专利号:US-5194602-A 优先权日:1988-04-08 标题 :9α-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids 发明人:BATISI JACOBUS N M; MARX ARTHUR F 权利人:GIST BROCADES NV 摘要:New 9α-hydroxy-17-methylene steroids are prepared by the introduction of a substituted 17-methylene group in 9α-hydroxyandrost-4-ene-3, 17-dione. n The resulting compounds are useful starting compounds in the synthesis of corticosteroids.
专利号:US-12336981-B2 优先权日:2010-09-03 标题 :Compounds and compositions for the inhibition of NAMPT 发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; DRAGOVICH Peter; GOSSELIN FRANCIS; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; ROTH BRUCE; SMITH CHASE C; WANG ZHONGGUO; YUEN PO-WAI; ZHENG XIAOZHANG 权利人:VALO HEALTH INC; GENENTECH INC 摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:IL-89880-A 优先权日:1988-04-08 标题:A9-Hydroxy-71-Methylene steroids, their preparation and use in the synthesis of Corsican steroids