专利号:US-7534906-B2 优先权日:2002-06-28 标 题:Process for the synthesis of hydrogenofluoromethylenesulphonyl radical derivatives 发明人:SAINT-JALMES LAURENT 权利人:RHODIA CHIMIE SA 摘要:The invention concerns a method for synthesis of hydrogenofluoromethylenesulphonyl radical derivatives, comprising: a) a step which consists in condensing a thiolate (that is a monoalkyl sulphide salt) with a compound having a sp; 3hybridized carbon bearing a hydrogen, a fluorine, a heavy halogen selected among chlorine, bromine and iodine and an electron-attracting group selected among fluorine and those whereof the; is not less than 0.2, advantageously than 0.4; b) a step which consists in oxidizing the compound obtained in step a). The invention is applicable to the synthesis of various compounds having a suphinyl or sulphonyl group.
专利号:US-9126995-B2 优先权日:2011-11-08 标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound 发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU 权利人:NISSAN CHEMICAL IND LTD 摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.
专利号:US-8759584-B2 优先权日:2007-12-14 标 题 :Synthesis of biguanidines and triazines, and biguanidino-aluminium complexes as intermediates 发明人:FORD MARK JAMES 权利人:FORD MARK JAMES; BAYER CROPSCIENCE AG 摘要:Compounds of formula (I) or salts thereof, n nin which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , X and Y are defined as in claim 1 , can be prepared by a process characterized in that a compound of the formula (II) or a salt thereof,n n nis reacted to a compound of the formula (III) or a salt thereof,n n nand an aluminium(III) source, optionally, in the presence of a protic additive or solvent selected from the group consisting of alcohols or amines.n n The compounds (I) are suitable to be used for the preparation of heterocyclic compounds corresponding to (I) where the group Al(X)(Y) is replaced with an optionally substituted carbon atom, or s-triazine derivatives thereof.
专利号:US-5057634-A 优先权日:1989-12-19 标 题 :Multistep synthesis of hexafluoropropylene 发明人:WEBSTER JAMES L; MCCANN ELREY L; BRUHNKE DOUGLAS W; LEROU JAN J; MANOGUE WILLIAM H; MANZER LEO E; SWEARINGEN STEVEN H; TROFIMENKO SWIATOSLAW; BONIFAZ CRISTOBAL 权利人:DU PONT 摘要:The present invention relates to multistep syntheses of hexafluoropropylene from acyclic three-carbon hydrocarbons or partially halogenated acyclic three-carbon hydrocarbons. In all these syntheses the first step is a vapor-phase chlorofluorination of the starting material to one or more saturated chlorofluorocarbons. Novel catalysts are also provided.
专利号:US-5220083-A 优先权日:1989-12-19 标题:Synthesis of perfluoropropane 发明人:WEBSTER JAMES L; SWEARINGEN STEVEN H; BRUHNKE DOUGLAS W; MANZER LEO E; MCCANN ELREY L 权利人:DU PONT 摘要:The present invention relates to syntheses of perfluoropropane- .e., octafluoropropane-from acyclic three-carbon hydrocarbons or partially or totally halogenated acyclic three-carbon hydrocarbons.
专利号:US-5986132-A 优先权日:1995-11-18 标 题 :Synthesis of carboxylic acid derivatives 发明人:REEVE MAXWELL; BOWLES STEPHEN ARTHUR 权利人:BRITISH BIOTECH PHARM 摘要:Compounds of formula (I) wherein R 1 , R 2 , R 3 , R 4 , X are as defined in the specification and are prepared by elimination of one of the groups X 1 and X 2 from a compound of formula (II) wherein X 1 and X 2 each independently represent a carboxylic acid group or salt thereof, or a protected carboxylic acid group, the non-eliminated group X 1 or X 2 corresponding to the group X in the desired compound of formula (I). ##STR1##
摘要:Carroll, M. A., Science of Synthesis, (2005) 34, 51. 摘要:Dax, K., Science of Synthesis, (2005) 34, 129. 摘要:Carroll, M. A., Science of Synthesis, (2005) 34, 50. 摘要:Black, D. A.; Fagnou, K., Science of Synthesis, (2010) 45, 627.