CAS: 15489-90-4; [dihydrogen 3,7,12,17-Tetramethyl-8,13-Divinyl-2,18-Porphinedipropionato(2-)]Hydroxyiron

该化合物是黑褐色黑晶状化合物,是 heme的衍生物,特别是 heme 的氧化形式;主要由铁和Porphyrin组成,由中央铁原子组成,与Porphyrin环相协调;Hematin以其在各种生物过程中的作用而著称,特别是在血红蛋白和血红蛋白方面,它参与氧的运输和储存;该化合物在碱性溶液中溶解,但一般在水中溶解;Hematin在可见频谱中表现出强烈吸收,使其在光谱应用中有用;还用于生物化学研究和临床诊断,特别是在与血球病和其他血液失调有关的研究中;此外,Hemoblogin还可能参与其他含热化合物的合成,并因其与生物系统的互动而可能对药理学和毒理学产生影响;其稳定性和再活性受环境条件的影响,例如PH和温度的影响.

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    专利信息


    专利号:US-2006128930-A1
    优先权日:2004-12-03
    标题 :Synthesis of sterically hindered phenol based macromolecular antioxidants
    发明人:DHAWAN ASHISH; CHOLLI ASHOK L
    权利人:DHAWAN ASHISH; CHOLLI ASHOK L
    摘要:Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes polymerizing and alkylating a phenol containing monomer represented by the following structural formula: n n nto produce a sterically hindered polymeric macromolecular antioxidant. X, R 10 and q are as defined herein. The disclosed method is a simple, direct and economical process for the synthesis of sterically hindered polymeric macromolecular antioxidants.

    专利号:US-7678877-B2
    优先权日:2004-12-03
    标题 :Process for the synthesis of polyalkylphenol antioxidants
    发明人:YANG SUIZHOU; CHOLLI ASHOK L
    权利人:POLNOX CORP
    摘要:Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes partially etherifying, polymerizing and thermally rearranging a phenol containing monomer represented by the following structural formula: n nto produce a sterically hindered polymeric macromolecular antioxidant. X, R 10 and q are as defined herein. The disclosed method is a simple, direct and economical process for the synthesis of sterically hindered polymeric macromolecular antioxidants.

    专利号:US-9005895-B2
    优先权日:2010-06-21
    标题:Compositions, methods and kits for nucleic acid synthesis and amplification
    发明人:WOO CORA L; BERKMAN JENNIFER; YIM PRISCILLA W
    权利人:WOO CORA L; BERKMAN JENNIFER; YIM PRISCILLA W; LIFE TECHNOLOGIES CORP
    摘要:The present invention is directed to compositions, methods and kits useful for the synthesis of nucleic acid molecules. More specifically, compositions, methods and kits are provided for the amplification of nucleic acid molecules in a one-step RT-PCR procedure comprising one or more agents used to increase tolerance to PCR inhibitors.

    专利号:US-2004110228-A1
    优先权日:2002-04-01
    标 题:Combinatorial organic synthesis of unique biologically active compounds
    发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
    摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

    专利号:US-2006128939-A1
    优先权日:2004-12-03
    标题 :One pot process for making polymeric antioxidants
    发明人:KUMAR VIJAYENDRA; YANG SUIZHOU; CHOLLI ASHOK L
    权利人:KUMAR VIJAYENDRA; YANG SUIZHOU; CHOLLI ASHOK L
    摘要:Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes mono-deacetylating, polymerizing and deacetylating an aryl monomer represented by the following structural formula: n n nto produce a sterically hindered polymeric macromolecular antioxidant. X, R 10 and q are as defined herein. The disclosed method is a simple, direct and economical process for the synthesis of sterically hindered polymeric macromolecular antioxidants.

    专利号:US-6239137-B1
    优先权日:1995-07-21
    标 题:Salts of aminoimidazole carboxamide and 5 amino or substituted amino 1,2,3-triazole, induce apoptosis, inhibit DNA synthesis and control cyclooxygenase activity
    发明人:KARMALI RASHIDA A; WEHRMANN FELIX
    权利人:SAVVIPHARM INC
    摘要:Compositions and methods are described for the induction of apoptosis inhibition of DNA synthesis, and/or inhibiting COX-2 activity using an effective amount of salts of aminoimidazole carboxamide, 5 amino 1,2,3-triazoles or a combination of salts thereof.

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    1: Chen Y, Lv B, Wang W, Wu Y, Li D. Structure-switching G-quadruplex: An efficient CRISPR/Cas12a signal reporter for label-free colorimetric biosensing. Int J Biol Macromol. 2025 Mar
    21:142410. doi: 10.1016/j.ijbiomac.2025.142410. Epub ahead of print. 53(3):3000605251325183. doi: 10.1177/03000605251325183. Epub 2025 Mar 21.
    3: Aliouat H, Zhang D, Peng L, Huang J, Cheng H, Zhu J, Chen X, Xie N, Zhou W, Zhao S. Targeted DNA Nanomachine Enables Specific miRNA-Responsive Singlet Oxygen Amplification for Precise Cutaneous Squamous Cancer Therapy. Adv Sci (Weinh). 2025 Mar

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    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
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