CAS: 1285702-20-6; (5-(4-(((5-Methylfuran-2-yl)Methyl)Amino)Quinazolin-6-yl)Furan-2-yl)Methanol

主要参考文献

1: Panicker PS, Melge AR, Biswas L, Keechilat P, Mohan CG. Epidermal growth factor receptor (EGFR) structure-based bioactive pharmacophore models for identifying next-generation inhibitors against clinically relevant EGFR mutations. Chem Biol Drug Des. 2017 Oct;90(4):629-636. doi: 10.1111/cbdd.12977. Epub 2017 May 3. 2010–.

合成参考文献

参考文献:10.1124/mol.119.115964
摘要:Lee TD, Lee OW, Brimacombe KR, Chen L, Guha R, Lusvarghi S, Tebase BG, Klumpp-Thomas C, Robey RW, Ambudkar SV, Shen M, Gottesman MM, Hall MD. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology. 2019 Nov;96(5):629–40. doi: 10.1124/mol.119.115964.
参考文献:10.1021/acs.jmedchem.1c00985
摘要:Qin Z, Qin L, Feng X, Li Z, Bian J. Development of Cdc2-like Kinase 2 Inhibitors: Achievements and Future Directions. J Med Chem. 2021 Sep 23;64(18):13191–211. doi: 10.1021/acs.jmedchem.1c00985.