📜Cuban-1,4-Dicarbonsaeure-Di-Tert-Butylperester 反应生成立方烷 参考文献:Proton Magnetic Resonance Spectra Of Cubane Derivatives. I. Syntheses And Spectra Of Mono-And 1,4-Disubstituted Cubanes 标题:Proton Magnetic Resonance Spectra Of Cubane Derivatives. I. Syntheses And Spectra Of Mono-And 1,4-Disubstituted Cubanes 摘要: Doi:10.1021/ja00427A003
专利信息
专利号:US-6660305-B1 优先权日:1998-07-28 标题 :Composition for stimulating the synthesis of the melanic pigment and process for obtaining it 发明人:CAO CARLOS M MIYARES 权利人:CT DE HISTOTERAPIA PLACENTARIA 摘要:This invention relates to the field of human medicine, more specifically to dermatology, and in particular to a composition developed for the stimulation of the synthesis of the melanic pigment of the skin, therefore useful for the treatment of vitiligo. The technical goal of this invention is to provide a composition of natural origin useful in the treatment of vitiligo that has no toxic effects and no relapse. The composition obtained stimulates the synthesis of the melanic pigment of the skin and the reproduction of melanocytes, as demonstrated through pharmacological tests to which the composition was subjected, causing no serious secondary reactions at all, as demonstrated in the toxicological, teratological and clinical tests performed. The resulting product can easily be obtained and applied, repigmentation begins rapidly after initiating the treatment, and the effect is irreversible. The color acquired is identical to the color of the normal skin areas of the patient, but these areas do not further increase the intensity of their coloration after the product has been applied. The product can also be used for the treatment of any depigmentation process of the skin, for example, that caused by burns.
专利号:US-2019228842-A1 优先权日:2017-11-17 标 题 :Recipe for the synthesis of metastable structures using topologically assembled precursors 发明人:JENA PURUSOTTAM; FANG HONG 权利人:UNIV VIRGINIA COMMONWEALTH 摘要:Methods of planning and executing the synthesis of metastable materials are provided. Topologically assembled precursors having potential energy surfaces in which the volumes of potential wells of certain local minima are increased are created in silico. The precursor molecules are used to synthesize, e.g. two-dimensional metastable carbon materials such as penta-graphene comprised entirely of pentagons, O-graphene comprised of five- and eight-membered rings, and R-graphene comprised of four-, six- and eight-membered rings.
专利号:US-2007074541-A1 优先权日:2003-10-10 标 题:Synthesis of germanium sulphide and related compounds 发明人:BADDING JOHN V; HEWAK DANIEL W; HUANG CHUNG-CHE 权利人:UNIV SOUTHAMPTON 摘要:The invention relates to synthesis of germanium sulphide glasses and optical devices formed therefrom. In a chemical vapour deposition process, germanium tetrachloride is reacted with hydrogen sulphide at temperatures in the range 450-700° C. to form germanium sulphide. Lower temperatures within this range of 450-550° C. directly produce a glass, whereas higher temperatures within the range of 600-700° C. produce a crystalline powder which can then be reduced to a glass by subsequent melting and annealing. The reaction is preferably carried out at atmospheric pressure or slightly higher. Thin films and bulk glasses suitable for optical waveguides can be formed directly in one processing step as can powders and microspheres. The materials synthesised are of a high purity with low oxide impurities and only trace levels of transition metal ions.
专利号:US-9061917-B2 优先权日:2010-08-11 标题:Combinatorial synthesis of the diamond unit cell 发明人:HODES DANIEL 权利人:HODES DANIEL; UNIT CELL DIAMOND LLC 摘要:A combinatorial synthesis of the diamond unit cell is disclosed wherein a carbon atom free of meta-stable radical impurities reacts with cyclic hydrocarbon compounds or heterocyclic compounds whose structure is tetrahedral or nearly tetrahedral. Reactions conducted in the vapor phase and in the solid state are disclosed.
