CAS: 101601-80-3; 2-Phenylpyridin-3-Amine
该化合物是一种环环环芳烃化合物,其2位置为苯基核心,在2位置为一苯基组,3位置为一苯基组,这一结构具有独特的电子和消毒特性,使其成为有机合成和制药研究的宝贵中间体,其矿藏功能允许进一步衍生,能够开发离心,催化剂和生物活性分子.该化合物的僵硬芳香框架有助于稳定性和可预测的再活动,有利于医药化学的应用,特别是在动脉抑制剂和其他治疗剂的设计方面.其定义明确的合成路线和纯度使它成为先进的化学研究的可靠建筑.
- 英文名称2-Phenylpyridin-3-Amine
- 中文名称2-苯基-3-氨基吡啶
- IUPAC名称2-phenylpyridin-3-amine
- 其它别名2-苯基-3-氨基吡啶3-Amino-2-Phenylpyridine; 3-Amino-2-Phenylpyridine
- CAS编号101601-80-3
- MFCD编号:MFCD04114113
- EINECS号:692-800-7
- 分子式:C11H10N2分子量:170.21
- 产品CID: 29758
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
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134896-35-8 219121-62-7 886508-73-2物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
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- 合成目标产物 3-Amino-2-Phenylpyridine 主要起始原料 2,4,6-Triphenylboroxin And 2-Chloro-3-Pyridinamine
- (文献来源)合成步骤主要原料 2,4,6-Triphenylboroxin 和 2-Chloro-3-Pyridinamine
📜在 氨体系中,用 甲醇 用作溶剂,化学反应生成2-苯基-3-氨基吡啶
参考文献:New Functionalised Silicas For Highly Selective Cation Exchange Spe Purification In Medicinal Chemistry
标题:New Functionalised Silicas For Highly Selective Cation Exchange Spe Purification In Medicinal Chemistry
摘要:Functionalised Silicas 2 And 3 Are Effective For The Cation Exchange Spe Purification Of Basic Molecules Containing Acid-Sensitive Functionalities,The Selective Separations Of Mixtures Of Basic Compounds And Accelerated Reaction Work-Ups/product Isolations. (C) 2008 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2008.05.087
专利信息
专利号:US-5232929-A
优先权日:1990-11-28
标 题 :3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
发明人：DESAI MANOJ C; ROSEN TERRY J
权利人:PFIZER
摘要:The present invention relates to novel 3-aminopiperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , Y and m are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of the formula I.
专利号:CA-2518447-A1
优先权日:2003-03-17
标 题 :Synthesis of aryl-substituted piperidines by hydrogenation of aryl-substituted pyridines
专利号:EP-1606257-A1
优先权日:2003-03-17
标 题 :Synthesis of aryl-substituted piperidines by hydrogenation of aryl-substituted pyridines
专利号:WO-2004083181-A1
优先权日:2003-03-17
标 题 :Synthesis of aryl-substituted piperidines by hydrogenation of aryl-substituted pyridines
专利号:JP-2006523205-A
优先权日:2003-03-17
标 题:Synthesis of aryl-substituted piperidines by hydrogenation of aryl-substituted pyridines.
专利号:US-5332817-A
优先权日:1990-01-04
标题 :3-aminopiperidine derivatives and related nitrogen containing heterocycles
发明人：DESAI MANOJ C; ROSEN TERRY J
权利人:PFIZER
摘要:The present invention relates to novel 3-amino-piperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , Y and m are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of the formula I.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 327.
摘要:Gosmini, C.; Corpet, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 663.
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