CAS: 799775-81-8; Butane-2,2-Diol

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        专利号:US-8822625-B2
        优先权日:2010-01-07
        标 题 :Method for providing higher molecular weight natural oil polyols without loss of functionality
        发明人:GARRETT THOMAS M; DU XIAN XIAN
        权利人:GARRETT THOMAS M; DU XIAN XIAN; MCPU POLYMER ENGINEERING LLC
        摘要:Methods of one-pot synthesis of high molecular weight natural oil polyols having a functionality of at least two are provided. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.

        专利号:US-8865854-B2
        优先权日:2010-01-07
        标 题:Method of synthesizing tuneably high functionality in high molecular weight natural oil polyols
        发明人:GARRETT THOMAS M; DU XIAN XIAN
        权利人:GARRETT THOMAS M; DU XIAN XIAN
        摘要:Methods of one-pot synthesis of high molecular weight natural oil polyols having a functionality of between about 4 and about 8 are provided. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.

        专利号:US-7498434-B2
        优先权日:2004-01-14
        标题:Two-phase method for the synthesis of selected pyrazolopyrimidines
        发明人:CANTRELL GARY LEE; MOSER FRANK WILLIAM; HALVACHS ROBERT EDWARD
        权利人:MALLINCKRODT INC
        摘要:An improved method of making a substituted pyrazolopyrimidine. The method comprises reacting a aminopyrazole compound or a salt thereof with a substituted 1-oxo-2-propenyl-arene(-heterocycle) or a salt thereof under acidic conditions in a reaction medium including a two-phase mixture of an aqueous solution and a water-immiscible organic liquid. Specific substituted pyrazolopyrimidines include N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide and N-methyl-N-(3-{3-[2-thienyl-carbonyl]-pyrazolo[1,5-a]-pyrimidin-7-yl}phenyl)acetamide.

        专利号:US-2005175556-A1
        优先权日:2004-02-07
        标题 :Skin Darkening (Sunless Tanning) Compositions Based on Enhancement of Melanin Synthesis by Tyrosinase Promoters
        发明人:GUPTA SHYAM K
        权利人:BIODERM RESEARCH
        摘要:This invention discloses skin darkening (sunless tanning) compositions based on enhancement of melanin synthesis by tyrosinase enzyme by providing essential substrates for tyrosinase as well as the essential elements to activate the active-site of tyrosinase enzyme. These compositions thus also act as promoters of tyrosinase enzyme.

        专利号:US-11529370-B2
        优先权日:2017-11-24
        标 题 :Use of composition comprising stem cell-derived exosome as effective ingredient in strengthening skin barrier and improving skin barrier function
        发明人:YI YONG WEON; CHO BYONG SEUNG
        权利人:EXOCOBIO INC
        摘要:A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and/or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.

        专利号:US-11529298-B2
        优先权日:2019-08-28
        标题:Cosmetic composition and its use, dermocosmetic formulation
        发明人:CARDOSO DE LIMA ERINE; BEZERRA TALITHA FARINA; FELIPE DE OLIVEIRA STEHLING LUIZ; MASIERO SILVANA
        权利人:LUXBIOTECH FARM LTDA
        摘要:The present invention relates to dermocosmetic formulations for use in combating skin aging, especially photoaging. The present invention promotes the increase of the synthesis of collagen, elastin and glycosaminoglycans (GAG), in addition to significantly increase the activity of the superoxide dismutase enzyme (SOD) and the cell proliferation.

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        参考文献:10.1007/978-3-642-24688-3_13
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