专利号:US-8778295-B2 优先权日:2010-08-11 标 题 :Combinatorial synthesis of diamond 发明人:HODES DANIEL 权利人:HODES DANIEL 摘要:Disclosed is a combinatorial synthesis of Diamond wherein a first reactive species is produced by catalytic treatment of Acetylene, a second reactive species is produced by decomposition of a hydrocarbon source having a low Hydrogen-to-Carbon ratio using a high energy discharge, and the two reactive species so obtained are combined in the vapor phase to yield Diamond without the need of post-treatments. The reaction is efficient and affords Diamond under mild conditions with high purity such that it may be useful for producing Diamond for semiconductor and microelectronics applications.
专利号:US-2006130165-A1 优先权日:2004-12-09 标 题:F066 transgenic mice that express pathogenic mutants of the sca2 gene 发明人:AGUIAR SANTIAGO JORGE A; FERNANDEZ MASSO JULIO R; MENDOZA MARI YSSEL; VAZQUEZ MARCOS MARIA M; CRUZ LEON SILIAN; VELAZQUEZ PEREZ LUIS C; HERRERA MARTINEZ LUIS S 权利人:AGUIAR SANTIAGO JORGE A; FERNANDEZ MASSO JULIO R; MENDOZA MARI YSSEL; VAZQUEZ MARCOS MARIA M; CRUZ LEON SILIAN; VELAZQUEZ PEREZ LUIS C; HERRERA MARTINEZ LUIS S 摘要:The present invention is related with the neurobiology and the transgenic animals, more specifically with obtaining a model to study the SCA2 genetic disease. The genome of one mice line has been modified through the introduction of a DNA segment that contains the necessary information for the synthesis of the human ataxin 2. In particular the invention is related with the transgenic mice F066 and the cellular lines able to express the human sca2 gene under the regulation of its self promoter. The F066 transgenic mice reproduce the features of the disease. The homozygous transgenic mouse line for the new gene was obtained through matting. This transgenic line is useful to study the mechanism that produce the disease and also will permit to prove new therapeutics that contributes to minimize the clinical symptoms in the patients.
摘要:Pérez A, Roberts RE, Sanderson M, Reininger B, Aguirre-Flores MI. Disturbed sleep among adolescents living in 2 communities on the Texas-Mexico border, 2000-2003. Prev Chronic Dis. 2010 Mar;7(2):A40. 参考文献:10.3897/zookeys.101.1133 摘要:Breure AS. Annotated type catalogue of the Orthalicoidea (Mollusca, Gastropoda) in the Royal Belgian Institute of Sciences, Brussels, with descriptions of two new species. Zookeys. 2011;(101):1–50. 参考文献:10.5402/2011/292951 摘要:Solares AM, Baladron I, Ramos T, Valenzuela C, Borbon Z, Fanjull S, Gonzalez L, Castillo D, Esmir J, Granadillo M, Batte A, Cintado A, Ale M, Fernandez de Cossio ME, Ferrer A, Torrens I, Lopez-Saura P. Safety and Immunogenicity of a Human Papillomavirus Peptide Vaccine (CIGB-228) in Women with High-Grade Cervical Intraepithelial Neoplasia: First-in-Human, Proof-of-Concept Trial. ISRN Obstetrics and Gynecology. 2011 Mar 24;2011():1–9. doi: 10.5402/2011/292951. 参考文献:10.1590/s0036-46652010000400006 摘要:Valdés AF, Martínez JM, Lizama RS, Gaitén YG, Rodríguez DA, Payrol JA. In vitro antimalarial activity and cytotoxicity of some selected cuban medicinal plants. Rev Inst Med Trop Sao Paulo. 2010 Jul;52(4):197–201. doi: 10.1590/s0036-46652010000400006. 参考文献:10.1093/tropej/fmr060 摘要:Llanes R, Millan LM, Escobar MP, Gala A, Capo V, Feliciano O, Gutierrez O, Llop A, Ponce F, Perez-Perez GI. Low Prevalence of Helicobacter pylori Among Symptomatic Children from a Hospital in Havana, Cuba. Journal of Tropical Pediatrics. 2011 Jul 13;58(3):231–4. doi: 10.1093/tropej/fmr060.