CAS: 13893-53-3; Ac-94149

相似化合物

53940-82-2 53940-83-3 40963-14-2

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CAS号87-69-4 酒石酸 | CAS号563-80-4 甲基异丙基甲酮 | CAS号151-50-8 氰化钾 | CAS号143-33-9 氰化钠 | CAS号74-90-8 氢氰酸 | CAS号40963-14-2 2-氨基-2,3-二甲基丁酰胺 | CAS号115852-48-7 稻瘟酰胺

L-酒石酸置于氨体系中,用 水 用作溶剂,化学反应生成2-氨基-2,3-二甲基丁腈
参考文献:Process For The Resolution Of Certain Racemic Amino Nitriles
标题:Process For The Resolution Of Certain Racemic Amino Nitriles
摘要:这项发明是关于通过它们各自的酒石酸盐对某些取代的混合氨基腈进行选择性和同时的分离-消旋-分离的过程.该发明还涉及由上述氨基腈制备的某些已分离(旋光活性)氨基酰胺,以及由此制备的具有除草作用的取代氧代咪唑啉基烟酸和3-喹啉羧酸.

专利信息

专利号:US-7183443-B2
优先权日:2002-04-09
标 题 :Process for the preparation of enantiomerically enriched compounds
发明人：DASSEN BERNARDUS HENRICUS NICO; KAPTEIN BERNARDUS; BROXTERMAN QUIRINUS BERNARDUS
权利人:DSM IP ASSETS BV
摘要:Process for the preparation of enantiomerically enriched amino aldehydes and amino alcohols, wherein a corresponding enantiomerically enriched amino nitrile is subjected to hydrogenation in the presence of hydrogen, a hydrogenation catalyst, preferably a Pd-catalyst and a mineral acid. For the preparation of an amino aldehyde hydrogen preferably is present at a hydrogen-pressure between 0.1 and 2 MPa, in particular between 0.5 and 1 MPa. The amino aldehyde preferably is isolated in the form of a chemically and configurationally stable derivative. For the preparation of an amino alcohol, preferably at least during part of the hydrogenation hydrogen is present at a hydrogen-pressure between 2 and 10 MPa, in particular between 4 and 6 MPa. In a preferred embodiment the hydrogen-pressure initially is between 0.5 and 2 MPa and subsequently, after most of the nitrile starting material is converted, the hydrogen pressure is increased to a value between 2 and 10 MPa. The enantiomerically enriched nitrile starting material may a.o. be prepared by enzymatic resolution, classical resolution, resolution via preferential crystallization, diastereomeric synthesis, catalytic asymmetric synthesis or dehydratation of amino acid amides.

专利号:US-8629279-B2
优先权日:2008-12-09
标 题 :Process for manufacturing 5-formyl-pyridine-2,3-dicarboxylic acid esters
发明人：RACK MICHAEL; GEBHARDT JOACHIM; MENGES FREDERIK; KEIL MICHAEL; KLIMA RODNEY F; CORTES David; LEICHT ROBERT; ZECH HELMUT; SCHROEDER JOCHEN
权利人:RACK MICHAEL; GEBHARDT JOACHIM; MENGES FREDERIK; KEIL MICHAEL; KLIMA RODNEY F; CORTES David; LEICHT ROBERT; ZECH HELMUT; SCHROEDER JOCHEN; BASF SE
摘要:A process for manufacturing a 5-formyl-pyridine-2,3-dicarboxylic acid ester (I) wherein Z is hydrogen or halogen; Z 1 is hydrogen, halogen, cyano or nitro and R 1 , R 2 are independently C 1 -C 10 -alkyl, comprising the steps of (i) reacting a compound of formula (II), wherein the symbols are as in formula (I), with a nitrosation agent (III) R 3 —O—Nâ• O (III) wherein R 3 is C 1 -C 8 -alkyl, in the presence of an alkali metal or alkaline earth metal alcoholates or carbonates in a polar aprotic solvent at a temperature of from −45 to 40° C., to obtain an oxime compound (IV) where Z, Z 1 , R 1 and R 2 are as in formula (I), and (ii) reacting oxime compound (IV) with an aliphatic C 1 -C 10 -aldehyde in the presence of a Lewis acid at a temperature in the range of from 0 to 100° C. The compounds of formula (I) are useful intermediates in the synthesis of herbicidal imidazolinones, like imazamox.

