CAS: 523-42-2; 1-Isopentyl-4-((1-Isopentylquinolin-4(1H)-Ylidene)Methyl)Quinolin-1-Ium Iodide

该化合物是属于quinoline染色物类的合成有机化合物,其特征为深蓝色,在各种应用中有用,包括生物污点和细胞结构可视化的生理学中.该化合物在有机溶剂中溶解,水中的溶解度有限,这是该类许多染色的典型特征. Quinoline blue具有独特的吸收频谱,在可见范围中吸收最大程度,使色度测定分析有效.此外,还研究了其在光动治疗中的潜在应用,因为其在光动能时能够产生活性氧物种.安全考虑包括潜在毒性,需要谨慎处理和使用期间的适当安全措施.

结构式图片

相似化合物

53213-94-8 1402299-58-4 4727-50-8

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid,Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氢氧化钾体系中,化学反应生成 花青
    参考文献:Hoogewerff; Van Dorp,Recueil Des Travaux Chimiques Des Pays-Bas,1884,Vol. 3,P. 345
    标题:Hoogewerff; Van Dorp,Recueil Des Travaux Chimiques Des Pays-Bas,1884,Vol. 3,P. 345

    海关参考信息

    专利信息


    专利号:US-7241399-B2
    优先权日:2000-09-08
    标题 :Synthesis of nanoparticles
    发明人:HAUBOLD STEPHAN; HAASE MARKUS; RIWOTZKI KARSTEN; WELLER HORST; MEYSSAMY HEIKE; IBARRA FERNANDO
    权利人:CT ANGEWANDTE NANOTECH CAN
    摘要:Methods for the preparation of inorganic nanoparticles capable of fluorescence, wherein the nanoparticles consist of a host material that comprises at least one dopant. The synthesis of the invention in organic solvents allows to gain a considerably higher yield compared to the prior art synthesis in water. All kinds of objects can advantageously be marked and reliably authenticated by using an automated method on the basis of a characteristic emission. Further, the size distribution of the prepared nanoparticles is nartower which renders a subsequent size-selected separation process superfluous.

    专利号:US-10870649-B2
    优先权日:2017-04-13
    标题:Synthesis of NIR fluorescent probe
    发明人:LATTUADA LUCIANO; BUONSANTI FEDERICA; CRIVELLIN FEDERICO; FERRETTI FULVIO; MAISANO FEDERICO; ORIO LAURA; PIZZUTO LORENA
    权利人:BRACCO IMAGING SPA
    摘要:The application relates to a process for the synthesis of a Near Infra-Red (NIR) fluorescent probe which is a cRGD-Cy5.5 conjugate of formula (I) known as DA364 comprising an aza-bicycloalkane based cyclic peptide labelled with a Cy5.5 dye moiety and used in the guided surgery of tumors and pathologic regions.

    专利号:US-10973847-B2
    优先权日:2017-06-30
    标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof
    发明人:JOHNSON JEREMIAH A; GOLDER MATTHEW R
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.

    专利号:US-9365607-B1
    优先权日:2012-07-31
    标题 :Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides
    发明人:SRIVASTAVA SURESH C; YASKO AMY
    权利人:ASED LLC
    摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.

    专利号:US-7691635-B2
    优先权日:2004-03-26
    标题 :Labeling reagents, methods for the synthesis of such reagents and methods for the detection of biological molecules
    发明人:LAAYOUN ALI; BERNAL-MENDEZ ELOY
    权利人:BIOMERIEUX SA
    摘要:The present invention relates to a temperature-stable labeling reagent of formula (0): n nin which:n R 1 represents H or an alkyl, aryl or substituted aryl group, R 2 represents a detectable marker or at least two detectable markers interlinked by at least one multimeric structure, L is a linker arm comprising a linear chain of at least two covalent bonds and n is an integer equal to 0 or 1, R 3 and R 4 represent, independently of one another: H, NO 2 , Cl, Br, F, I, R 2 -(L) n -Y—X—, OR, SR, NR 2 , R, NHCOR, CONHR, COOR, —CO—NH—(CH 2 ) 3 —(O—CH 2 —CH 2 ) 3 —CH 2 —NH—R 2 , —CO—NH—(CH 2 ) 3 —(O—CH 2 —CH 2 ) 4 —CH 2 —NH—R 2 with R=alkyl or aryl, A is a linker arm comprising at least one covalent double bond enabling the conjugation of the diazo function with the aromatic ring and u is an integer between 0 and 2, preferably 0 or 1, —Y—X— represents —CONH—, —NHCO—, —CH 2 O—, —CH 2 S—, —Z— represents —NH—, —NHCO—, —CONH— or —O—, m is an integer between 1 and 10, preferably between 1 and 3, and p is an integer between 1 and 10, preferably between 1 and 3. n The present invention also describes a method for the synthesis of said labels and also applications for the labeling of biological molecules, in particular of nucleic acids, with a labeling reagent bearing the diazomethyl function. n The invention is particularly suitable for use in the field of diagnostics.

    专利号:US-3905999-A
    优先权日:1972-06-20
    标 题 :Synthesis of 2,3-substituted indoles
    发明人:KRUTAK SR JAMES J
    权利人:EASTMAN KODAK CO
    摘要:A process for the production of 2,3-substituted indoles from Alpha -haloaldehydes or derivatives thereof and certain primary or secondary aromatic amines is disclosed. These indoles are useful in the production of Fischer type bases which are utilized as intermediates for the synthesis of cyanine dyes and photochromic compositions.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


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    摘要:Gulliver LSM, Hurst PR. Novel Approaches to Quantify Estradiol-Induced Loss of ERβ1 Protein in Older Mouse Ovarian Surface Epithelium: New Tools to Assess the Role of ER Protein Subtypes in Predisposing to Ovarian Epithelial Cancer Discover Oncology. 2011 Jul 20;2(4):204. doi: 10.1007/s12672-011-0077-3.
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    参考文献:10.1007/s10295-011-1015-7
    摘要:Wang J, Zhang W, Zhong Z, Wei A, Bao Q, Zhang Y, Sun T, Postnikoff A, Meng H, Zhang H. Transcriptome analysis of probiotic Lactobacillus casei Zhang during fermentation in soymilk. Journal of Industrial Microbiology & Biotechnology. 2011 Jul 22;39(1):191–206. doi: 10.1007/s10295-011-1015-7.
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