CAS: 129101-25-3; 2-((Tert-Butoxycarbonyl)Amino)-3-(4-Fluorophenyl)Propanoic Acid

相似化合物

169243-86-1 177966-64-2 18125-46-7

上下游产品

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile L-4-fluorophenylalanine tert-butyl dicarbonatedi-tert-butyl dicarbonate 4-FluorophenylalanineB°C-Phe(4-F)-NMeBzl

📜二碳酸二叔丁酯,Dl-对氟苯丙氨酸置于sodium Hydroxide体系中,用 1,4-二氧六环,水 用作溶剂,化学反应 0.5H,以100%的收率获得boc-Dl-4-氟苯丙氨酸
参考文献:使用staudinger反应固相合成β-内酰胺,通过19 F NMR光谱监测
标题:使用staudinger反应固相合成β-内酰胺,通过19 F NMR光谱监测
摘要:我们报告了使用19 F NMR作为监测固相反应的简单方法.在涉及氟化α-氨基酯,醛和酰氯的多组分反应的情况下,描述了包括保护,偶联,脱保护,缩合,环加成和裂解步骤在内的多步骤序列.
Doi:10.1016/s0040-4020(03)00553-2

专利信息

专利号:US-11453699-B2
优先权日:2017-04-19
标 题:Antimicrobial compounds and/or modulators of microbial infections and methods of using the same
发明人：SCOTT WILLIAM LEONARD; O'DONNELL MARTIN JAMES; SAMARITONI JACK GENO
权利人:UNIV INDIANA RES & TECH CORP
摘要:Some embodiments include compounds that can inhibit the growth of bacterial and/or inhibit or reduce microbial infections caused by one or more microorganisms (e.g., Pseudomonas aeruginosa and Cryptococcus neoformans) and methods of using these compounds to treat microbial infection and outbreaks and/or to reduce the formation of biofilms. Other embodiments include synthesis of the compounds that can inhibit the growth of one or more microorganisms and/or inhibit or reduce microbial infections.

专利号:US-6872745-B2
优先权日:2000-04-14
标 题 :Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
发明人：JOHNSON JR THEODORE O; HUA YE; LUU HIEP T; DRAGOVICH PETER S
权利人:AGOURON PHARMA
摘要:Compounds of the formula: n n nwhere the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.