专利号:US-8563734-B2
优先权日:2008-11-13
标题 :2-[1-cyanopropyl)carbamoyl]-5-chloromethyl nicotinic acids and the use thereof in manufacturing herbicidal imidazolinones
发明人：MENGES FREDERIK; GEBHARDT JOACHIM; RACK MICHAEL; KEIL MICHAEL; KLIMA RODNEY F; CORTES David; LEICHT ROBERT; ZECH HELMUT; SCHROEDER JOCHEN
权利人:MENGES FREDERIK; GEBHARDT JOACHIM; RACK MICHAEL; KEIL MICHAEL; KLIMA RODNEY F; CORTES David; LEICHT ROBERT; ZECH HELMUT; SCHROEDER JOCHEN; BASF SE
摘要:2-[(1-cyanopropyl)carbamoyl]-5-chloromethyl nicotinic acids of formula (I) where Z is hydrogen or halogen; Z 1 is hydrogen, halogen, cyano or nitro; R 1 is C 1 -C 4 alkyl; R 2 is C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl or R 1 and R 2 , when taken together with the atom to which they are attached, represent a C 3 -C 6 cycloalkyl group optionally substituted with methyl, and R 3 is hydrogen or a cation preferably selected from the group consisting of alkali metals, alkaline earth metals, manganese, copper, iron, zinc, cobalt, lead, silver, nickel, ammonium and organic ammonium; are useful intermediates for the synthesis of herbicidal imidazolinones.

专利号:US-9278977-B2
优先权日:2008-11-13
标 题 :Process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides
发明人：MENGES FREDERIK; GEBHARDT JOACHIM; RACK MICHAEL; KEIL MICHAEL; KLIMA RODNEY F; CORTES David; LEICHT ROBERT; ZECH HELMUT; SCHROEDER JOCHEN
权利人:BASF SE
摘要:A process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides (I) n n n n n n n n n n n n wherein n Z is hydrogen or halogen; n Z 1 is hydrogen, halogen, cyano or nitro; n comprising the steps of n (i) reacting a compound of formula (II), n n n n n n n n n n n n n n n n wherein the symbols have the meaning given in formula (I), with a chlorinating agent, optionally in the presence of a radical initiator in a solvent selected from halogenated hydrocarbons, n and n (ii) crystallizing the compound (I) formed in step (i) from a solvent selected from chlorobenzene, 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,4-dichlorobenzene, dichloroethane, trichloromethane, dichloromethane, toluene, xylenes, ethyl acetate, methyl tert.-butyl ether, and mixtures thereof. n n n n n Compounds (I) are useful intermediates in the synthesis of herbicidal imidazolinones.

专利号:WO-2010055042-A1
优先权日:2008-11-13
标 题:2-[(1-cyanopropyl)carbamoyl]-5-methoxymethyl nicotinic acids and the use thereof in manufacturing herbicidal imidazolinones
发明人：CORTES David
权利人:BASF SE; CORTES David
摘要:2-[(1 -cyanopropyl)carbamoyl]-5-methoxymethyl nicotinic acids of formula (I) where Z is hydrogen or halogen; Z 1 is hydrogen, halogen, cyano or nitro; R 1 is C 1 C 4 alkyl; R 2 is C 1 C 4 alkyl, C 3 -C 6 cycloalkyl or R 1 and R 2 , when taken together with the atom to which they are attached, represent a C 3 -C 6 cycloalkyl group optionally substituted with methyl, and R 3 is hydrogen or a cation preferably selected from the group consisting of alkali metals, alkaline earth metals, manganese, copper, iron, zinc, cobalt, lead, silver, nickel, ammonium and organic ammonium; are useful intermediates for the synthesis of herbicidal imidazolinones.

专利号:CN-101307014-A
优先权日:2007-05-17
标题 :Synthesis of N-(1-cyano-1,2-dimethylpropyl)-2-(2,4-dichlorophenoxy)propionamide