CAS: 5162-82-3; 3-Chloro-4-Methylbenzoic Acid

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CAS号99-94-5 对甲基苯甲酸 | CAS号124-38-9 二氧化碳 | CAS号95-73-8 2,4-二氯甲苯 | CAS号104-87-0 对甲基苯甲醛 | CAS号3411-03-8 3-氯-4-甲基苯甲醛 | CAS号21423-81-4 3-氯-4-甲基苯甲腈 | CAS号4395-79-3 2-chloro-1-meth... | CAS号95-72-7 2-氯-1,4-二甲基苯 | CAS号2719-40-6 3-氯-4-甲基氯苄 | CAS号2458-12-0 3-氨基-4-甲基苯甲酸 | CAS号56525-63-4 3-氯-4-甲基苯甲酸甲酯 | CAS号39652-34-1 3,5-二氯-4-甲基苯甲酸 | CAS号39652-32-9 3-氯-4-甲基苯甲醇 | CAS号1967-31-3 2-氯对苯二甲酸 | CAS号25539-20-2 2-苯氧基对苯二甲酸 | CAS号95-49-8 邻氯甲苯 | CAS号586-30-1 3-羟基-4-甲基苯甲酸 | CAS号106269-39-0 9-oxoxanthene-3... | CAS号21460-88-8 2,5-二氯-4-甲基苯甲酸 | CAS号99500-36-4 Ethyl 3-chloro-...

对甲基苯甲酸置于十六烷基三甲基溴化铵,氯体系中,用 水 作为反应溶剂,化学反应 8.0H,反应生成 3-氯-4-甲基苯甲酸
参考文献:一种卤代苯甲酸衍生物的工业化合成方法
标题:一种卤代苯甲酸衍生物的工业化合成方法
摘要:本发明公开了一种卤代苯甲酸衍生物的工业化合成方法,所述卤代苯甲酸衍生物具有以下通式(I):其中,若干个r为c1~c20的烷基,若干个x为卤素;并且,所述工业化合成方法包括以下步骤:将烷基取代的苯甲酸和水加入至反应容器中,并加入卤素单质,加热反应,反应完全,后处理,即得目标产物卤代苯甲酸衍生物.该卤代苯甲酸衍生物的工业化合成方法无需溶剂回收,能耗少,三废少,副产物氢卤酸可以直接出售或者用于其它产品的生产;因此,所述卤代苯甲酸衍生物的工业化合成方法安全环保,成本低廉,从而具有广阔的工业化应用前景.

专利信息

专利号:EP-3515880-B1
优先权日:2017-03-17
标题:Methods and compositions for synthesis of encoded libraries
发明人：LI JIN; MORGAN BARRY A; Wan jinqiao; DOU DENGFENG; LIU GUANSAI; CHANG YONG; CHEN QIUXIA; WANG XING; XU YANSHAN; HU DONGYAN; LIU JIAN; CHENG XUEMIN
权利人:HITGEN INC

专利号:US-2020149034-A1
优先权日:2017-03-17
标题:Methods and Compositions for Synthesis of Encoded Libraries

专利号:US-12227528-B2
优先权日:2017-11-09
标 题:Glucose-sensitive albumin-binding derivatives
发明人：KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA
权利人:NOVO NORDISK AS
摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.

专利号:WO-2013015203-A1
优先权日:2011-07-28
标 题:Isopropyl 3-chloro-4-methylbenzoate and method for producing same
发明人：KATO TOMOKI; KAI Ryota; KOBAYASHI YUKIMOTO
权利人:NIPPON LIGHT METAL CO; TORAY FINECHEMICALS CO LTD; KATO TOMOKI; KAI Ryota; KOBAYASHI YUKIMOTO
摘要:Provided is isopropyl 3-chloro-4-methylbenzoate, which is a novel substance that is useful as an intermediate for the synthesis of functional polymer materials, agrichemicals, pharmaceuticals, and the like. Also provided is a method for producing the same. Isopropyl 3-chloro-4-methylbenzoate represented by formula (1) is produced by the method whereby 4-chloro-methylbenzoic acid chloride is subjected to nuclear chlorination in the presence of chlorine and a Lewis acid catalyst, the resulting 3-chloro-4-methylbenzoic acid chloride is esterified by isopropyl alcohol, and isopropyl 3-chloro-4-methylbenzoate is produced.

专利号:EP-2341140-B1
优先权日:2005-12-01
标 题 :Enzymatic encoding methods for efficient synthesis of large libraries