CAS: 102-71-6; Triethanolamine

该化合物是化学配方C6H15NO3的有机化合物,是一种粘粘性,无色和淡黄色的黄液,具有湿度和色色,有温和的氨味;三乙醇胺是一种三功能性杀伤人员地雷,含三种氢氧基和一种铁矿,允许其在各种配方中作为表面活性剂,乳化剂和pH平衡剂发挥作用;可溶于水和酒精,使其在水体和非水体系统中都能使用. TEA通常用于个人护理产品,化妆品和药品,以稳定乳液并增强配方的质;此外,它作为工业应用中的腐蚀抑制剂,用于生产清洁剂;虽然一般认为低浓度安全,但可对某些人造成皮肤刺激和敏感,需要小心处理和配方做法.

结构式图片

物理性质

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报CoRAP评估清单REACH预注册

上下游产品

CAS号75-21-8 环氧乙烷 | CAS号141-43-5 2-氨基乙醇 | CAS号111-42-2 二乙醇胺 | CAS号7664-41-7 氨 | CAS号7529-23-9 TEA N-oxide | CAS号3002-18-4 三乙醇胺三乙酸 | CAS号97-64-3 乳酸乙酯 | CAS号616-29-5 1,3-二氨基-2-丙醇 | CAS号107-21-1 乙二醇 | CAS号105377-53-5 2-[bis(2-hydrox... | CAS号4097-89-6 三(2-氨基乙基)胺 | CAS号76228-29-0 | CAS号3189-13-7 6-甲氧基吲哚 | CAS号4837-90-5 4-甲氧基吲哚 | CAS号17422-32-1 5-氯吲哚 | CAS号42003-39-4 氯甲基杂氮硅三烷 | CAS号358-21-4 PERFLUORODIETHY...

合成工艺路线路线简述

  • 合成目标产物 Triethanolamine 主要起始原料 Ethylene Oxide And Monoethanolamine
  • (文献来源)合成步骤主要原料 Ethylene Oxide 和 Monoethanolamine
Sodium Chlorite 反应生成三乙醇胺
参考文献:Aqueous Composition And Method Of Producing Chlorine Dioxide Using Aqueous Composition
标题:Aqueous Composition And Method Of Producing Chlorine Dioxide Using Aqueous Composition
摘要:一种水性组合物包括一个活化剂,一个亚氯酸盐离子源和水.该水性组合物呈碱性.该水性组合物在与酸接触时产生二氧化氯.生产二氧化氯的方法包括将水性组合物与酸接触.

专利信息


专利号:US-12383499-B2
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
发明人:NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
权利人:UNIV CALIFORNIA
摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

专利号:US-9561498-B2
优先权日:2012-04-27
标 题 :Process for the direct synthesis of Cu-SAPO-34
发明人:FRANCO RAQUEL MARTINEZ; MARIN MANUEL MOLINER; CANÓS AVELINO CORMA; KUSTOV ARKADY; THØGERSEN JOAKIM REIMER
权利人:FRANCO RAQUEL MARTINEZ; MARIN MANUEL MOLINER; CANÓS AVELINO CORMA; KUSTOV ARKADY; THØGERSEN JOAKIM REIMER; HALDOR TOPSOE AS
摘要:A process for the direct synthesis of Cu-SAPO-34 comprising at least the steps: preparation of a mixture of water, at least one silicon source, at least one Al source, at least one P source, at least one Cu source, at least one 0SDA1 (any polyamine), and at least one OSDA2 source (where OSDA2 is any organic molecule capable of directing the synthesis of SAPO 34); and where the final synthesis mixture has the molar composition: a Si:0.5 Al:c Cu:d OSDA1:e OSDA2:f H2O wherein a is in the range from 0.01 to 0.3; b is in the range from 0.2 to 0.49; c is in the range from 0.001 to 0.6; d is in the range from 0.001 to 0.6; e is in the range from 0.001 to 2; f is in the range 1 to 200; hydrothermal treatment of the mixture at 80−200° C. until formation of the crystalline material, and recovery of the crystalline material.

专利号:US-2021130543-A1
优先权日:2019-10-30
标 题:Synthesis of cyanurate and multifunctional alcohol-based polyether acrylate for uv curable materials
发明人:YUAN ZHONGSHUN; XU CHUNBAO; WU WEI
权利人:YUAN ZHONGSHUN; XU CHUNBAO; WU WEI
摘要:Polyether (meth)acrylates based on cyanuric acid or substituted cyanuric acid and multifunctional alcohol, which optionally include triethanolamine units, have wide applications in UV curable adhesives, coatings, inks, sealants, paints or 3D printing. These polyether acrylates have rigid cyanurate structure endowing the material with extra strength and thermal stability. Furthermore, triethanolamine unit, when present, endows the material with anti-oxygen inhibition property in UV curing process. These polyether (meth)acrylates have low viscosity and high reactivity towards UV curing. The cured resins have high resilience and strength. The process of making the polyether (meth)acrylates includes the synthesis of trifunctional polyether polyols through controlled polymerization of propylene oxide using multifunctional alcohol (such as glycerol and sucrose), cyanuric acid or substituted cyanuric acid, and optionally triethanolamine, in the presence of a catalyst, followed by the synthesis of polyether (meth)acrylates through transesterification or through direct esterification of the trifunctional polyether polyols.

