2008081082-A1 优先权日:2000-11-21 标题:Topical Skin Compositions, Their Preparation, and Their Use 发明人:ZIMMERMAN AMY C; DEPPA DEBRA J; O'TOOLE DEBORAH A; MAYNE JAMES R 权利人:ACCESS BUSINES GROUP INTERNAT 摘要:Topical skin compositions include a complex containing components to provide a defense against the various pathway mechanisms of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. The compositions may be administered by topically applying them in an amount to inhibit those mechanisms. The compositions and methods are directed to the prevention of the adverse or detrimental effects of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. Thus, the compositions according to the invention improve barrier function, inhibit elastase and collagenase, and/or promote synthesis of collagen and elastin.
专利号:US-2012237623-A1 优先权日:2009-12-04 标题 :Topical Compositions Containing Derris Scandens Benth and a Method of Treating Skin 发明人:PTCHELINTSEV DMITRI S; LUO XIAOCHUN 权利人:PTCHELINTSEV DMITRI S; LUO XIAOCHUN; AVON PROD INC 摘要:Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising extracts of a. Derris scandens Benth. plant. These compositions are effective in stimulating LOXL-1, activity, inhibiting calcineurin activity, and stimulating glycosaminoglycan synthesis in skin cells and can thus reduce age-related skin damage and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of skin aging and/or skin damage.
专利号:US-2008124409-A1 优先权日:2000-11-21 标题 :Topical Skin Compositions, Their Preparation, and Their Use 发明人:ZIMMERMAN AMY C; DEPPA DEBRA J; O'TOOLE DEBORAH A; MAYNE JAMES R 权利人:ACCESS BUSINESS GROUP INT LLC 摘要:Topical skin compositions include a complex containing components to provide a defense against the various pathway mechanisms of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. The compositions may be administered by topically applying them in an amount to inhibit those mechanisms. The compositions and methods are directed to the prevention of the adverse or detrimental effects of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. Thus, the compositions according to the invention improve barrier function, inhibit elastase and collagenase, and/or promote synthesis of collagen and elastin.
1: Kiani A, Torabi P, Mousavi ZE. Green recovery of phenolic compounds from almond hull waste using ultrasound-assisted extraction: phenolics characterization and antimicrobial investigation. J Food Sci Technol. 2024 Oct;61(10):1930-1942. doi: 10.1007/s13197-024-05969-3. Epub 2024 Mar 18. 2: Hou T, Sana SS, Jeyavani J, Li H, Boya VKN, Vaseeharan B, Kim SC, Zhang Z. Biomedical applications of chitosan-coated phytogenic silver nanoparticles: An alternative drug to foodborne pathogens. Int J Biol Macromol. 2024 Sep 12;280(Pt 1):135590. doi: 10.1016/j.ijbiomac.2024.135590. Epub ahead of print. 29(17):4216. doi: 10.3390/molecules29174216. 4: Xiao X, Wu F, Wang B, Cai Z, Wang L, Zhang Y, Yu X, Luo Y. Clerodendranthus spicatus (Thunb.) Water Extracts Reduce Lipid Accumulation and Oxidative Stress in the Caenorhabditis elegans. Int J Mol Sci. 2024 Sep 6;25(17):9655. doi: 10.3390/ijms25179655.
合成参考文献
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