CAS: 15160-31-3; (S)-4-Nitrophenyl 2-((Tert-Butoxycarbonyl)Amino)-3-(1H-Indol-3-yl)Propanoate

相似化合物

16624-64-9 14009-92-8 7535-56-0

上下游产品

CAS号100-02-7 对硝基苯酚 | CAS号13139-14-5 N-B°C-L-色氨酸 | CAS号33515-09-2 黄体生成激素释放激素(LHRH) | CAS号55749-98-9 BOMBESIN (8-14)

📜对硝基苯酚,N-叔丁氧羰基-L-色氨酸置于n,N'-二环己基碳二亚胺体系中,用 乙酸乙酯 用作溶剂,化学反应生成N-[(1,1-二甲基乙氧基)羰基]-L-色氨酸 4-硝基苯基酯
参考文献:Synthesis Of Glutamate Receptor Antagonist Philanthotoxin-433 (Phtx-433) And Its Analogs
标题:Synthesis Of Glutamate Receptor Antagonist Philanthotoxin-433 (Phtx-433) And Its Analogs
摘要:
Doi:10.1016/s0040-4020(01)85463-6

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.