专利号:US-4422970-A 优先权日:1982-05-20 标题 :Method of synthesis of 1-dodecylazacycloheptan-2-one 发明人:RAJADHYAKSHA VITHAL J; PECK JAMES V; MINASKANIAN GEVORK 权利人:NELSON RES & DEV 摘要:In a method of synthesis of 1-substituted azacycloalkan-2-ones with primary alkyl halides and aralkyl halides as alkylating agents, the improvement comprising carrying out the N-alkylation in the presence of a phase transfer catalyst having the structural formula where X is suitable anion; and R1, R2, R3 and R4 are each alkyl or aralkyl groups having 1-18 carbon atoms, or R2, R3 and R4 can form a part of a heterocyclic ring, with the proviso that the combined total of carbon atoms is between 16 and 40.
专利号:US-5455157-A 优先权日:1989-05-22 标 题:Method for the non-radioactive measurement of the nucleic acid synthesis in eukaryotic cells 发明人:HINZPETER MATTHIAS; ELTZ HERBERT VON DER 权利人:BOEHRINGER MANNHEIM GMBH 摘要:For the determination of the rate of nucleic acid synthesis in eukaryotic cells a nucleotide which is non-radioactively labelled or derivatized with a hapten is introduced into the cells with the addition of liposomes and the rate of synthesis of the nucleic acids is determined by means of the incorporation of the nucleotide via its label or derivatization.
专利号:US-8211205-B1 优先权日:2009-07-28 标题:Method of controlled synthesis of nanoparticles 发明人:DIDENKO YURI TROFIMOVICH; NI YUHUA 权利人:DIDENKO YURI TROFIMOVICH; NI YUHUA; UT DOTS INC 摘要:A method for the synthesis and manufacture of metal nanoparticles using metal inorganic salts. The method is simple and uses inexpensive chemicals. The procedure produces nanometals in 100% yields. Method is scalable and produces nanoparticles in unlimited quantities. In this method, a metal inorganic salt is dissolved in a reaction medium, comprised of a solvent and organic amine to create a metal/amine complex. A reducing agent, comprised of a solvent and Sodium Borohydride (NaBH 4 ), is then mixed with the metal/amine complex through titration or through a continuous flow process. The resulting nanoparticles are then precipitated through the addition of methanol and centrifugation and decanted. The decanted nanoparticles can then be suspended in a solvent for storage.
专利号:WO-2025017286-A1 优先权日:2023-07-14 标 题 :Novel synthesis of colloidal quantum dot ink and applications in semiconductor devices 发明人:VASHISHTHA PARTH; HE XIN; MEHTA JOSHUA; LIU JUNPENG; VO CONG-DUAN 权利人:QUANTUM SCIENCE LTD 摘要:The present invention provides a method for producing a nanocrystal composition comprising an inorganic ligand via a one-pot synthesis. The present invention also provides nanocrystals comprising novel inorganic ligands and the use of these nanocrystals. The present invention further provides the use of the novel inorganic ligands in the preparation of nanocrystals.
专利号:US-2006154380-A1 优先权日:2004-06-23 标题:Synthesis of ordered arrays from gold clusters 发明人:EGUSA SHUNJI; JIN RONGCHAO; SCHERER NORBERT F 权利人:EGUSA SHUNJI; JIN RONGCHAO; SCHERER NORBERT F 摘要:A nanocluster includes 1 to 7 metal atoms and has at least one ligand, which is associated with at least one of the metal atoms. A method of making a nanocluster consists of combining a nanoparticle, a ligand and a high boiling point solvent to provide a mixture and heating the mixture at a temperature of at least about 125° C. to form a nanocluster with 1 to 7 metal atoms. An ordered array of nanostructures includes a substrate and a plurality of nanostructures on the substrate, where the nanostructures are made by forming a solution of nanoclusters, depositing the solution on a substrate, and heating the substrate.
专利号:US-2024123076-A1 优先权日:2021-02-08 标题:Unsaturated dendrimers compositions, related formulations, and methods of use thereof 发明人:LEE SANG M; SIEGWART DANIEL J 权利人:UNIV TEXAS 摘要:Described herein are novel lipid compositions comprising unsaturated dendrimers and methods of synthesis of unsaturated dendrimers. The lipid composition can comprise an ionizable cationic lipid, a phospholipid, and a selective organ targeting lipid. Also described herein are pharmaceutical formulations comprising an unsaturated dendrimer, a lipid composition, and a therapeutic agent. Further described in here are methods of mRNA delivery comprising a lipid composition and a therapeutic agent. Further described herein are high-potency dosage forms of a therapeutic formulated with a lipid composition.
参考文献:10.1385/1-59259-798-x:001 摘要:Lucy CA, Baryla NE, Yeung KK. Surfactant-based methods for prevention of protein adsorption in capillary electrophoresis. Methods Mol Biol. 2004;276():1–14. doi: 10.1385/1-59259-798-x:001. 参考文献:10.1038/ncomms4882 摘要:Jia L, Zhao G, Shi W, Coombs N, Gourevich I, Walker GC, Guerin G, Manners I, Winnik MA. A design strategy for the hierarchical fabrication of colloidal hybrid mesostructures. Nat Commun. 2014 May 27;5():3882. doi: 10.1038/ncomms4882.