专利号:WO-2020107913-A1 优先权日:2018-11-26 标题 :Compound or salt thereof, preparation method and uses thereof 发明人:ZHANG BAOXIAN; HU JIE; YAN DONGHUI; QIN MENGZHI; CAO YING 权利人:INCREASEPHARM TIANJIN INST CO LTD 摘要:The present invention discloses a compound shown in a formula I or a salt thereof, wherein R1 is selected from hydrogen, hydroxyl, C1-6 alkyl, substituted C1-6 alkyl, halogen, amino and thiol wherein the substituted C1-6 alkyl group is substituted by one or more halogens. The compound or the salt thereof can be used as impurity reference standard for monitoring the introduction of impurities in the synthesis process of terbutaline or pharmaceutically acceptable salt thereof, so as to ensure efficacy and safety of a drug product.
专利号:CN-115181082-B 优先权日:2022-09-05 标题:A kind of synthesis method of natural molecule Moracin M
专利号:CN-117285413-A 优先权日:2023-08-09 标 题:A kind of synthesis method of terbutaline key intermediate 3,5-dihydroxyacetophenone
专利号:CN-112209841-B 优先权日:2020-10-22 标 题 :Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate
专利号:US-7427690-B2 优先权日:2004-06-05 标 题 :Multifunction “crown complexesâ€? from amino acids and peptides for skin and hair restoration 发明人:GUPTA SHYAM K 权利人:BIODERM RESEARCH 摘要:This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2 . The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.
专利号:CN-109942462-A 优先权日:2019-03-06 标 题:A kind of synthesis technology of bambuter