CAS: 589-16-2; 4-Ethylaniline

上下游产品

CAS号99-92-3 4-氨基苯乙酮 | CAS号100-13-0 4-硝基苯乙烯 | CAS号1520-21-4 4-乙烯基苯胺 | CAS号937-31-5 4-硝基苯乙炔 | CAS号14235-81-5 4-乙炔基苯胺 | CAS号1585-07-5 1-溴-4-乙基苯 | CAS号100-19-6 对硝基苯乙酮 | CAS号371153-68-3 benzyl N-(4-eth... | CAS号6531-13-1 1-(4-硝基苯基)乙醇 | CAS号67302-67-4 N-benzylidene-4... | CAS号109240-32-6 N-Benzyl-4-ethy... | CAS号111299-89-9 2-(4-ethylpheny... | CAS号4946-13-8 4-乙基苯硫酚 | CAS号37033-93-5 5-乙基吲哚-2-羧酸 | CAS号5707-44-8 4-乙基联苯 | CAS号14618-46-3 Acetamide, N-(4... | CAS号142458-15-9 methyl 4-(4-eth... | CAS号123-07-9 4-乙基苯酚 | CAS号459-47-2 1-乙基-4-氟苯

4-硝基苯乙烯置于palladium Diacetate Potassium Fluoride,Polymethylhydrosiloxane体系中,用 四氢呋喃 作为反应溶剂,化学反应 0.5H,以100%的收率获得产物4-乙基苯胺
参考文献:一锅法将硝基化合物转化为胺,羟胺,酰胺,磺胺和氨基甲酸酯的钯催化硅烷/硅氧烷还原
标题:一锅法将硝基化合物转化为胺,羟胺,酰胺,磺胺和氨基甲酸酯的钯催化硅烷/硅氧烷还原
摘要:醋酸钯 (II),氟化钾水溶液和聚甲基氢硅氧烷 (Pmhs) 的组合有助于在室温下将芳香族硝基化合物还原为苯胺.这些反应往往快速(30 分钟),高产,并且可以耐受一系列其他官能团.用三乙基硅烷代替 Pmhs/kf 可以将脂肪族硝基化合物还原为相应的羟胺.根据底物的不同,这两种条件都可以将产物胺原位转化为酰胺,磺酰胺和氨基甲酸酯.
DOI:10.1055/s-2006-950231

专利信息

专利号:US-9815771-B2
优先权日:2014-08-06
标题 :Method for the synthesis of mirabegron and its derivatives
发明人：MARQUILLAS OLONDRIZ FRANCISCO; RIEGO ARBOLEYA ESTELA
权利人:INTERQUIM SA
摘要:The present invention refers to a method for the synthesis of a compound of formula (I), solvates, stereoisomers or salts thereof, a key intermediate in the synthesis of Mirabegron by reduction of an amide in the presence of an amine-boranecomplex, wherein the amine is an aniline.

专利号:US-9221821-B2
优先权日:2012-06-05
标题:Methods for the synthesis of 1,3-substituted aminouracils and other xanthine-related compounds
发明人：DIEP NHUT; KALYAN YURIY B
权利人:FOREST LAB HOLDINGS LTD; FOREST LAB HOLDINGS LTD
摘要:Methods for the synthesis of disubstituted aminouracils and xanthine and/or xanthine-related compounds are provided.

专利号:US-5189206-A
优先权日:1989-03-16
标题 :Process for the preparation of aminobenzenesulfonic acids
发明人：HERZIG PAUL
权利人:CIBA GEIGY CORP
摘要:There is disclosed a process for the preparation of compounds of formula ##STR1## wherein the symbols are as defined in claim 1, which process comprises dissolving a compound of formula ##STR2## in sulfuric acid, adding this solution to oleum and reacting the mixture in the temperature range from 10° to 80° C. until a sulfo group has been completely introduced, and, in an optional further step, subjecting the reaction mixture to further reaction in the temperature range from 100° to 200° C. to introduce a second sulfo group. n The compounds of formula (1) obtainable by this process are useful intermediates for the synthesis of dyes and are particularly suitable diazo components for the synthesis of azo dyes.

专利号:US-7737287-B2
优先权日:2002-03-28
标 题 :Anomeric derivatives of monosaccharides
发明人：MEUTERMANS WIM; WEST MICHAEL LEO; GIANG THANH LE; ADAMSON GEORGE; SCHAFER KARL; ABBENANTE GIOVANNI
权利人:ALCHEMIA LTD
摘要:This invention relates to combinatorial libraries of potentially biologically active mainly monosaccharide compounds and to methods of preparing same. These compounds are variously functionalized, with a view to varying lipid solubility, size, function and other properties, with the particular aim of discovering a drug or drug-like compound, or compounds with useful properties. The invention provides intermediates, processes and synthetic strategies for the solution or solid phase synthesis of monosaccharides, variously functionalized about the sugar ring, including the addition of aromaticity and charge, and the placement of amino acid and peptide side chain units of isosteres thereof.

专利号:US-8062756-B2
优先权日:2005-08-26
标题:Stepwise growth of oligomeric redox-active molecules on a surface without the use of protecting groups
发明人：BOCIAN DAVID F; LINDSEY JONATHAN S; JIAO JIEYING
权利人:BOCIAN DAVID F; LINDSEY JONATHAN S; JIAO JIEYING; REGENTS OFT THE UNIVERSITY OF CALIFORNIA; UNIV NORTH CAROLINA STATE
摘要:This invention provides a procedure for growing oligomers via a stepwise process. The oligomers can include porphyrins, which have been previously shown to be attractive candidates for molecular-based information storage. The stepwise synthesis procedure requires no protecting groups, thus eliminating protection/deprotection reactions that add complexity to the process.

专利号:US-3901899-A
优先权日:1973-04-27
标题 :Synthesis of indoles from anilines and intermediates therein
发明人：GASSMAN PAUL G
权利人:UNIV OHIO STATE RES FOUND
摘要:Preparing indoles and intermediates therefor by reacting an Nhaloaniline with a Beta -carbonylic hydrocarbon sulfide to form an azasulfonium halide, reacting the azasulfonium halide with a strong base to form a thio-ether indole derivative, and then reducing the thio-ether indole, e.g. with Raney nickel, to form the indole compound. When an acetal or ketal of the Beta carbonyl hydrocarbon sulfide is used, the azasulfonium salt is treated with a base, and then with an acid to form the thio-ether indole derivative. When an Alpha -ethyl- Beta -carbonylic hydrocarbon sulfide is used, the resulting azosulfonium salt reacts with strong base to form a thio-ether indolenine derivative, which on reduction with Raney nickel or complex metal hydrides yields 3-substituted indoles. The aniline may be an aminopyridine to form an aza-indole compound in the process. The azasulfonium salts and thio-ether indole or thio-ether indolenine derivatives can be isolated and recovered from their respective reaction mixtures. The thio-ether-indole and thio-ether indolenine derivatives are useful as intermediates to make the indoles without the thio-ether group. The indoles are known compounds having a wide variety of uses, e.g., in making perfumes, dyes, amino acids, pharmaceuticals, agricultural chemicals and the like.