专利号:US-7268144-B2 优先权日:2004-04-14 标 题 :Regiospecific synthesis of rapamycin 42-ester derivatives 发明人:GU JIANXIN; CAI PING; RUPPEN MARK E 权利人:WYETH CORP 摘要:A method for the regiospecific synthesis of rapamycin 42-ester derivatives is described. The method involves lipase-catalyzed acetylation of 42-hydroxy of rapamycin with an acyl donor such as a vinyl ester, an isopropenyl ester or an anhydride in a suitable organic solvent.
专利号:US-6281372-B1 优先权日:1999-02-26 标 题 :Process for synthesis of vinyl esters from butene oligomers 发明人:WIESE KLAUS-DIETHER; OLBRICH PAUL; GABRIEL JUERGEN 权利人:OXENO OLEFINCHEMIE GMBH 摘要:A process for the synthesis of vinyl esters from butene oligomers, wherein butenes are oligomerized, the butene oligomers are separated from the oligomerized mixture, the butene oligomers are converted to carboxylic acids which are longer by one carbon atom, and the resulting carboxylic acids are converted to the corresponding vinyl esters. The butene oligomers are in particular dibutene, tributene and tetrabutene. The invention also relates to the use of the vinyl esters as plasticizers or as comonomers in polymerization reactions.
专利号:US-2004147789-A1 优先权日:2000-02-11 标题 :Allyl esters substituted by a difluoromethylene group, their process of synthesis and their use, and a process for functionalizing a double bond 发明人:ROQUES NICOLAS 权利人:RHODIA CHIMIE SA 摘要:This invention provides compounds of formula: n n n in which R f is a radical that carries a perfluoromethylene group, which group ensures bonding to the remainder of the molecule; R1 and R3, which can be the same or different, are chosen from among hydrogen and alkyl or aryl radicals; Ψ is an electroattractor group such that Ψ-O—H is an acid whose pKa (in water) is at most equal to 8, advantageously 6, and preferably 5. These compounds are useful for the synthesis of nitrogen-containing heterocyclic compounds.
专利号:US-7351781-B2 优先权日:2001-04-24 标题 :Synthesis of vinyl polymers by controlled radical polymerization 发明人:WHITE DANIELA; O'DWYER JAMES B 权利人:PPG IND OHIO INC 摘要:A controlled free radical polymerization process, which includes the steps of: adding a monofunctional iniferter compound to an oxygen-free solvent; heating the solution to a temperature sufficient to allow the iniferter compound to form two carbon centered radical residues; adding a first monomer composition comprising one or more monomers to the solution containing the radical containing residues; polymerizing the first monomer composition to form a quasi-living polymer; and optionally polymerizing a second monomer composition comprising one or more monomers, which are different than the first monomer composition. The resulting non-random copolymer having the general formula:n nφ-[-A p -B s -] t -φn nwhere A and B are different compositions of ethylenically unsaturated monomers; p is an integer from 1 to 1,000; s is an integer from 0 to 1,000; t is an integer from 1 to 100; and φ is a residue from the iniferter.
专利号:US-2024174785-A1 优先权日:2021-03-10 标题 :Method for producing polymer, composition for radical polymerization, and radical polymerization inhibitor 发明人:TAKAYAMA TAKUMI; TSUCHIYA HINAKO; MAEKAWA KAZUHIKO 权利人:KURARAY CO 摘要:A method of producing a polymer including a polymerization step of obtaining a polymer by controlled radical polymerization of a monomer (Y) in the presence of an organic compound (A) represented by formula (I) and its constituents and a radical generator (B), where a molar ratio (B/A) of (B) to (A) is from 0.5 to 20. The production method allows synthesis of a highly safe polymer with a high molecular weight while precisely controlling the molecular sequence and the end structure. In addition, the production method is low in toxicity, environmentally friendly, and operated at low costs.
专利号:US-2003018151-A1 优先权日:2001-04-24 标题 :Synthesis of vinyl polymers by controlled radical polymerization
参考标题:Preparation Of Optically Active Cycloalkenes Bearing All-Carbon Quaternary Stereogenic Centres Via Lipase-Oxovanadium Combo-Catalysed Dynamic Kinetic Resolution 作者:Shinji Kawanishi,Koji Sugiyama,Yasuhiro Oki,Takashi Ikawa,Shuji Akai 摘要:In This Study, A Novel Asymmetric Synthesis Of All-Carbon Quaternary Stereogenic Centres Is Developed By The Connection Of Three Prochiral Or Achiral Components--Conjugated Enones, Organometallic Compounds And Vinyl Esters--At The...
合成参考文献
摘要:Yamashita, Y.; Gröger, H., Science of Synthesis, (2019) , 343. 摘要:Kanomata, K.; Akai, S., Science of Synthesis, (2022) , 202. 摘要:Kanomata, K.; Akai, S., Science of Synthesis, (2022) , 206. 参考文献:10.1016/j.jbiosc.2011.04.004 摘要:Kaewprapan K, Wongkongkatep J, Panbangred W, Phinyocheep P, Marie E, Durand A, Inprakhon P. Lipase-catalyzed synthesis of hydrophobically modified dextrans: Activity and regioselectivity of lipase from Candida rugosa. Journal of Bioscience and Bioengineering. 2011 Aug;112(2):124–9. doi: 10.1016/j.jbiosc.2011.04.004.