专利号:US-3963770-A
优先权日:1972-09-27
标 题:Synthesis of ortho-chlorobenzalmalononitrile
发明人:KNAPP JOHN S
权利人:FEDERAL LAB INC
摘要:Disclosed herein is a synthesis of ortho chlorobenzalmalononitrile by reacting malononitrile with ortho-chloro benzaldehyde in methanol in the presence of a basic catalyst; separating the product crystals from the methanol; washing the crystals with fresh methanol; combining the wash methanol with the methanol filtrate and using the combined methanol in another similar synthesis run and repeating a series of such runs; drying the crystals with a current of turbulent dry air and scrubbing the air with base solution thereby substantially reducing associated problems of effluent treatment and ambient air pollution.

专利号:US-9278972-B2
优先权日:2011-12-23
标题 :Synthesis of triazolopyrimidine compounds
发明人:MARAS NENAD; GAZIC SMILOVIC IVANA; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:US-9950988-B2
优先权日:2012-12-26
标题:Method for the synthesis of alpha/alpha-prime-alcoxylated glycerol linear carbonic esters
发明人:LEISING FRéDéRIC; MOULOUNGUI ZéPHIRIN
权利人:CHRYSO; INST NAT POLYTECHNIQUE TOULOUSE; INST NAT DE LA RECH AGRONOMIQUE INRA
摘要:A method for the synthesis of α/α′-alcoxylated glycerol linear carbonic esters, wherein the following are brought into contact at a reaction temperature lower than 220° C.: a quantity of at least one precursor selected from the group consisting of α/α′-alcoxylated glycerol cyclo-carbonates; a quantity of at least one catalyst selected from the group consisting of metal oxides, Lewis acids, organometallic catalysts and mineral bases; and a quantity of at least one organic primer. A composition containing at least one novel α/α′-alkoxylated glycerol linear carbonic ester.
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主要参考文献


1: Trolamine: over-the-counter. Prescrire Int. 2010 Apr;19(106):64. 81(3):209-14. 81(2):558-567. doi: 10.1016/j.jaad.2019.02.047. Epub 2019 Feb 22.
26:e2929. doi: 10.1590/1518-8345.2035.2929. Epub 2018 May 7.
5: Lu S, Lu A, Paslin D. A Comparison of the Wound Healing Efficacy of Trolamine Emulsion, Manuka Gel, and Polymyxin-Bacitracin Ointment. Adv Skin Wound Care. 2020 Apr;33(4):217-220. doi: 10.1097/01.ASW.0000655468.08618.fc. 7(7):CD012171. doi: 10.1002/14651858.CD012171.pub2.

合成参考文献


参考文献:10.1021/bm100007s
摘要:Pang Y, Zhu Q, Liu J, Wu J, Wang R, Chen S, Zhu X, Yan D, Huang W, Zhu B. Design and synthesis of cationic drug carriers based on hyperbranched poly(amine-ester)s. Biomacromolecules. 2010 Mar 08;11(3):575–82. doi: 10.1021/bm100007s.
参考文献:10.1016/j.ijpharm.2010.02.014
摘要:Dicko A, Kwak S, Frazier AA, Mayer LD, Liboiron BD. Biophysical characterization of a liposomal formulation of cytarabine and daunorubicin. International Journal of Pharmaceutics. 2010 May;391(1-2):248–59. doi: 10.1016/j.ijpharm.2010.02.014.
参考文献:10.1007/s10295-005-0062-3
摘要:Liu Y, Sha Q, Wu S, Wang J, Yang L, Sun W. Enzymatic resolution of racemic phenyloxirane by a novel epoxide hydrolase from Aspergillus niger SQ-6 and its fed-batch fermentation. Journal of Industrial Microbiology & Biotechnology. 2005 Dec 01;33(4):274–82. doi: 10.1007/s10295-005-0062-3.
参考文献:10.1208/s12249-011-9661-7
摘要:Badıllı U, Sen T, Tarımcı N. Microparticulate based topical delivery system of clobetasol propionate. AAPS PharmSciTech. 2011 Sep;12(3):949–57.
参考文献:10.4137/aci.s6969
摘要:Salem AA, Soliman AA, El-Haty IA. New spectrophotometric method for determining nitrogen dioxide in air using 2,2-azino-bis(3-ethyl benzothiazoline)-6-sulfonic acid-diammonium salt and passive sampling. Anal Chem Insights. 2011;6():37–44.
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